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Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
title
Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine
(English)
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
main subject
enterocyte differentiation
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:1903703
PTK6 protein tyrosine kinase 6
1 reference
stated in
GOA release 2020-03-11
author
Elaine Fuchs
series ordinal
6
object named as
Elaine Fuchs
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
Valeri Vasioukhin
object named as
Valeri Vasioukhin
series ordinal
5
1 reference
stated in
ORCID Public Data File 2021
Angela L. Tyner
series ordinal
7
object named as
Angela L. Tyner
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
author name string
Andrea Haegebarth
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
Wenjun Bie
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
Ruyan Yang
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
Susan E. Crawford
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
language of work or name
English
0 references
publication date
1 July 2006
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
published in
Molecular and Cellular Biology
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
volume
26
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
issue
13
1 reference
stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
page(s)
4949–4957
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stated in
PubMed
PubMed ID
16782882
retrieved
24 January 2017
cites work
Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Regulated association of protein kinase B/Akt with breast tumor kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
A novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRK
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
BRK/Sik expression in the gastrointestinal tract and in colon tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Generalized lacZ expression with the ROSA26 Cre reporter strain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Rak, a novel nuclear tyrosine kinase expressed in epithelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
19 March 2017
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
7 April 2017
Mechanisms of enteral nutrient-enhanced intestinal adaptation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
The Akt-mTOR tango and its relevance to cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Role of breast tumour kinase in the in vitro differentiation of HaCaT cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Wnt signaling in the intestinal epithelium: from endoderm to cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Self-renewal and cancer of the gut: two sides of a coin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Differential expression of the non-receptor tyrosine kinase BRK in oral squamous cell carcinoma and normal oral epithelium.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Proteomic analysis identifies that 14-3-3zeta interacts with beta-catenin and facilitates its activation by Akt.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
The Brk protein tyrosine kinase as a therapeutic target in cancer: opportunities and challenges
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
The many forks in FOXO's road
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Breast cancer cell line proliferation blocked by the Src-related Rak tyrosine kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Intracellular lipid binding proteins of the small intestine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Akt participation in the Wnt signaling pathway through Dishevelled
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
A genetic screen for modifiers of drosophila Src42A identifies mutations in Egfr, rolled and a novel signaling gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Tyrosine kinase gene expression in the mouse small intestine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Cellular differentiation in the emerging fetal rat small intestinal epithelium: mosaic patterns of gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
29 September 2017
Drosophila Src42A is a negative regulator of RTK signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
2 June 2018
Targeted intestinal overexpression of the immediate early gene tis7 in transgenic mice increases triglyceride absorption and adiposity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
27 November 2018
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
27 November 2018
Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
27 November 2018
The intestinal fatty acid binding protein is not essential for dietary fat absorption in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1489160
retrieved
27 November 2018
Enterocytic gene expression in intestinal adaptation: evidence for a specific cellular response
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16782882
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
BRK tyrosine kinase expression in a high proportion of human breast carcinomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16782882
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.01901-05
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
744560
OpenCitations bibliographic resource ID
744560
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
744560
PMCID
1489160
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
744560
PubMed ID
16782882
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
744560
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