(Q28508913)

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Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice

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PubMed publication ID

24 January 2017

Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice (English)

1 reference

PubMed publication ID

24 January 2017

1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

Integrin linked kinase

1 reference

GOA release 2020-03-11

Reinhard Fässler

7

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author name string

Daniel Moik

1

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PubMed publication ID

24 January 2017

Anika Böttcher

2

1 reference

PubMed publication ID

24 January 2017

Tatiana Makhina

3

1 reference

PubMed publication ID

24 January 2017

Carsten Grashoff

4

1 reference

PubMed publication ID

24 January 2017

Nada Bulus

5

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PubMed publication ID

24 January 2017

Roy Zent

6

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PubMed publication ID

24 January 2017

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publication date

28 June 2013

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PubMed publication ID

24 January 2017

Journal of Biological Chemistry

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PubMed publication ID

24 January 2017

288

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PubMed publication ID

24 January 2017

26

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PubMed publication ID

24 January 2017

18863–18871

1 reference

PubMed publication ID

24 January 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3696662/fullTextXML

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inferred from PubMed Central ID database lookup

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

1 reference

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19 March 2017

NIH Image to ImageJ: 25 years of image analysis

1 reference

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19 March 2017

Structural basis for paxillin binding and focal adhesion targeting of β-parvin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Integrin-linked kinase is an adaptor with essential functions during mouse development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Alpha-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

1 reference

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Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

1 reference

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19 March 2017

The structural basis of integrin-linked kinase-PINCH interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Structural Analysis of the Interactions Between Paxillin LD Motifs and α-Parvin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Paxillin comes of age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

The Structure of -Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

NMR solution structure of the focal adhesion targeting domain of focal adhesion kinase in complex with a paxillin LD peptide: evidence for a two-site binding model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

Consequences of lack of beta 1 integrin gene expression in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

19 March 2017

FGF receptors 1 and 2 are key regulators of keratinocyte migration in vitro and in wounded skin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

Genetic analyses of integrin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

Endothelial precursor cell migration during vasculogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

Integrin-linked kinase is required for epidermal and hair follicle morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

Integrin-linked kinase regulates endothelial cell survival and vascular development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3696662

29 September 2017

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

1 reference

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29 September 2017

Analysis of homozygous TGF beta 1 null mouse embryos demonstrates defects in yolk sac vasculogenesis and hematopoiesis

1 reference

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Large T antigens of simian virus 40 and polyomavirus efficiently establish primary fibroblasts

1 reference

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29 September 2017

Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae

1 reference

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2 June 2018

Molecular dissection of the ILK-PINCH-parvin triad reveals a fundamental role for the ILK kinase domain in the late stages of focal-adhesion maturation

1 reference

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2 June 2018

Integrin-linked kinase at a glance.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.470476

21 January 2018

Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.470476

21 January 2018

Induction of membrane circular dorsal ruffles requires co-signalling of integrin-ILK-complex and EGF receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.470476

21 January 2018

Harnessing homologous recombination in vitro to generate recombinant DNA via SLIC.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.470476

21 January 2018

Loss of migfilin expression has no overt consequences on murine development and homeostasis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.470476

21 January 2018

Stabilization of integrin-linked kinase by binding to Hsp90.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.470476

21 January 2018

Bypass of lethality with mosaic mice generated by Cre– loxP -mediated recombination

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M113.470476

21 January 2018

Identifiers

10.1074/JBC.M113.470476

0 references

PMC publication ID

0 references

PubMed publication ID

1 reference

PubMed publication ID

24 January 2017

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