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Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice
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scholarly article
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
title
Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice
(English)
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
main subject
Paxillin
1 reference
stated in
GOA release 2020-03-11
Parvin, alpha
1 reference
stated in
GOA release 2020-03-11
Integrin linked kinase
1 reference
stated in
GOA release 2020-03-11
author
Reinhard Fässler
series ordinal
7
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author name string
Daniel Moik
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
Anika Böttcher
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
Tatiana Makhina
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
Carsten Grashoff
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
Nada Bulus
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
Roy Zent
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
language of work or name
English
0 references
publication date
28 June 2013
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
published in
Journal of Biological Chemistry
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
volume
288
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
page(s)
18863–18871
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stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
issue
26
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3696662/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response
1 reference
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PubMed Central
reference URL
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19 March 2017
NIH Image to ImageJ: 25 years of image analysis
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19 March 2017
Structural basis for paxillin binding and focal adhesion targeting of β-parvin
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19 March 2017
The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions
1 reference
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PubMed Central
reference URL
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19 March 2017
Integrin-linked kinase is an adaptor with essential functions during mouse development
1 reference
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PubMed Central
reference URL
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19 March 2017
Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling
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Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates
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19 March 2017
The structural basis of integrin-linked kinase-PINCH interactions
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19 March 2017
Structural Analysis of the Interactions Between Paxillin LD Motifs and α-Parvin
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19 March 2017
Paxillin comes of age
1 reference
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PubMed Central
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19 March 2017
The Structure of -Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly
1 reference
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PubMed Central
reference URL
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19 March 2017
NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model
1 reference
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PubMed Central
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19 March 2017
PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival
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19 March 2017
Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662
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19 March 2017
Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662
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19 March 2017
The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling
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PubMed Central
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19 March 2017
Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions
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PubMed Central
reference URL
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19 March 2017
Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways
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PubMed Central
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19 March 2017
Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice
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19 March 2017
Consequences of lack of beta 1 integrin gene expression in mice
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19 March 2017
FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin
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29 September 2017
Genetic analyses of integrin signaling
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PubMed Central
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29 September 2017
Endothelial precursor cell migration during vasculogenesis
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PubMed Central
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29 September 2017
Integrin-linked kinase is required for epidermal and hair follicle morphogenesis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662
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29 September 2017
Integrin-linked kinase regulates endothelial cell survival and vascular development.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662
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29 September 2017
Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis
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PubMed Central
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29 September 2017
Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase
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PubMed Central
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29 September 2017
Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization
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29 September 2017
TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis
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29 September 2017
Analysis of homozygous TGF beta 1 null mouse embryos demonstrates defects in yolk sac vasculogenesis and hematopoiesis
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PubMed Central
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29 September 2017
Large T antigens of simian virus 40 and polyomavirus efficiently establish primary fibroblasts
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662
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29 September 2017
Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662
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2 June 2018
Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662
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2 June 2018
Integrin-linked kinase at a glance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M113.470476
retrieved
21 January 2018
Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M113.470476
retrieved
21 January 2018
Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M113.470476
retrieved
21 January 2018
Harnessing homologous recombination in vitro to generate recombinant DNA via SLIC.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1074%2FJBC.M113.470476
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21 January 2018
Loss of migfilin expression has no overt consequences on murine development and homeostasis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M113.470476
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21 January 2018
Stabilization of integrin-linked kinase by binding to Hsp90.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M113.470476
retrieved
21 January 2018
Bypass of lethality with mosaic mice generated by Cre– loxP -mediated recombination
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1074%2FJBC.M113.470476
retrieved
21 January 2018
Identifiers
DOI
10.1074/JBC.M113.470476
0 references
PMCID
3696662
0 references
PubMed ID
23658024
1 reference
stated in
PubMed
PubMed ID
23658024
retrieved
24 January 2017
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