(Q28510984)

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Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death

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25 January 2017

Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death (English)

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25 January 2017

Hypoxia inducible factor 1, alpha subunit

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stated in

GOA release 2020-03-11

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4

G. L. Semenza

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25 January 2017

L. E. Kotch

1

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25 January 2017

N. V. Iyer

series ordinal

2

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25 January 2017

E. Laughner

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3

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25 January 2017

language of work or name

English

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publication date

15 May 1999

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25 January 2017

Developmental Biology

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25 January 2017

209

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25 January 2017

254–267

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25 January 2017

2

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25 January 2017

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

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Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

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Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia.

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Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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Vascular endothelial growth factor induces heparin-binding epidermal growth factor-like growth factor in vascular endothelial cells

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Migration of cranial neural crest cells to the pharyngeal arches and heart in rat embryos

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

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Post-transcriptional regulation of vascular endothelial growth factor by hypoxia.

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Vascular development: cellular and molecular regulation.

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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Cardiac neural crest is essential for the persistence rather than the formation of an arch artery

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Neovascularization and the appearance of morphological characteristics of the blood-brain barrier in the embryonic mouse central nervous system

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A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

1 reference

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

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Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

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Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells.

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

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Pericyte-endothelial gap junctions in developing rat cerebral capillaries: a fine structural study

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Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

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Purification and characterization of hypoxia-inducible factor 1

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Hypoxia-inducible factor 1: master regulator of O2 homeostasis

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(Q28510984)

Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death

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