(Q28488158)

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Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia a: a computational assessment

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scholarly article

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Polymorphisms in the F8 gene and MHC-II variants as risk factors for the development of inhibitory anti-factor VIII antibodies during the treatment of hemophilia a: a computational assessment (English)

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Coagulation factor VIII

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1 reference

based on heuristic

inferred from title

object named as

Chen Yanover

2

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author name string

Gouri Shankar Pandey

1

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Tom E Howard

3

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Zuben E Sauna

4

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language of work or name

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publication date

2013

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PLOS Computational Biology

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9

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5

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e1003066

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copyright license

Creative Commons CC0 License

16 May 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

19 March 2017

CD4+ T-cell epitopes associated with antibody responses after intravenously and subcutaneously applied human FVIII in humanized hemophilic E17 HLA-DRB1*1501 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

NetMHCIIpan-2.0 - Improved pan-specific HLA-DR predictions using a novel concurrent alignment and weight optimization training procedure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Improvements in factor concentrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

MHC class II epitope predictive algorithms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Peptide-MHC class II complex stability governs CD4 T cell clonal selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Inhibitors of factor VIII in black patients with hemophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Factor VIII inhibitors: risk factors and methods for prevention and immune modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Inhibitor development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Dynamics of factor VIII interactions determine its immunologic fate in hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

CD4+ T-cell clones specific for wild-type factor VIII: a molecular mechanism responsible for a higher incidence of inhibitor formation in mild/moderate hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

The hemophilias--from royal genes to gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

29 September 2017

Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

2 June 2018

Irreversible association of peptides with class II MHC molecules in living cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

2 June 2018

Loss of high-responder inhibitors in patients with severe hemophilia A and human immunodeficiency virus type 1 infection: a report from the Multi-Center Hemophilia Cohort Study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003066

21 January 2018

ProPred: prediction of HLA-DR binding sites.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003066

21 January 2018

Predicting class II MHC/peptide multi-level binding with an iterative stepwise discriminant analysis meta-algorithm

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003066

21 January 2018

Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003066

21 January 2018

The impact of HLA-B micropolymorphism outside primary peptide anchor pockets on the CTL response to CMV

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1003066

21 January 2018

Prevention and treatment of factor VIII inhibitors in murine hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

27 November 2018

Antifactor VIII antibody inhibiting allogeneic but not autologous factor VIII in patients with mild hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

27 November 2018

The missense mutation Arg593 --> Cys is related to antibody formation in a patient with mild hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656107

27 November 2018

Inhibitors to factor VIII in a family with mild hemophilia: molecular characterization and response to factor VIII and desmopressin

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696725

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some factor VIII (FVIII) inhibitors recognise a FVIII epitope(s) that is present only on FVIII-vWF complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696725

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23696725

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PCBI.1003066

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DBLP publication ID

journals/ploscb/PandeyYHS13

1 reference

DBLP Dataset 2021-01-02

28 January 2021

PMC publication ID

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PubMed publication ID

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ResearchGate publication ID

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