(Q28508394)

24 January 2017

title

TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control (English)

1 reference

Voltage-dependent anion channel 1

24 January 2017

0 references

1 reference

GOA release 2020-03-11

1 reference

Protein kinase C, epsilon

GOA release 2020-03-11

1 reference

Peter Joseph Jacques Parker

GOA release 2020-03-11

1 reference

Robert Harvey

5

0 references

object named as

Peter Parker

7

0 references

author name string

Jemma Gatliff

1

1 reference

24 January 2017

Daniel East

2

1 reference

24 January 2017

James Crosby

3

1 reference

24 January 2017

Rosella Abeti

4

1 reference

24 January 2017

William Craigen

6

1 reference

24 January 2017

Michelangelo Campanella

8

1 reference

24 January 2017

language of work or name

1 reference

1 January 2014

1 reference

24 January 2017

1 reference

24 January 2017

volume

10

1 reference

24 January 2017

issue

12

1 reference

24 January 2017

page(s)

2279–2296

1 reference

describes a project that uses

24 January 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4502750/fullTextXML

inferred from PubMed Central ID database lookup

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Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

19 March 2017

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Regulation of the inner membrane mitochondrial permeability transition by the outer membrane translocator protein (peripheral benzodiazepine receptor)

19 March 2017

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p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

19 March 2017

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19 March 2017

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19 March 2017

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

19 March 2017

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19 March 2017

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

19 March 2017

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The potential anticancer agent PK11195 induces apoptosis irrespective of p53 and ATM status in chronic lymphocytic leukemia cells

19 March 2017

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

19 March 2017

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19 March 2017

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S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

19 March 2017

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19 March 2017

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Recombinant expression of the voltage-dependent anion channel enhances the transfer of Ca2+ microdomains to mitochondria

19 March 2017

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19 March 2017

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

19 March 2017

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

19 March 2017

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Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

19 March 2017

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Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors

19 March 2017

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Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

19 March 2017

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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

19 March 2017

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7 April 2017

Mitochondria and cancer

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Mitochondrial fission, fusion, and stress

7 April 2017

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During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

7 April 2017

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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

7 April 2017

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

7 April 2017

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

7 April 2017

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Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Molecular Regulation of the Mitochondrial F(1)F(o)-ATPsynthase: Physiological and Pathological Significance of the Inhibitory Factor 1 (IF(1)).

29 September 2017

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The 18 kDa translocator protein (TSPO): a new perspective in mitochondrial biology

29 September 2017

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Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control

29 September 2017

1 reference

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p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Neuroinflammation in the living brain of Parkinson's disease

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Phorbol-12-myristate 13-acetate acting through protein kinase Cepsilon induces translocator protein (18-kDa) TSPO gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Mitochondrial ND5 gene variation associated with encephalomyopathy and mitochondrial ATP consumption

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

PK11195, a peripheral benzodiazepine receptor (pBR) ligand, broadly blocks drug efflux to chemosensitize leukemia and myeloma cells by a pBR-independent, direct transporter-modulating mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Rapid Ca2+-dependent decrease of protein ubiquitination at synapses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Relation of cell proliferation to expression of peripheral benzodiazepine receptors in human breast cancer cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Each mammalian mitochondrial outer membrane porin protein is dispensable: effects on cellular respiration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Peripheral-type benzodiazepine/diazepam binding inhibitor receptor: biological role in steroidogenic cell function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

The peripheral-type benzodiazepine receptor: a protein of mitochondrial outer membranes utilizing porphyrins as endogenous ligands

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Methyl-beta-cyclodextrin induces mitochondrial cholesterol depletion and alters the mitochondrial structure and bioenergetics

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

IF1, the endogenous regulator of the F(1)F(o)-ATPsynthase, defines mitochondrial volume fraction in HeLa cells by regulating autophagy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Altered detoxification status and increased resistance to oxidative stress by K-ras transformation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

The peripheral-type benzodiazepine receptor. Localization to the mitochondrial outer membrane.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Peripheral-type benzodiazepine receptors in endocrine organs: autoradiographic localization in rat pituitary, adrenal, and testis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Effects of peripheral benzodiazepines upon the O2 consumption of neuroblastoma cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Antiproliferative effect of peripheral benzodiazepine receptor antagonist PK11195 in rat mammary tumor cells

2 June 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

Up-regulation of the peripheral benzodiazepine receptor during human colorectal carcinogenesis and tumor spread

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

In vivo imaging of neuroinflammation: a comparative study between [(18)F]PBR111, [ (11)C]CLINME and [ (11)C]PK11195 in an acute rodent model

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

Microglial activation and dopamine terminal loss in early Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

VDAC: the channel at the interface between mitochondria and the cytosol.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

Calcium binding and translocation by the voltage-dependent anion channel: a possible regulatory mechanism in mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

Regulation of metabolite flux through voltage-gating of VDAC channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

S-nitrosylation regulates mitochondrial quality control via activation of parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

The mitochondrial permeability transition pore may comprise VDAC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2F15548627.2014.991665

PK11195 inhibits mitophagy targeting the F1Fo-ATPsynthase in Bcl-2 knock-down cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Mitochondrial benzodiazepine receptors mediate inhibition of mitochondrial respiratory control

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4502750

Topography of the Leydig cell mitochondrial peripheral-type benzodiazepine receptor

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25470454

12 December 2020

inferred from PubMed ID database lookup

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

1 reference

https://pubmed.ncbi.nlm.nih.gov/25470454

12 December 2020

inferred from PubMed ID database lookup

Expression of peripheral-type benzodiazepine receptor and diazepam binding inhibitor in human astrocytomas: relationship to cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25470454

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4161/15548627.2014.991665

1 reference

1 reference

1 reference

1 reference