(Q28573478)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

1 reference

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

6

Lei Liu

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Sujuan Chen

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Yijiao Xu

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Baoshan Xu

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Min Guo

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Zhen Zhang

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Hongwei Ma

7

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Zi Chen

8

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Yan Luo

9

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Long Chen

11

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

English

0 references

publication date

20 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

number of pages

11

1 reference

Journal of Neurochemistry

inferred from page(s)

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

119

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

1108-1118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

13 February 2020

cites work

1 reference

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Isoforms of p38MAPK gamma and delta contribute to differentiation of human AML cells induced by 1,25-dihydroxyvitamin D₃

19 March 2017

1 reference

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Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

19 March 2017

1 reference

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3,4-dichloropropionanilide (DCPA) inhibits T-cell activation by altering the intracellular calcium concentration following store depletion

19 March 2017

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Vascular endothelial growth factor (VEGF) signaling regulates hippocampal neurons by elevation of intracellular calcium and activation of calcium/calmodulin protein kinase II and mammalian target of rapamycin

19 March 2017

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Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells

19 March 2017

1 reference

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A single amino acid substitution in a proteasome subunit triggers aggregation of ubiquitinated proteins in stressed neuronal cells

19 March 2017

1 reference

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Cadmium induces caspase-independent apoptosis in liver Hep3B cells: role for calcium in signaling oxidative stress-related impairment of mitochondria and relocation of endonuclease G and apoptosis-inducing factor

19 March 2017

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Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

19 March 2017

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

19 March 2017

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Neuronal CA2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function

19 March 2017

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Phosphatidic acid-mediated mitogenic activation of mTOR signaling

19 March 2017

1 reference

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Potentiation and inhibition of Ca(2+) release-activated Ca(2+) channels by 2-aminoethyldiphenyl borate (2-APB) occurs independently of IP(3) receptors

19 March 2017

1 reference

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19 March 2017

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The TOR pathway: a target for cancer therapy

7 April 2017

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

7 April 2017

1 reference

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Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

29 September 2017

1 reference

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Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

29 September 2017

1 reference

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Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II

29 September 2017

1 reference

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Glutamate preconditioning prevents neuronal death induced by combined oxygen-glucose deprivation in cultured cortical neurons

29 September 2017

1 reference

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Cadmium specifically induces MKP-1 expression via the glutathione depletion-mediated p38 MAPK activation in C6 glioma cells

29 September 2017

1 reference

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Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins

29 September 2017

1 reference

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MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

29 September 2017

1 reference

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Involvement of CaM kinase II in gonadotropin-releasing hormone-induced activation of MAP kinase in cultured hypothalamic neurons

29 September 2017

1 reference

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Calcium-mediated activation of PI3K and p53 leads to apoptosis in thyroid carcinoma cells.

29 September 2017

1 reference

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Calcium/calmodulin-dependent kinase activity is required for efficient induction of osteoclast differentiation and bone resorption by receptor activator of nuclear factor kappa B ligand (RANKL).

29 September 2017

1 reference

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29 September 2017

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Cadmium blocks receptor-mediated Jak/STAT signaling in neurons by oxidative stress

29 September 2017

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Cadmium is acutely toxic for murine hepatocytes: effects on intracellular free Ca(2+) homeostasis.

29 September 2017

1 reference

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Acquired tolerance in cadmium-adapted lung epithelial cells: roles of the c-Jun N-terminal kinase signaling pathway and basal level of metallothionein

29 September 2017

1 reference

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Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis

29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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29 September 2017

1 reference

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Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis

29 September 2017

1 reference

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29 September 2017

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29 September 2017

1 reference

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Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes.

29 September 2017

1 reference

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Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis

29 September 2017

1 reference

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Molecular determinants that mediate selective activation of p38 MAP kinase isoforms

29 September 2017

1 reference

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Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family

29 September 2017

1 reference

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Roles of cytoplasmic Ca2+ and intracellular Ca2+ stores in induction and suppression of apoptosis in S49 cells

29 September 2017

1 reference

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Calcium influx and neurodegeneration

29 September 2017

1 reference

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Calcium signaling in neurodegeneration

29 September 2017

1 reference

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Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Extracellular zinc activates p70 S6 kinase through the phosphatidylinositol 3-kinase signaling pathway

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Toxicokinetics and biochemistry of cadmium with special emphasis on the role of metallothionein.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Reversible generation of a Ca2+-independent form of Ca2+(calmodulin)-dependent protein kinase II by an autophosphorylation mechanism.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Hair element content in learning disabled children

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB). 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites

3 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

2-aminoethoxydiphenyl borane activates a novel calcium-permeable cation channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Involvement of phosphorylated Ca2+/calmodulin-dependent protein kinase II and phosphorylated extracellular signal-regulated protein in the mouse formalin pain model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Gradual micronutrient accumulation and depletion in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Cadmium directly induced the opening of membrane permeability pore of mitochondria which possibly involved in cadmium-triggered apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Initiation of caspase-independent death in mouse mesangial cells by Cd2+: involvement of p38 kinase and CaMK-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Apoptosis and necrosis: two distinct events induced by cadmium in cortical neurons in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Parkinsonism after acute cadmium poisoning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Determination of cadmium and zinc in Alzheimer's brain tissue using inductively coupled plasma mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2011.07493.X

Calmodulin-dependent protein kinase II mediates signal transduction in apoptosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3217117

Calcium/calmodulin-dependent kinase II plays an important role in prostate cancer cell survival

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21933187

12 December 2020

inferred from PubMed ID database lookup

CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21933187

12 December 2020

inferred from PubMed ID database lookup

Evidence for a synergistic interaction between cadmium and endotoxin toxicity and for nitric oxide and cadmium displacement of metals in the kidney

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21933187

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1111/J.1471-4159.2011.07493.X

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933187%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

31 January 2017