(Q28580519)

English

Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi

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scholarly article

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31 January 2017

Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi (English)

1 reference

31 January 2017

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based on heuristic

inferred from title

author name string

LiZe Gu

1

1 reference

31 January 2017

BaoSheng Huang

2

1 reference

31 January 2017

Wei Shen

3

1 reference

31 January 2017

Li Gao

4

1 reference

31 January 2017

ZhengZheng Ding

5

1 reference

31 January 2017

HuiWen Wu

6

1 reference

31 January 2017

Jun Guo

7

1 reference

31 January 2017

publication date

3 September 2013

1 reference

31 January 2017

Journal of Neuroinflammation

1 reference

31 January 2017

10

1 reference

31 January 2017

109

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31 January 2017

copyright license

Creative Commons Attribution 2.0 Generic

3 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

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April 2022 Public Data File from Crossref

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3844623/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1186/1742-2094-10-109

0 references

PI3K/Akt-independent negative regulation of JNK signaling by MKP-7 after cerebral ischemia in rat hippocampus

1 reference

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17 March 2017

Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-κB activation and cytokine production of glial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

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Innate immunity in the central nervous system

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17 March 2017

Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

17 March 2017

Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

17 March 2017

FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

17 March 2017

Astrocytes, from brain glue to communication elements: the revolution continues

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7 April 2017

Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep

1 reference

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29 September 2017

Diverse functions of ceramide in cancer cell death and proliferation

1 reference

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29 September 2017

Blocking A2B adenosine receptor alleviates pathogenesis of experimental autoimmune encephalomyelitis via inhibition of IL-6 production and Th17 differentiation

1 reference

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29 September 2017

Brain-immune interactions and ischemic stroke: clinical implications

1 reference

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29 September 2017

Inflammatory cytokines in experimental and human stroke.

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29 September 2017

Ceramide function in the brain: when a slight tilt is enough.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Palmitate-induced PTP1B expression is mediated by ceramide-JNK and nuclear factor κB (NF-κB) activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen-glucose deprivation/reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Goodpasture antigen-binding protein/ceramide transporter binds to human serum amyloid P-component and is present in brain amyloid plaques

1 reference

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29 September 2017

Inflammatory demyelinating brain lesions heralding primary CNS lymphoma.

1 reference

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29 September 2017

The roles of neutral sphingomyelinases in neurological pathologies

1 reference

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29 September 2017

Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Pathophysiology of stroke and stroke-induced retinal ischemia: emerging role of stem cells

1 reference

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29 September 2017

Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Pathological roles of MAPK signaling pathways in human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Hyperoxic reperfusion after global cerebral ischemia promotes inflammation and long-term hippocampal neuronal death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Neuron protection as a therapeutic target in acute ischemic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

The p38alpha kinase plays a central role in inflammation

1 reference

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29 September 2017

Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin

1 reference

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29 September 2017

Astrocyte function and role in motor neuron disease: a future therapeutic target?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Sphingomyelinases: their regulation and roles in cardiovascular pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Astrocyte metabolism and signaling during brain ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

The WD repeat protein FAN regulates lysosome size independent from abnormal downregulation/membrane recruitment of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

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1 reference

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29 September 2017

Role for neutral sphingomyelinase-2 in tumor necrosis factor alpha-stimulated expression of vascular cell adhesion molecule-1 (VCAM) and intercellular adhesion molecule-1 (ICAM) in lung epithelial cells: p38 MAPK is an upstream regulator of nSMase2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Inflammation in areas of remote changes following focal brain lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Neuroprotection for ischemic stroke: two decades of success and failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

The rise and fall of NMDA antagonists for ischemic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Ultraviolet B radiation-induced cell death: critical role of ultraviolet dose in inflammation and lupus autoantigen redistribution

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Intracellular signal transduction pathways activated by ceramide and its metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

29 September 2017

Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

3 June 2018

Palmitate-induced inhibition of insulin gene expression in rat islet β-cells involves the ceramide transport protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3844623

3 June 2018

Sphingomyelinase-induced ceramide production stimulate calcium-independent JNK and PP2A activation following cerebral ischemia

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-10-109

21 January 2018

Purification and characterization of a membrane bound neutral pH optimum magnesium-dependent and phosphatidylserine-stimulated sphingomyelinase from rat brain.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-10-109

21 January 2018

Sustained activation of Src-family tyrosine kinases by ischemia: a potential mechanism mediating extracellular signal-regulated kinase cascades in hippocampal dentate gyrus.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-10-109

21 January 2018

Role of MAPK in ceramide-induced cell death in primary cultured astrocytes from mouse embryonic brain.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-10-109

21 January 2018

Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-10-109

21 January 2018

Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-10-109

21 January 2018

Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-10-109

21 January 2018

Endoplasmic reticulum stress-mediated inhibition of NSMase2 elevates plasma membrane cholesterol and attenuates NO production in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24007266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Geniposide reduces inflammatory responses of oxygen-glucose deprived rat microglial cells via inhibition of the TLR4 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/24007266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/24007266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of FADD for tumor necrosis factor-induced activation of acid sphingomyelinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24007266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-10-109

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/1742-2094-10-109

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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