(Q28487411)

English

Crystal structure and activity studies of the Mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics

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scholarly article

1 reference

24 January 2017

Crystal structure and activity studies of the Mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics (English)

1 reference

24 January 2017

antibiotic resistance

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crystal structure

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Mycobacterium tuberculosis

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object named as

Feng Wang

1

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author name string

Craig Cassidy

2

1 reference

24 January 2017

James C. Sacchettini

3

1 reference

24 January 2017

language of work or name

0 references

publication date

1 August 2006

1 reference

24 January 2017

Antimicrobial Agents and Chemotherapy

1 reference

24 January 2017

50

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24 January 2017

2762–2771

1 reference

24 January 2017

8

1 reference

24 January 2017

The CCP4 suite: programs for protein crystallography

1 reference

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19 March 2017

Improved prediction of signal peptides: SignalP 3.0

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19 March 2017

Tazobactam forms a stoichiometric trans-enamine intermediate in the E166A variant of SHV-1 beta-lactamase: 1.63 A crystal structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

19 March 2017

Crystal structure of extended-spectrum beta-lactamase Toho-1: insights into the molecular mechanism for catalytic reaction and substrate specificity expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

19 March 2017

Ultrahigh resolution structure of a class A beta-lactamase: on the mechanism and specificity of the extended-spectrum SHV-2 enzyme

1 reference

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19 March 2017

Acyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillin

1 reference

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19 March 2017

An ultrahigh resolution structure of TEM-1 beta-lactamase suggests a role for Glu166 as the general base in acylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

19 March 2017

Structure of an extended-spectrum class A beta-lactamase from Proteus vulgaris K1

1 reference

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19 March 2017

Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin

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19 March 2017

Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam

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19 March 2017

Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies

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19 March 2017

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

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19 March 2017

Susceptibility of multidrug-resistant strains of Mycobacterium tuberculosis to amoxycillin in combination with clavulanic acid and ethambutol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

19 March 2017

Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

19 March 2017

X-ray analysis of the NMC-A beta-lactamase at 1.64-A resolution, a class A carbapenemase with broad substrate specificity

1 reference

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19 March 2017

Contribution of beta-lactamases to beta-lactam susceptibilities of susceptible and multidrug-resistant Mycobacterium tuberculosis clinical isolates

1 reference

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19 March 2017

Recombinant expression and characterization of the major beta-lactamase of Mycobacterium tuberculosis.

1 reference

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19 March 2017

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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19 March 2017

Can penicillins and other beta-lactam antibiotics be used to treat tuberculosis?

1 reference

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19 March 2017

Dali: a network tool for protein structure comparison

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19 March 2017

A functional classification scheme for beta-lactamases and its correlation with molecular structure

1 reference

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19 March 2017

beta-Lactamase inhibitors and the inducibility of the beta-lactamase of Mycobacterium tuberculosis

1 reference

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19 March 2017

Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

1 reference

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19 March 2017

The development of penicillin: genesis of a famous antibiotic.

1 reference

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29 September 2017

Characterization of novel Mycobacterium tuberculosis and Mycobacterium smegmatis mutants hypersusceptible to beta-lactam antibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

29 September 2017

Bacterial resistance to beta-lactam antibiotics: compelling opportunism, compelling opportunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

29 September 2017

Molecular basis of antibiotic resistance and beta-lactamase inhibition by mechanism-based inactivators: perspectives and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

29 September 2017

Class A beta-lactamases--enzyme-inhibitor interactions and resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

29 September 2017

The bla gene of the cephamycin cluster of Streptomyces clavuligerus encodes a class A beta-lactamase of low enzymatic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

29 September 2017

Critical hydrogen bonding by serine 235 for cephalosporinase activity of TEM-1 beta-lactamase

1 reference

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29 September 2017

Inactivation of antibiotics and the dissemination of resistance genes

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29 September 2017

Lipoproteins of gram-positive bacteria

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29 September 2017

Beta-lactamases and bacterial resistance to antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

29 September 2017

Glyceride-cysteine lipoproteins and secretion by Gram-positive bacteria

1 reference

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29 September 2017

Role of the conserved amino acids of the 'SDN' loop (Ser130, Asp131 and Asn132) in a class A beta-lactamase studied by site-directed mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1538687

29 September 2017

Interplay of cell wall barrier and beta-lactamase activity determines high resistance to beta-lactam antibiotics in Mycobacterium chelonae

1 reference

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29 September 2017

Directed selective pressure on a beta-lactamase to analyse molecular changes involved in development of enzyme function

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29 September 2017

Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics

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2 June 2018

The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution

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2 June 2018

In-vitro susceptibility of Mycobacterium tuberculosis, Mycobacterium bovis and Mycobacterium kansasii to amoxycillin and ticarcillin in combination with clavulanic acid

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2 June 2018

Bacterial resistance to beta-lactam antibiotics: crystal structure of beta-lactamase from Staphylococcus aureus PC1 at 2.5 A resolution.

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2 June 2018

Comparison of four beta-lactamase inhibitors in combination with ampicillin against Mycobacterium tuberculosis

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2 June 2018

A standard numbering scheme for the class A beta-lactamases

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2 June 2018

Porins in the Cell Wall of Mycobacteria

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2 June 2018

The effect of penicillin on the tubercle bacillus.

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27 November 2018

Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

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27 November 2018

Genetic analysis of the beta-lactamases of Mycobacterium tuberculosis and Mycobacterium smegmatis and susceptibility to beta-lactam antibiotics

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27 November 2018

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27 November 2018

The vitro efficacy of beta-lactam and beta-lactamase inhibitors against multidrug resistant clinical strains of Mycobacterium tuberculosis

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27 November 2018

Effects on substrate profile by mutational substitutions at positions 164 and 179 of the class A TEM(pUC19) beta-lactamase from Escherichia coli.

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27 November 2018

Carbapenems: the pinnacle of the beta-lactam antibiotics or room for improvement?

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12 December 2020

based on heuristic

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Processing of X-ray diffraction data collected in oscillation mode

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https://pubmed.ncbi.nlm.nih.gov/16870770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of β-lactamase production to the resistance of mycobacteria to β-lactam antibiotics

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https://pubmed.ncbi.nlm.nih.gov/16870770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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