(Q28578133)

31 January 2017

title

Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia (English)

1 reference

31 January 2017

0 references

1 reference

Guy C. Brown

4

0 references

author name string

Michael Fricker

series ordinal

1

1 reference

31 January 2017

Anna Vilalta

series ordinal

2

1 reference

31 January 2017

Aviva M. Tolkovsky

series ordinal

3

1 reference

31 January 2017

language of work or name

English

0 references

publication date

29 March 2013

1 reference

Journal of Biological Chemistry

31 January 2017

published in

1 reference

31 January 2017

volume

288

1 reference

31 January 2017

issue

13

1 reference

31 January 2017

page(s)

9145–9152

1 reference

Caspase 8 inhibits programmed necrosis by processing CYLD

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Identification of RIP1 kinase as a specific cellular target of necrostatins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Apoptosis: controlled demolition at the cellular level

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Neuronal death induced by nanomolar amyloid β is mediated by primary phagocytosis of neurons by microglia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

The executioners sing a new song: killer caspases activate microglia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Molecular links between autophagy and apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Neurodegeneration in models of Gram-positive bacterial infections of the central nervous system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

A new concept in neurodegeneration: TNFalpha is a silencer of survival signals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

Primary phagocytosis of viable neurons by microglia activated with LPS or Aβ is dependent on calreticulin/LRP phagocytic signalling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610987

MFG-E8 mediates primary phagocytosis of viable neurons during neuroinflammation.

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.427880

Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.427880

Caspase signalling controls microglia activation and neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.427880

Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.427880

The combination of isoflurane and caspase 8 inhibition results in sustained neuroprotection in rats subject to focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.427880

Inhibiting caspase-8 after injury reduces hypoxic-ischemic brain injury in the newborn rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.427880

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.427880

Protective effect of a caspase inhibitor in models for cerebral ischemia in vitro and in vivo

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23386613

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality

1 reference

https://pubmed.ncbi.nlm.nih.gov/23386613