(Q28535420)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

GOA release 2020-03-11

SMAD specific E3 ubiquitin protein ligase Dmel_CG4943

1 reference

GOA release 2020-03-11

author

Xiudeng Zheng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Yi Tao

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Feng Liu

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Shoujun Huang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Zhao Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Chunxia Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Xiangdong Lv

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Zhenping Chen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Liwei Sun

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Hailong Wang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Yuanxiang Zhu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Jing Zhang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Shuyan Yang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Yi Lu

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Qinmiao Sun

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Yun Zhao

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Dahua Chen

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

26 November 2013

1 reference

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2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

page(s)

e1001721

1 reference

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Creative Commons Attribution 3.0 Unported

2 March 2020

copyright license

start time

26 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Ter94 ATPase complex targets k11-linked ubiquitinated ci to proteasomes for partial degradation

1 reference

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19 March 2017

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Dynamic interpretation of hedgehog signaling in the Drosophila wing disc

19 March 2017

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LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

19 March 2017

1 reference

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Regulation of planar cell polarity by Smurf ubiquitin ligases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

WW and SH3 domains, two different scaffolds to recognize proline-rich ligands

19 March 2017

1 reference

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Hedgehog signaling in animal development: paradigms and principles

19 March 2017

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Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

19 March 2017

1 reference

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

19 March 2017

1 reference

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Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome

19 March 2017

1 reference

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Dual roles for patched in sequestering and transducing Hedgehog

19 March 2017

1 reference

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Physiological functions of the HECT family of ubiquitin ligases

19 March 2017

1 reference

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Patched dependence receptor triggers apoptosis through ubiquitination of caspase-9.

7 April 2017

1 reference

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USP8 promotes smoothened signaling by preventing its ubiquitination and changing its subcellular localization

29 September 2017

1 reference

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A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20.

29 September 2017

1 reference

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Ihog and Boi are essential for Hedgehog signaling in Drosophila.

29 September 2017

1 reference

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Genetic and biochemical definition of the Hedgehog receptor

29 September 2017

1 reference

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The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates

29 September 2017

1 reference

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Temporal dynamics of patterning by morphogen gradients

29 September 2017

1 reference

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Hedgehog signaling in development and cancer.

29 September 2017

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The HECT family of E3 ubiquitin ligases: multiple players in cancer development

29 September 2017

1 reference

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Hedgehog regulates smoothened activity by inducing a conformational switch

29 September 2017

1 reference

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Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Negative regulation of TGF-beta receptor/Smad signal transduction.

29 September 2017

1 reference

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The hedgehog signaling pathway in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Hedgehog signalling in skin development and cancer

29 September 2017

1 reference

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Degradation of RhoA by Smurf1 ubiquitin ligase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

The interpretation of morphogen gradients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Communicating with Hedgehogs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Morphogen gradient interpretation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

The Drosophila patched gene encodes a putative membrane protein required for segmental patterning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

The Fused/Smurf complex controls the fate of Drosophila germline stem cells by generating a gradient BMP response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Two patched protein subtypes and a conserved domain of group I proteins that regulates turnover

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Activation of knot (kn) specifies the 3-4 intervein region in the Drosophila wing.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

Protein kinase A and hedgehog signaling in Drosophila limb development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

3 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

dSmurf Selectively Degrades Decapentaplegic-activated MAD, and Its Overexpression Disrupts Imaginal Disc Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

The niche-dependent feedback loop generates a BMP activity gradient to determine the germline stem cell fate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

Gene circuitry controlling a stem cell niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

Self-Induced Patched Receptor Down-Regulation Modulates Cell Sensitivity to the Hedgehog Morphogen Gradient

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

Effete-mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

Effective gene silencing in Drosophila ovarian germline by artificial microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

Reading the Hedgehog morphogen gradient by measuring the ratio of bound to unbound Patched protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

Otefin, a nuclear membrane protein, determines the fate of germline stem cells in Drosophila via interaction with Smad complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001721

In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3841102

10.1371/JOURNAL.PBIO.1001721

27 November 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

24302888

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24302888%20AND%20SRC:MED&resulttype=core&format=json