(Q28582005)

31 January 2017

title

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death (English)

1 reference

31 January 2017

0 references

1 reference

Timothy Tree

9

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Marta Vives-Pi

object named as

Marta Vives-Pi

7

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Mark Peakman

object named as

Mark Peakman

15

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Piero Marchetti

object named as

Piero Marchetti

10

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author name string

Sefina Arif

1

1 reference

31 January 2017

Fabrice Moore

2

1 reference

31 January 2017

Katherine Marks

3

1 reference

31 January 2017

Thomas Bouckenooghe

4

1 reference

31 January 2017

Colin M. Dayan

5

1 reference

31 January 2017

Raquel Planas

6

1 reference

31 January 2017

Jake Powrie

8

1 reference

31 January 2017

Guo Cai Huang

11

1 reference

31 January 2017

Esteban N. Gurzov

12

1 reference

31 January 2017

Ricardo Pujol-Borrell

13

1 reference

31 January 2017

Decio L. Eizirik

14

1 reference

31 January 2017

language of work or name

English

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publication date

1 August 2011

1 reference

31 January 2017

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31 January 2017

volume

60

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31 January 2017

issue

8

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31 January 2017

page(s)

2112–2119

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

31 January 2017

copyright license

start time

30 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Genetics, pathogenesis and clinical interventions in type 1 diabetes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Stats: transcriptional control and biological impact

17 March 2017

1 reference

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Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

7 April 2017

1 reference

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T cells that trigger acute experimental autoimmune encephalomyelitis also mediate subsequent disease relapses and predominantly produce IL-17.

7 April 2017

1 reference

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Ustekinumab for the treatment of psoriasis: review of three multicenter clinical trials

29 September 2017

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LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

29 September 2017

1 reference

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Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease.

29 September 2017

1 reference

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Translational mini-review series on Th17 cells: are T helper 17 cells really pathogenic in autoimmunity?

29 September 2017

1 reference

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The aryl hydrocarbon receptor in immunity

29 September 2017

1 reference

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Validity and reproducibility of measurement of islet autoreactivity by T-cell assays in subjects with early type 1 diabetes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

29 September 2017

1 reference

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Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

29 September 2017

1 reference

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Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: new findings at clinical onset and in long-standing diabetes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Cutting Edge: Increased IL-17-Secreting T Cells in Children with New-Onset Type 1 Diabetes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

IL-17 immunity in human type 1 diabetes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3142078

Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes

27 November 2018

1 reference

12 December 2020

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

12 December 2020

A new in vitro model for the study of pancreatic A and B cells

1 reference

12 December 2020

Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR

1 reference

12 December 2020

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

1 reference

12 December 2020

IL17 and IFNgamma production by peripheral blood mononuclear cells from clinically isolated syndrome to secondary progressive multiple sclerosis

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB10-1643

1 reference

release_rcvt2kciivelvefvtsxx3c5vti

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rcvt2kciivelvefvtsxx3c5vti

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

1 reference