(Q28575579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanism (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Jing Wei

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Jia Cheng

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Wenhua Liu

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Zhen Yan

7

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Lara J Duffney

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Katharine R Smith

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

language of work or name

English

0 references

publication date

1 October 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

published in

Journal of Neuroscience

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

volume

33

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

issue

40

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

15767-15778

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

26 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3787498/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

17 March 2017

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Contribution of SHANK3 mutations to autism spectrum disorder

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Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

17 March 2017

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Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

17 March 2017

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The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines

17 March 2017

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Actin binding proteins: regulation of cytoskeletal microfilaments

17 March 2017

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The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42

17 March 2017

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ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

17 March 2017

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Rho proteins, mental retardation and the cellular basis of cognition

17 March 2017

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Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin

17 March 2017

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Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome

17 March 2017

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The Shank family of scaffold proteins

17 March 2017

1 reference

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Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

17 March 2017

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Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation

17 March 2017

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PAK3 mutation in nonsyndromic X-linked mental retardation

17 March 2017

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Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

17 March 2017

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Competitive binding of alpha-actinin and calmodulin to the NMDA receptor

17 March 2017

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

17 March 2017

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Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses

17 March 2017

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Biology of the p21-activated kinases

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7 April 2017

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Proteins of the ADF/cofilin family: essential regulators of actin dynamics

7 April 2017

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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

7 April 2017

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7 April 2017

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Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway

7 April 2017

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Regulation of N-methyl-D-aspartic acid (NMDA) receptors by metabotropic glutamate receptor 7

29 September 2017

1 reference

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From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatment

29 September 2017

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A novel NMDA receptor glycine-site partial agonist, GLYX-13, has therapeutic potential for the treatment of autism

29 September 2017

1 reference

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SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism.

29 September 2017

1 reference

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Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders

29 September 2017

1 reference

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Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome

29 September 2017

1 reference

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Phosphatidylinositol (4,5)-bisphosphate regulation of N-methyl-D-aspartate receptor channels in cortical neurons

29 September 2017

1 reference

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Low dose MK-801 reduces social investigation in mice

29 September 2017

1 reference

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Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.

29 September 2017

1 reference

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Cofilin phosphatases and regulation of actin dynamics

29 September 2017

1 reference

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Rho GTPases, dendritic structure, and mental retardation

29 September 2017

1 reference

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Trafficking of NMDA receptors

29 September 2017

1 reference

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Rho family GTPases as key regulators for neuronal network formation.

29 September 2017

1 reference

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Regulation of dendritic spine stability

29 September 2017

1 reference

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Signaling between the actin cytoskeleton and the postsynaptic density of dendritic spines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Actin-based plasticity in dendritic spines

29 September 2017

1 reference

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Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Synapse structure: glutamate receptors connected by the shanks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Structure, development, and plasticity of dendritic spines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Isolation and characterization of a regulated form of actin depolymerizing factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Mechanisms for acute stress-induced enhancement of glutamatergic transmission and working memory

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Altered cortical synaptic morphology and impaired memory consolidation in forebrain- specific dominant-negative PAK transgenic mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Interfering with Ras signaling using membrane-permeable peptides or drugs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Missense mutation in PAK3, R67C, causes X-linked nonspecific mental retardation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase). Evidence that auto-kinase belongs to a member of the p21-activated kinase family

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Autism spectrum disorder and co-occurring developmental, psychiatric, and medical conditions among children in multiple populations of the United States.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Phosphatidylinositol-4,5-bisphosphate regulates NMDA receptor activity through alpha-actinin.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Regulation of NMDA receptors by neuregulin signaling in prefrontal cortex.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Bimodal effects of MK-801 on locomotion and stereotypy in C57BL/6 mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Differential effects of Rho GTPases on axonal and dendritic development in hippocampal neurones

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Regulation of single NMDA receptor channel activity by alpha-actinin and calmodulin in rat hippocampal granule cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

p21-Activated Kinase 2 in Neutrophils Can Be Regulated by Phosphorylation at Multiple Sites and by a Variety of Protein Phosphatases

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Study of a new schizophrenomimetic drug; sernyl.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Altered transcript expression of NMDA receptor-associated postsynaptic proteins in the thalamus of subjects with schizophrenia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Regulation of NMDA receptor activity by F-actin and myosin light chain kinase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Phosphorylation of cofilin by LIM-kinase is necessary for semaphorin 3A-induced growth cone collapse.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Rapid dendritic remodeling in the developing retina: dependence on neurotransmission and reciprocal regulation by Rac and Rho.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Calcium-induced actin depolymerization reduces NMDA channel activity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787498

Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24089484

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reactivation of phosphorylated actin depolymerizing factor and identification of the regulatory site

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24089484

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.1175-13.2013

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24089484%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

2 references