(Q28512139)

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11 (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

SPG11, spatacsin vesicle trafficking associated

22 February 2020

main subject

1 reference

Sequestosome 1

1 reference

Microtubule-associated protein 1 light chain 3 beta

1 reference

Lysosomal-associated membrane protein 1

1 reference

hereditary spastic paraplegia

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Thomas Jentsch

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Britta Qualmann

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Ingo Kurth

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Christian Beetz

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

11

Michael M Kessels

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

7

Nicole Koch

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

18

Christian A Hübner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

10

Antje K Huebner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Rita-Eva Varga

1

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Mukhran Khundadze

2

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Markus Damme

3

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Sandor Nietzsche

4

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Birgit Hoffmann

5

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Patricia Franzka

9

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Christoph Biskup

12

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Thomas Braulke

15

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

J Christopher Hennings

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

publication date

18 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

11

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

8

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

e1005454

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

22 February 2020

copyright license

start time

18 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4540459/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Dysfunction of spatacsin leads to axonal pathology in SPG11-linked hereditary spastic paraplegia

1 reference

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Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders

19 March 2017

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A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system

19 March 2017

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Adaptor protein complexes AP-4 and AP-5: new players in endosomal trafficking and progressive spastic paraplegia

19 March 2017

1 reference

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19 March 2017

1 reference

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A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia

19 March 2017

1 reference

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PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

19 March 2017

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Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

19 March 2017

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

19 March 2017

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

19 March 2017

1 reference

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Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

19 March 2017

1 reference

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Autophagy: renovation of cells and tissues

19 March 2017

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Termination of autophagy and reformation of lysosomes regulated by mTOR

7 April 2017

1 reference

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Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation

7 April 2017

1 reference

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Hereditary spastic paraplegia: clinical principles and genetic advances

29 September 2017

1 reference

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Lysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11.

29 September 2017

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At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy.

29 September 2017

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Molecular logic of neocortical projection neuron specification, development and diversity

29 September 2017

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A spastic paraplegia mouse model reveals REEP1-dependent ER shaping.

29 September 2017

1 reference

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Defective autophagy in spastizin mutated patients with hereditary spastic paraparesis type 15

29 September 2017

1 reference

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Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule

29 September 2017

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29 September 2017

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29 September 2017

1 reference

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29 September 2017

1 reference

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Identification of the SPG15 gene, encoding spastizin, as a frequent cause of complicated autosomal-recessive spastic paraplegia, including Kjellin syndrome

29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

29 September 2017

1 reference

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29 September 2017

1 reference

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Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold

29 September 2017

1 reference

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29 September 2017

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Mutations in SPG11, encoding spatacsin, are a major cause of spastic paraplegia with thin corpus callosum

21 January 2018

1 reference

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Spatacsin and spastizin act in the same pathway required for proper spinal motor neuron axon outgrowth in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

Deficiency of corpus callosum varies with strain and supplier of the mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

Neurogenic mechanisms contribute to hypertension in mice with disruption of the K-Cl cotransporter KCC3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

BioImageXD: an open, general-purpose and high-throughput image-processing platform.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1005454

10.1371/JOURNAL.PGEN.1005454

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26284655%20AND%20SRC:MED&resulttype=core&format=json