(Q28537694)

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Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

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Europe PubMed Central

PubMed publication ID

21 June 2017

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing (English)

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21 June 2017

anti-retroviral agent

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Jeffrey P Murry

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Jeffrey P Murry

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Mary Kearney

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Tomáš Cihlář

22

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Tomas Cihlar

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21 June 2017

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John Mellors

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21 June 2017

Jonathan Spindler

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Jonathan Spindler

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21 June 2017

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Datsen George Wei

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21 June 2017

Vicki Chiang

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21 June 2017

Elizabeth Fyne

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21 June 2017

Mini Balakrishnan

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21 June 2017

Tiffany Barnes

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21 June 2017

Michael Graupe

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21 June 2017

Joseph Hesselgesser

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21 June 2017

Alivelu Irrinki

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21 June 2017

George Stepan

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21 June 2017

Kirsten M Stray

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21 June 2017

Angela Tsai

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21 June 2017

Helen Yu

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21 June 2017

Celsa A Spina

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21 June 2017

Deborah McMahon

17

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21 June 2017

Jacob Lalezari

18

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21 June 2017

Derek Sloan

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21 June 2017

Romas Geleziunas

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21 June 2017

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publication date

10 April 2014

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21 June 2017

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21 June 2017

10

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21 June 2017

4

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21 June 2017

e1004071

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Europe PubMed Central

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21 June 2017

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Creative Commons CC0 License

10 April 2014

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April 2022 Public Data File from Crossref

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copyrighted, dedicated to the public domain by copyright holder

0 references

HIV-1 eradication strategies: design and assessment

1 reference

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19 March 2017

Redefining the viral reservoirs that prevent HIV-1 eradication

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19 March 2017

Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

19 March 2017

Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies

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19 March 2017

Randomized, controlled trial of therapy interruption in chronic HIV-1 infection

1 reference

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19 March 2017

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

7 April 2017

Histone deacetylase inhibitor suppresses virus-induced proinflammatory responses and type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Altering cell death pathways as an approach to cure HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

High levels of CD2 expression identify HIV-1 latently infected resting memory CD4+ T cells in virally suppressed subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Monoclonal antibodies in oncology therapeutics: present and future indications

1 reference

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29 September 2017

Suberoylanilide hydroxamic acid induces limited changes in the transcriptome of primary CD4(+) T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Immunomodulatory effects of histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Antibody-dependent cellular cytotoxicity against primary HIV-infected CD4+ T cells is directly associated with the magnitude of surface IgG binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

The histone deacetylase inhibitor, romidepsin, suppresses cellular immune functions of cutaneous T-cell lymphoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

HDAC inhibitors in HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Romidepsin: a novel histone deacetylase inhibitor for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Phase 2 trial of romidepsin in patients with peripheral T-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Combinatorial latency reactivation for HIV-1 subtypes and variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Understanding HIV-1 latency provides clues for the eradication of long-term reservoirs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Short communication: activation of latent HIV type 1 gene expression by suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor approved for use to treat cutaneous T cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

The latent reservoir for HIV-1 in resting CD4+ T cells: a barrier to cure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

The challenge of finding a cure for HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Effective therapy has altered the spectrum of cause-specific mortality following HIV seroconversion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

29 September 2017

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

1 reference

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29 September 2017

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.

1 reference

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3 June 2018

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

1 reference

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3 June 2018

c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

3 June 2018

NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation

1 reference

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3 June 2018

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21 January 2018

Once-daily dolutegravir versus raltegravir in antiretroviral-naive adults with HIV-1 infection: 48 week results from the randomised, double-blind, non-inferiority SPRING-2 study

1 reference

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21 January 2018

Relationship between pre-existing viral reservoirs and the re-emergence of plasma viremia after discontinuation of highly active anti-retroviral therapy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004071

21 January 2018

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

1 reference

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21 January 2018

Combination antiretroviral therapy and the risk of myocardial infarction

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1 reference

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21 January 2018

Histone deacetylase inhibitors impair antibacterial defenses of macrophages.

1 reference

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21 January 2018

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3983056

27 November 2018

Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/24722454

12 December 2020

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inferred from PubMed ID database lookup

Epigenetic regulation of the innate immune response to LPS in bovine peripheral blood mononuclear cells (PBMC)

1 reference

https://pubmed.ncbi.nlm.nih.gov/24722454

12 December 2020

based on heuristic

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10.1371/JOURNAL.PPAT.1004071

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Europe PubMed Central

PubMed publication ID

21 June 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

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21 June 2017

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