(Q28510294)

Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway

GOA release 2020-03-11

1 reference

4

Philip J. Gage

1 reference

25 January 2017

6

Judith A. West-Mays

1 reference

25 January 2017

Erin A. Bassett

1

1 reference

25 January 2017

Trevor Williams

series ordinal

2

1 reference

25 January 2017

Amanda L. Zacharias

series ordinal

3

1 reference

25 January 2017

Sabine Fuhrmann

series ordinal

5

1 reference

25 January 2017

language of work or name

1 reference

1 May 2010

1 reference

25 January 2017

Human Molecular Genetics

1 reference

25 January 2017

19

1 reference

25 January 2017

9

1 reference

25 January 2017

1791–1804

1 reference

25 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

TFAP2A mutations result in branchio-oculo-facial syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Complementary Gli activity mediates early patterning of the mouse visual system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Targeted deletion of AP-2alpha leads to disruption in corneal epithelial cell integrity and defects in the corneal stroma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Magnitude of binocular vision controlled by islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Requirement for AP-2alpha in cardiac outflow tract morphogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

The subcellular localization of Otx2 is cell-type specific and developmentally regulated in the mouse retina

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Dosage requirement of Pitx2 for development of multiple organs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Altered neural cell fates and medulloblastoma in mouse patched mutants

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Pax2 contributes to inner ear patterning and optic nerve trajectory

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Transcription factor AP-2 essential for cranial closure and craniofacial development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Expression of a Delta homologue in prospective neurons in the chick

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Signaling "cross-talk" is integrated by transcription factors in the development of the anterior segment in the eye.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Molecular and developmental mechanisms of anterior segment dysgenesis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Molecular mechanisms of optic vesicle development: complexities, ambiguities and controversies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Lens induction in vertebrates: variations on a conserved theme of signaling events

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Eye development: a view from the retina pigmented epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Roles of cell-extrinsic growth factors in vertebrate eye pattern formation and retinogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Wnt1-Cre-mediated deletion of AP-2alpha causes multiple neural crest-related defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Early steps in the development of the forebrain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Positive influence of AP-2alpha transcription factor on cadherin gene expression and differentiation of the ocular surface

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Early eye development in vertebrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Mini-review: toward understanding mechanisms of genetic neural tube defects in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Mouse patched1 controls body size determination and limb patterning.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Dorsal-ventral patterning defects in the eye of BF-1-deficient mice associated with a restricted loss of shh expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Pax2 expression and retinal morphogenesis in the normal and Krd mouse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Sonic hedgehog: a common signal for ventral patterning along the rostrocaudal axis of the neural tube.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Further delineation of the branchio-oculo-facial syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

The branchio-oculo-facial syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Sclerocornea and interstitial deletion of the short arm of chromosome 6--(46XY del[6] [p22 p24])

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Investigation of Frizzled-5 during embryonic neural development in mouse

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Functional roles of Otx2 transcription factor in postnatal mouse retinal development.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Dorsal and lateral fates in the mouse neural tube require the cell-autonomous activity of the open brain gene

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

An interstitial deletion of 6p24-p25 proximal to the FKHL7 locus and including AP-2alpha that affects anterior eye chamber development

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Delineation of two distinct 6p deletion syndromes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Patterning of the embryonic forebrain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Vital dye analysis of cranial neural crest cell migration in the mouse embryo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Studies on the development of the eye cup and optic nerve in normal mice and in mutants with congenital optic nerve aplasia

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Fate maps of neural crest and mesoderm in the mammalian eye.

2 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Hedgehog signalling maintains the optic stalk-retinal interface through the regulation of Vax gene activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Confirmation of TFAP2A gene involvement in branchio-oculo-facial syndrome (BOFS) and report of temporal bone anomalies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Ectopic expression of AP-2alpha transcription factor in the lens disrupts fiber cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Comparative analysis of AP-2 alpha and AP-2 beta gene expression during murine embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Transient overexpression of the Microphthalmia gene in the eyes of Microphthalmia vitiligo mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Apoptosis in early ocular morphogenesis in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Apoptosis in mammalian eye development: lens morphogenesis, vascular regression and immune privilege.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Hedgehog signalling controls eye degeneration in blind cavefish

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Impairing retinoic acid signalling in the neural crest cells is sufficient to alter entire eye morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDQ060

Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Mosaics of islet-1-expressing amacrine cells assembled by short-range cellular interactions.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Midline signalling is required for Pax gene regulation and patterning of the eyes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2850623

Spatially and temporally restricted expression of Pax2 during murine neurogenesis

27 November 2018

1 reference

12 December 2020

The role of cell death during morphogenesis of the mammalian eye

1 reference

12 December 2020

Macrophages during retina and optic nerve development in the mouse embryo: relationship to cell death and optic fibres

1 reference

12 December 2020

FGF1 patterns the optic vesicle by directing the placement of the neural retina domain

1 reference

12 December 2020

Extraocular mesenchyme patterns the optic vesicle during early eye development in the embryonic chick

1 reference

12 December 2020

Optic fissure closure in the normal cinnamon mouse. An ultrastructural study

1 reference

12 December 2020

Otx genes are required for tissue specification in the developing eye

1 reference

12 December 2020

Cytoplasmic processes interconnect lens placode and optic vesicle during eye morphogenesis

1 reference

12 December 2020

Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube

1 reference

12 December 2020

Cephalic neurulation and optic vesicle formation in the early mouse embryo

1 reference

12 December 2020

A complexTFAP2Aallele is associated with branchio-oculo-facial syndrome and inner ear malformation in a deaf child

1 reference

12 December 2020