(Q28511479)

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

Rabaptin, RAB GTPase binding effector protein 1

1 reference

GOA release 2020-03-11

Early endosome antigen 1

1 reference

GOA release 2020-03-11

1 reference

1 reference

8

Matthias Staufenbiel

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

Suzana Petanceska

2

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Angela Villar

6

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Anne M Cataldo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Corrinne M Peterhoff

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Nicole B Terio

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Charles J Epstein

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Elaine J Carlson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Ralph A Nixon

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

1 July 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

published in

Journal of Neuroscience

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

23

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

17

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

6788-6792

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

The neural mechanisms underlying cholinergic cell death within the basal forebrain

6 November 2019

cites work

1 reference

12 December 2020

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

12 December 2020

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

1 reference

12 December 2020

Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase

1 reference

12 December 2020

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

12 December 2020

Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders

1 reference

12 December 2020

Elevated expression of beta-site amyloid precursor protein cleaving enzyme 2 in brains of patients with Down syndrome

1 reference

12 December 2020

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

1 reference

12 December 2020

The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway

1 reference

12 December 2020

Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome

1 reference

12 December 2020

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

1 reference

12 December 2020

Gene encoding the beta subunit of S100 protein is on chromosome 21: implications for Down syndrome

1 reference

12 December 2020

A mouse model for Down syndrome exhibits learning and behaviour deficits.

1 reference

12 December 2020

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion

1 reference

12 December 2020

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

1 reference

12 December 2020

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

1 reference

12 December 2020

Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha+ microglia and S100beta+ astrocytes with neurofibrillary tangle stages.

1 reference

12 December 2020

Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis

1 reference

12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

12 December 2020

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

12 December 2020

Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion

1 reference

12 December 2020

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

1 reference

12 December 2020

Life-long overexpression of S100beta in Down's syndrome: implications for Alzheimer pathogenesis

1 reference

12 December 2020

10.1523/JNEUROSCI.23-17-06788.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12890772%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

2 references

25 January 2017