(Q28534312)

English

IL-6 regulates Mcl-1L expression through the JAK/PI3K/Akt/CREB signaling pathway in hepatocytes: implication of an anti-apoptotic role during liver regeneration

scientific article (publication date: 2013)

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scholarly article

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IL-6 regulates Mcl-1L expression through the JAK/PI3K/Akt/CREB signaling pathway in hepatocytes: implication of an anti-apoptotic role during liver regeneration (English)

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apoptotic process

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4

object named as

Po-Huang Lee

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object named as

Fu-Chuo Peng

5

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Chiung-Nien Chen

object named as

Chiung-Nien Chen

3

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object named as

Min-Liang Kuo

6

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object named as

Hong-Shiee Lai

7

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author name string

Chia-Hung Chou

1

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Shuo-Lun Lai

2

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language of work or name

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publication date

2013

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8

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6

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e66268

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copyright license

Creative Commons Attribution 4.0 International

25 June 2013

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April 2022 Public Data File from Crossref

copyright status

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Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

19 March 2017

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

19 March 2017

Carfilzomib and ONX 0912 inhibit cell survival and tumor growth of head and neck cancer and their activities are enhanced by suppression of Mcl-1 or autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Sabutoclax, a Mcl-1 antagonist, inhibits tumorigenesis in transgenic mouse and human xenograft models of prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Oncostatin m renders epithelial cell adhesion molecule-positive liver cancer stem cells sensitive to 5-Fluorouracil by inducing hepatocytic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Hepatocyte-specific deletion of the antiapoptotic protein myeloid cell leukemia-1 triggers proliferation and hepatocarcinogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

BH3-only protein bid participates in the Bcl-2 network in healthy liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Impact of interleukin-6 classic- and trans-signaling on liver damage and regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Flavopiridol causes early mitochondrial damage in chronic lymphocytic leukemia cells with impaired oxygen consumption and mobilization of intracellular calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Oncostatin M gene therapy attenuates liver damage induced by dimethylnitrosamine in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Interleukin-6 and its receptor: from bench to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

The anti-apoptotic protein Mcl-1 inhibits mitochondrial Ca2+ signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Liver regeneration: from myth to mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Mechanism of liver regeneration after partial hepatectomy using mouse cDNA microarray

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

29 September 2017

Association of anti-apoptotic Mcl-1L isoform expression with radioresistance of oral squamous carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

2 June 2018

Pim-3 protects against hepatic failure in D-galactosamine (D-GalN)-sensitized rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

2 June 2018

Autonomic regulation of liver regeneration after partial hepatectomy in mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Liver regeneration

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Interleukin-6 from intrahepatic cells of bone marrow origin is required for normal murine liver regeneration.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Role of IL-6 trans-signaling in CCl₄induced liver damage

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Activation of human liver sinusoidal endothelial cell by human platelets induces hepatocyte proliferation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Radiation-induced interleukin-6 expression through MAPK/p38/NF-kappaB signaling pathway and the resultant antiapoptotic effect on endothelial cells through Mcl-1 expression with sIL6-Ralpha

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Role of interleukin-6 in the control of DNA synthesis of hepatocytes: involvement of PKC, p44/42 MAPKs, and PPARdelta.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0066268

21 January 2018

Variations in interferon gamma receptor gene expression during liver regeneration after partial hepatectomy in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3692501

27 November 2018

Liver regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23825534

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase activation is associated with spontaneous recovery from acute liver failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23825534

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Portal vein arterialization increases hepatocellular apoptosis and inhibits liver regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23825534

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-alpha and IL-6 signals from the bone marrow derived cells are necessary for normal murine liver regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23825534

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0066268

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2013PLoSO...866268C

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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