(Q28509829)

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Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease

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24 January 2017

Europe PubMed Central

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25 February 2020

Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease (English)

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23469164%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Intraflagellar transport 140

1 reference

GOA release 2020-03-11

Fraser extracellular matrix complex subunit 1

1 reference

GOA release 2020-03-11

Megan J. Wallace

5

1 reference

Europe PubMed Central

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25 February 2020

Christopher T Gordon

7

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25 February 2020

8

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25 February 2020

Vincent R Harley

13

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25 February 2020

John F. Bertram

15

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25 February 2020

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Georgina Caruana

1

2 references

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24 January 2017

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25 February 2020

Stefan Bagheri-Fam

4

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

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25 February 2020

Belinda Whittle

9

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

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25 February 2020

Peter G Farlie

2

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25 February 2020

Adam H Hart

3

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25 February 2020

Michael S Dobbie

6

1 reference

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25 February 2020

Helen E Abud

10

1 reference

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25 February 2020

Ruth M Arkell

11

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25 February 2020

Timothy J Cole

12

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25 February 2020

Ian M Smyth

14

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25 February 2020

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1 March 2013

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25 February 2020

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23469164%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

8

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23469164%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

3

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

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25 February 2020

e55429

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

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25 February 2020

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Creative Commons Attribution 4.0 International

1 March 2013

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April 2022 Public Data File from Crossref

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0 references

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking

1 reference

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Mainzer-Saldino syndrome is a ciliopathy caused by IFT140 mutations

1 reference

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Summarizing and correcting the GC content bias in high-throughput sequencing

1 reference

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Mutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathies

1 reference

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19 March 2017

Subunit interactions and organization of the Chlamydomonas reinhardtii intraflagellar transport complex A proteins

1 reference

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19 March 2017

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome

1 reference

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Tulp3 is a critical repressor of mouse hedgehog signaling

1 reference

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19 March 2017

Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway

1 reference

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19 March 2017

Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

Intraflagellar transport (IFT) role in ciliary assembly, resorption and signalling.

1 reference

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A Sox10 expression screen identifies an amino acid essential for Erbb3 function

1 reference

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19 March 2017

A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy

1 reference

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19 March 2017

Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

The genetics of Fraser syndrome and the blebs mouse mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

Homozygous inactivation of Sox9 causes complete XY sex reversal in mice

1 reference

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19 March 2017

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

1 reference

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19 March 2017

Analysis of mouse embryonic patterning and morphogenesis by forward genetics

1 reference

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19 March 2017

Human DNA ligase I completely encircles and partially unwinds nicked DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

New semidominant mutations that affect mouse development

1 reference

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19 March 2017

Functional genetic analysis of mouse chromosome 11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

A phenotype-based screen for embryonic lethal mutations in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

19 March 2017

Potential and limitations of genetic manipulation in animals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Multiplex Chromosomal Exome Sequencing Accelerates Identification of ENU-Induced Mutations in the Mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Cytopenia induction by 5-fluorouracil identifies thrombopoietic mutants in sensitized ENU mutagenesis screens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Mutation discovery in mice by whole exome sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Random mutagenesis of the mouse genome: a strategy for discovering gene function and the molecular basis of disease

1 reference

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29 September 2017

Genome-wide identification of mouse congenital heart disease loci

1 reference

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29 September 2017

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

1 reference

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29 September 2017

A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines.

1 reference

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Renal tract malformations: perspectives for nephrologists

1 reference

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microMRI-HREM pipeline for high-throughput, high-resolution phenotyping of murine embryos

1 reference

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29 September 2017

Sex determination and gonadal development in mammals

1 reference

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29 September 2017

The use of genomewide ENU mutagenesis screens to unravel complex mammalian traits: identifying genes that regulate organ-specific and systemic autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Role of the physicochemical environment in lung development

1 reference

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29 September 2017

Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Implementing large-scale ENU mutagenesis screens in North America

1 reference

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29 September 2017

Evolving concepts in human renal dysplasia

1 reference

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29 September 2017

A genomewide screening of N-ethyl-N-nitrosourea-mutagenized mice for musculoskeletal phenotypes☆

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein

1 reference

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Paradigm shift from classic anatomic theories to contemporary cell biological views of CAKUT.

1 reference

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29 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

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1 reference

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29 September 2017

Mouse ENU mutagenesis

1 reference

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29 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

29 September 2017

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1 reference

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1 reference

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29 September 2017

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1 reference

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1 reference

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21 January 2018

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1 reference

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27 November 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

27 November 2018

Mouse mutagenesis identifies novel roles for left-right patterning genes in pulmonary, craniofacial, ocular, and limb development

1 reference

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27 November 2018

Novel lethal mouse mutants produced in balancer chromosome screens.

1 reference

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27 November 2018

A repository of ENU mutant mouse lines and their potential for male fertility research

1 reference

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27 November 2018

ENU induced mutations causing congenital cardiovascular anomalies

1 reference

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27 November 2018

Mutations in a novel locus on mouse chromosome 11 resulting in male infertility associated with defects in microtubule assembly and sperm tail function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585849

27 November 2018

Complications and long-term outcome of primary obstructive megaureter in childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/23469164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards a mutant map of the mouse--new models of neurological, behavioural, deafness, bone, renal and blood disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/23469164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0055429

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23469164%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

2013PLoSO...855429C

0 references

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23469164%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23469164%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

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