(Q28558029)

Zinc finger, NHR/GATA-type

1 reference

glucocorticoid receptor

1 reference

Nuclear hormone receptor, ligand-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, nuclear hormone receptor-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

17 November 2021

1 reference

17 November 2021

2 references

1 reference

14 February 2019

GR and HMGB1 interact only within chromatin and influence each other's residence time

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

double-stranded DNA binding

1 reference

14 February 2019

Steroid receptor heterodimerization demonstrated in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

steroid hormone receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

transcription coactivator activity

1 reference

14 February 2019

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

nuclear receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

glucocorticoid receptor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

3 references

14 February 2019

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

9 references

14 February 2019

BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

Glucocorticoid-mediated suppression of cytokine-induced matrix metalloproteinase-9 expression in rat mesangial cells: involvement of nuclear factor-kappaB and Ets transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

GR and HMGB1 interact only within chromatin and influence each other's residence time

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

Proteomic identification of glucocorticoid receptor interacting proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

PA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

Glucocorticoid receptor interaction with TrkB promotes BDNF-triggered PLC-gamma signaling for glutamate release via a glutamate transporter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

transcription factor binding

IPI

1 reference

14 February 2019

Association of the glucocorticoid receptor with STAT3, C/EBPbeta, and the hormone-responsive element within the rat haptoglobin gene promoter during the acute phase response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

Interaction of rat renal glucocorticoid receptor with Hsp90 and Hsp70 upon stress provoked by mercury

Hsp70 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

receptor tyrosine kinase binding

1 reference

14 February 2019

FMS-like tyrosine kinase 3 interacts with the glucocorticoid receptor complex and affects glucocorticoid dependent signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

heat shock protein binding

IPI

1 reference

14 February 2019

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Role of macrophage migration inhibitory factor in glucocorticoid release and glucocorticoid receptor function in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

protein homodimerization activity

IPI

1 reference

14 February 2019

Steroid receptor heterodimerization demonstrated in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

Steroid receptor heterodimerization demonstrated in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

protein-containing complex binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

protein heterodimerization activity

1 reference

14 February 2019

Steroid receptor heterodimerization demonstrated in vitro and in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

protein dimerization activity

1 reference

14 February 2019

Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA bin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

Interaction of rat renal glucocorticoid receptor with Hsp90 and Hsp70 upon stress provoked by mercury

TAS

Hsp90 protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

steroid hormone binding

1 reference

14 February 2019

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

The aldosterone-mineralocorticoid receptor pathway exerts anti-inflammatory effects in endotoxin-induced uveitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

microtubule organizing center

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Localization of mineralocorticoid receptors at mammalian synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

protein-containing complex

1 reference

14 February 2019

Cytosolic glucocorticoid receptor interaction with nuclear factor-kappa B proteins in rat liver cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Localization of mineralocorticoid receptors at mammalian synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

Localization of mineralocorticoid receptors at mammalian synapses

glutamatergic synapse

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

postsynaptic density, intracellular component

1 reference

14 February 2019

Localization of mineralocorticoid receptors at mammalian synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

biological process

chromatin organization

1 reference

14 February 2019

1 reference

14 February 2019

BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Glucocorticoid receptor expression in the cortex of the neonatal rat brain with and without focal cerebral ischemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Expression of glucocorticoid receptor and glucose transporter-1 during placental development in the diabetic rat.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Glucocorticoid receptor changes associate with age in the paraventricular nucleus of type II diabetic rat model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Modeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

androgen metabolic process

1 reference

14 February 2019

Androgens modulate glucocorticoid receptor mRNA, but not mineralocorticoid receptor mRNA levels, in the rat hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

Effects of electromagnetic irradiation on glucocorticoid in serum and its receptor expression in rat hippocampus

response to radiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

regulation of glucose metabolic process

1 reference

14 February 2019

Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

positive regulation of glutamate secretion

1 reference

14 February 2019

Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Changes of cytosol glucocorticoid receptor and renal Na(+)-K(+)-ATPase activity after swimming training in rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

Casted-immobilization downregulates glucocorticoid receptor expression in rat slow-twitch soleus muscle

response to inactivity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Transcription factors in muscle atrophy caused by blocked neuromuscular transmission and muscle unloading in rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Modeling glucocorticoid-mediated fetal lung maturation: II. Temporal patterns of gene expression in fetal rat lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

negative regulation of synaptic plasticity

1 reference

14 February 2019

Acute stress, but not corticosterone, disrupts short- and long-term synaptic plasticity in rat dorsal subiculum via glucocorticoid receptor activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

1 reference

14 February 2019

Insulin modulates rat liver glucocorticoid receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

regulation of cell population proliferation

1 reference

14 February 2019

Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

glucocorticoid receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

negative regulation of apoptotic process

1 reference

14 February 2019

Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta1-induced apoptosis in rat hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

negative regulation of vascular permeability

1 reference

14 February 2019

Effect of glucocorticoid receptor blockade on pulmonary and renal vascular permeability in scalded rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

glucocorticoid mediated signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

positive regulation of transcription by RNA polymerase II

2 references

14 February 2019

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

14 February 2019

Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA bin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

response to arsenic-containing substance

1 reference

14 February 2019

Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA bin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

Interaction of rat renal glucocorticoid receptor with Hsp90 and Hsp70 upon stress provoked by mercury

response to mercury ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

response to corticosterone

1 reference

14 February 2019

Modeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

Upregulation of hepatic 11β-hydroxysteroid dehydrogenase-1 expression in calcium-deficient rats

response to calcium ion

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

response to electrical stimulus

1 reference

14 February 2019

Changes of glucocorticoid receptor mRNA expression in basolateral amygdale-kindled rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

positive regulation of dendritic spine development

1 reference

14 February 2019

Corticosterone induces rapid spinogenesis via synaptic glucocorticoid receptors and kinase networks in hippocampus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

positive regulation of cell growth involved in cardiac muscle cell development

1 reference

14 February 2019

Dual role for glucocorticoids in cardiomyocyte hypertrophy and apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

cellular response to magnesium ion

1 reference

14 February 2019

Effect of magnesium-free on glucocorticoid receptor expression in primary cultured cortical neurons of fetal rats in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

cellular response to steroid hormone stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

cellular response to glucocorticoid stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

response to dexamethasone

1 reference

14 February 2019

Synthesized glucocorticoid, dexamethasone regulates the expressions of β₂-adrenoceptor and glucocorticoid receptor mRNAs but not proteins in slow-twitch soleus muscle of rats

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

cellular response to dexamethasone stimulus

1 reference

14 February 2019

Mutations at positions 547-553 of rat glucocorticoid receptors reveal that hsp90 binding requires the presence, but not defined composition, of a seven-amino acid sequence at the amino terminus of the ligand binding domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

positive regulation of glucocorticoid receptor signaling pathway

1 reference

14 February 2019

FoxA1 and glucocorticoid receptor crosstalk via histone H4K16 acetylation at a hormone regulated enhancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06536

nuclear hormone receptor-type zinc finger

has part(s)

1 reference

Nuclear hormone receptor, ligand-binding domain

1 reference