(Q28513821)

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Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function

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scholarly article

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PubMed publication ID

25 January 2017

Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function (English)

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

Leukemia inhibitory factor

1 reference

GOA release 2020-03-11

Ciliary neurotrophic factor

1 reference

GOA release 2020-03-11

Cardiotrophin 1

1 reference

GOA release 2020-03-11

Michael Sendtner

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

4

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Katja Grohmann

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

Bettina Holtmann

1

object named as

Bettina Holtmann

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

2

object named as

Stefan Wiese

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

author name string

Mohtashem Samsam

3

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

Diane Pennica

5

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

16 February 2005

1 reference

PubMed publication ID

25 January 2017

Journal of Neuroscience

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

25

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

7

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

1778-1787

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

Development of the vertebrate neuromuscular junction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suckling defect in mice lacking the soluble haemopoietin receptor NR6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia Inhibitory Factor Is an Autocrine Survival Factor for Schwann Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computational EST database analysis identifies a novel member of the neuropoietic cytokine family

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of macrophages in demyelinating peripheral nervous system of mice heterozygously deficient in p0.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of myelinating Schwann cells on axons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor determines the growth status of injured adult sensory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction, assembly, maturation and maintenance of a postsynaptic apparatus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of leukemia inhibitory factor in human nerve following injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNTF is a major protective factor in demyelinating CNS disease: A neurotrophic cytokine as modulator in neuroinflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early onset of degenerative changes at nodes of Ranvier in alpha-motor axons of Cntf null (-/-) mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple cholinergic differentiation factors are present in footpad extracts: comparison with known cholinergic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiotrophin-Like Cytokine/Cytokine-Like Factor 1 is an Essential Trophic Factor for Lumbar and Facial MotoneuronsIn Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunolocalization of ciliary neuronotrophic factor in adult rat sciatic nerve

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant cholinergic differentiation factor (leukemia inhibitory factor) regulates sympathetic neuron phenotype by alterations in the size and amounts of neuropeptide mRNAs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cholinergic neuronal differentiation factor from heart cells is identical to leukemia inhibitory factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential function of LIF receptor in motor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor mediates an injury response but not a target-directed developmental transmitter switch in sympathetic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrograde axonal transport of LIF is increased by peripheral nerve injury: correlation with increased LIF expression in distal nerve

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking the CNTF receptor, unlike mice lacking CNTF, exhibit profound motor neuron deficits at birth

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major changes in the expression of the mRNAs for cholinergic differentiation factor/leukemia inhibitory factor and its receptor after injury to adult peripheral nerves and ganglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Members of several gene families influence survival of rat motoneurons in vitro and in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the CNTF gene results in motor neuron degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal differentiation factors/cytokines and synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukaemia inhibitory factor is necessary for maintenance of haematopoietic stem cells and thymocyte stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor influences the timing of programmed synapses withdrawal from neonatal muscles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective neuromuscular synaptogenesis in agrin-deficient mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signals triggering the induction of leukemia inhibitory factor in sympathetic superior cervical ganglia and their nerve trunks after axonal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukemia inhibitory factor enhances the regeneration of transected rat sciatic nerve and the function of reinnervated muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNTF and LIF are not required for the target-directed acquisition of cholinergic and peptidergic properties by sympathetic neurons in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe neuropathies in mice with targeted mutations in the ErbB3 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schwann cells express NDF and SMDF/n-ARIA mRNAs, secrete neuregulin, and show constitutive activation of erbB3 receptors: evidence for a neuregulin autocrine loop

1 reference

https://pubmed.ncbi.nlm.nih.gov/15716414

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4249-04.2005

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

PubMed publication ID

2 references

PubMed publication ID

25 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725944&resulttype=core&format=json

12 May 2020

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