(Q34489852)

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Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease

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Europe PubMed Central

PubMed publication ID

2 August 2017

Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Alzheimer's disease

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Arundhati Jana

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

Kalipada Pahan

2

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Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

1 September 2010

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Europe PubMed Central

PubMed publication ID

2 August 2017

Journal of Neuroscience

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Europe PubMed Central

PubMed publication ID

2 August 2017

30

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Europe PubMed Central

PubMed publication ID

2 August 2017

38

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

12676-12689

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Overexpression of human S100B exacerbates cerebral amyloidosis and gliosis in the Tg2576 mouse model of Alzheimer's disease

1 reference

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6 July 2018

CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?

1 reference

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6 July 2018

The inflammatory response in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

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Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology

1 reference

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6 July 2018

Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis

1 reference

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6 July 2018

MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65.

1 reference

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6 July 2018

NSAIDs for the Chemoprevention of Alzheimer’s Disease

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

https://pubmed.ncbi.nlm.nih.gov/20861373

12 December 2020

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inferred from PubMed ID database lookup

A simplified method for isolating highly purified neurons, oligodendrocytes, astrocytes, and microglia from the same human fetal brain tissue

1 reference

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6 July 2018

Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide

1 reference

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6 July 2018

Up-regulation of microglial CD11b expression by nitric oxide

1 reference

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6 July 2018

Intrathecal chemokine levels in Alzheimer disease and frontotemporal lobar degeneration.

1 reference

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6 July 2018

Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes

1 reference

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6 July 2018

Inflammatory processes and Alzheimer's disease

1 reference

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6 July 2018

Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Cytokines in neuroinflammation and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Antineuroinflammatory effect of NF-kappaB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Role of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Innate immunity in Alzheimer's disease: a model for local inflammatory reactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Cerebral pattern of pro- and anti-inflammatory cytokines in dementias

1 reference

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6 July 2018

Role of Very-late Antigen-4 (VLA-4) in Myelin Basic Protein-primed T Cell Contact-induced Expression of Proinflammatory Cytokines in Microglial Cells

1 reference

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6 July 2018

Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Ceramide in apoptosis: an overview and current perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Beta-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo: involvement of the p38MAPK pathway.

1 reference

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6 July 2018

Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Role of nuclear factor kappaB in synovial inflammation

1 reference

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6 July 2018

Ligation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells

1 reference

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6 July 2018

Induction of nitric-oxide synthase and activation of NF-kappaB by interleukin-12 p40 in microglial cells

1 reference

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6 July 2018

Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Inflammation and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Glial responses to steroids as markers of brain aging

1 reference

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6 July 2018

Molecular basis of the neurodegenerative disorders

1 reference

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6 July 2018

Nitric oxide and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

The role of nuclear factor-kappa B in cytokine gene regulation

1 reference

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6 July 2018

Activation of CPP32 during apoptosis of neurons and astrocytes

1 reference

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6 July 2018

Functions of ceramide in coordinating cellular responses to stress

1 reference

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6 July 2018

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

1 reference

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6 July 2018

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

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6 July 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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6 July 2018

Antiinflammatory drugs in the treatment of Alzheimer's disease.

1 reference

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6 July 2018

Staurosporine induces programmed cell death in embryonic neurons and activation of the ceramide pathway.

1 reference

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6 July 2018

Ceramide induces apoptosis in cultured mesencephalic neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

6 July 2018

Abnormally phosphorylated tau protein related to the formation of neurofibrillary tangles and neuropil threads in the cerebral cortex of sheep and goat

1 reference

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Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

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Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice.

1 reference

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27 October 2018

Amyloid-beta peptide enhances tumor necrosis factor-alpha-induced iNOS through neutral sphingomyelinase/ceramide pathway in oligodendrocytes

1 reference

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27 October 2018

Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

27 October 2018

Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK.

1 reference

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27 October 2018

Expression of nitric oxide system in clinically evaluated cases of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

27 October 2018

Amyloid beta peptide-induced corpus callosum damage and glial activation in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020912

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Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease

1 reference

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27 October 2018

Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.

1 reference

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Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation

1 reference

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Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase

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Role of mitogen-activated protein kinases in inducible nitric oxide synthase and TNFalpha expression in human fetal astrocytes.

1 reference

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27 October 2018

Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease.

1 reference

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27 October 2018

Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

1 reference

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27 October 2018

Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases

1 reference

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27 October 2018

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

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Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

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9 December 2018

Expression of a dominant-negative mutant of p21(ras) inhibits induction of nitric oxide synthase and activation of nuclear factor-kappaB in primary astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20861373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20861373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated glia induce neuron death via MAP kinase signaling pathways involving JNK and p38

1 reference

https://pubmed.ncbi.nlm.nih.gov/20861373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20861373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory processes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20861373

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1243-10.2010

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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