(Q28577227)

31 January 2017

title

Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells (English)

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31 January 2017

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Chu Chang Chua

1

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31 January 2017

Xuwan Liu

2

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31 January 2017

Jinping Gao

3

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31 January 2017

Ronald C. Hamdy

4

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31 January 2017

Balvin H. L. Chua

5

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31 January 2017

publication date

1 June 2006

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American Journal of Physiology Heart and Circulatory Physiology

31 January 2017

published in

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31 January 2017

volume

290

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31 January 2017

issue

6

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31 January 2017

page(s)

H2606–2613

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

31 January 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Control of apoptosis by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Prospective therapeutic applications of p53 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Doxorubicin treatment in vivo activates caspase-12 mediated cardiac apoptosis in both male and female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Role of p53 in cisplatin-induced tubular cell apoptosis: dependence on p53 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

21 January 2018

Caspase-12: an overview

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Glutathione S-transferase overexpression protects against anthracycline-induced H9C2 cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Cleavage of Poly(ADP-ribose) polymerase measured in situ in individual cells: relationship to DNA fragmentation and cell cycle position during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Pifithrin-alpha protects against doxorubicin-induced apoptosis and acute cardiotoxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Anthracycline and anthraquinone anticancer agents: current status and recent developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Regulation of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Caspases: potential targets for regulating cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Free radical formation by antitumor quinones

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

BID regulation by p53 contributes to chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

p53-dependent caspase-2 activation in mitochondrial release of apoptosis-inducing factor and its role in renal tubular epithelial cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Role of p53 family members in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Subcellular effects of adriamycin in the heart: a concise review

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Phosphorylation sites in the amino-terminal region of mouse p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Effects by doxorubicin on the myocardium are mediated by oxygen free radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Nuclear extracellular signal-regulated kinase 2 phosphorylates p53 at Thr55 in response to doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Pifithrin-alpha suppresses p53 and protects cochlear and vestibular hair cells from cisplatin-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.01138.2005

10.1152/AJPHEART.01138.2005

21 January 2018

Identifiers

DOI

1 reference

31 January 2017

1 reference