(Q28507501)

24 January 2017

title

A functional mouse retroposed gene Rps23r1 reduces Alzheimer's beta-amyloid levels and tau phosphorylation (English)

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24 January 2017

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Paul Greengard

14

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Xiumei Huang

6

object named as

Xiumei Huang

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24 January 2017

Yun-wu Zhang

1

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24 January 2017

Shijie Liu

2

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24 January 2017

Xue Zhang

3

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24 January 2017

Wu-Bo Li

4

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24 January 2017

Yaomin Chen

5

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24 January 2017

Liangwu Sun

7

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24 January 2017

Wenjie Luo

8

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24 January 2017

William J. Netzer

9

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24 January 2017

Richard Threadgill

10

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24 January 2017

Gordon Wiegand

11

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24 January 2017

Ruishan Wang

12

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24 January 2017

Stanley N. Cohen

13

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24 January 2017

Francesca-Fang Liao

15

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24 January 2017

Limin Li

16

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24 January 2017

Huaxi Xu

17

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24 January 2017

language of work or name

English

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publication date

12 November 2009

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24 January 2017

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24 January 2017

volume

64

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24 January 2017

issue

3

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24 January 2017

page(s)

328–340

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RNA-based gene duplication: mechanistic and evolutionary insights

24 January 2017

cites work

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19 March 2017

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Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

19 March 2017

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19 March 2017

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GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

19 March 2017

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Identification and analysis of over 2000 ribosomal protein pseudogenes in the human genome

19 March 2017

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

19 March 2017

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Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

19 March 2017

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A cDNA sequence of human ribosomal protein, homologue of yeast S28

19 March 2017

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Human metallothionein genes--primary structure of the metallothionein-II gene and a related processed gene

19 March 2017

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Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns

19 March 2017

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19 March 2017

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

7 April 2017

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

7 April 2017

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Neurodegenerative tauopathies

7 April 2017

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7 April 2017

Vertebrate pseudogenes

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Glycogen synthase kinase-3 (GSK-3) inhibitors reach the clinic.

7 April 2017

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Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism

29 September 2017

1 reference

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The Alzheimer's disease beta-secretase enzyme, BACE1.

29 September 2017

1 reference

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Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design.

29 September 2017

1 reference

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Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice

29 September 2017

1 reference

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Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease

29 September 2017

1 reference

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Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation

29 September 2017

1 reference

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Current topics in genome evolution: molecular mechanisms of new gene formation

29 September 2017

1 reference

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Txr1: a transcriptional regulator of thrombospondin-1 that modulates cellular sensitivity to taxanes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Evolutionary fate of retroposed gene copies in the human genome

29 September 2017

1 reference

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Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Comparative analysis of processed pseudogenes in the mouse and human genomes

29 September 2017

1 reference

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Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

29 September 2017

1 reference

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Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation

29 September 2017

1 reference

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GSK3 takes centre stage more than 20 years after its discovery

29 September 2017

1 reference

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Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.

29 September 2017

1 reference

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BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

29 September 2017

1 reference

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A common enzyme connects notch signaling and Alzheimer's disease

29 September 2017

1 reference

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Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

29 September 2017

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Antisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis

29 September 2017

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Reversible tumorigenesis induced by deficiency of vasodilator-stimulated phosphoprotein

29 September 2017

1 reference

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Unusual phenotypic alteration of beta amyloid precursor protein (betaAPP) maturation by a new Val-715 --> Met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiop

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

In contrast to kindled seizures, the frequency of spontaneous epilepsy in the limbic status model correlates with greater aberrant fascia dentata excitatory and inhibitory axon sprouting, and increased staining for N-methyl-D-aspartate, AMPA and GAB

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Neoplastic transformation and tumorigenesis associated with sam68 protein deficiency in cultured murine fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Tsg101: a novel tumor susceptibility gene isolated by controlled homozygous functional knockout of allelic loci in mammalian cells

2 June 2018

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Processed pseudogenes inDrosophila

2 June 2018

1 reference

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Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Processed genes: a dispersed human immunoglobulin gene bearing evidence of RNA-type processing

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3846276

Protein kinase A as a biological target in cancer therapy

27 November 2018

1 reference

12 December 2020

Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3 beta in rat hippocampal neurons

1 reference

12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

12 December 2020

Phosphorylation of human tau protein by microtubule-associated kinases: GSK3beta and cdk5 are key participants

1 reference

12 December 2020

10.1016/J.NEURON.2009.08.036

Identifiers

DOI

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