(Q28582042)

31 January 2017

title

siRNA against plasminogen activator inhibitor-1 ameliorates bleomycin-induced lung fibrosis in rats (English)

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31 January 2017

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Yan-ping Zhang

1

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31 January 2017

Wen-bin Li

2

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31 January 2017

Wei-li Wang

3

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31 January 2017

Jian Liu

4

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31 January 2017

Shu-xia Song

5

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31 January 2017

Lin-lin Bai

6

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31 January 2017

Yu-yan Hu

7

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31 January 2017

Ya-dong Yuan

8

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31 January 2017

Min Zhang

9

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31 January 2017

publication date

1 July 2012

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Acta Pharmacologica Sinica

31 January 2017

published in

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31 January 2017

volume

33

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31 January 2017

issue

7

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31 January 2017

page(s)

897–908

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The promises and pitfalls of RNA-interference-based therapeutics

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

The myofibroblast: one function, multiple origins

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Structure of human urokinase plasminogen activator in complex with its receptor

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Induction of Apoptosis in Vascular Cells by Plasminogen Activator Inhibitor-1 and High Molecular Weight Kininogen Correlates with Their Anti-Adhesive Properties

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and mice

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Suppression of plasminogen activator inhibitor-1 by RNA interference attenuates pulmonary fibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Inhibition of plasminogen activator inhibitor-1 expression by siRNA in rat hepatic stellate cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Inhalable siRNA: potential as a therapeutic agent in the lungs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

The urokinase-system--role of cell proliferation and apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Urokinase receptor cleavage: a crucial step in fibroblast-to-myofibroblast differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Evolving concepts of apoptosis in idiopathic pulmonary fibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

The plasminogen activation system reduces fibrosis in the lung by a hepatocyte growth factor-dependent mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Reduction in fibrotic tissue formation in mice genetically deficient in plasminogen activator inhibitor-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

ERK(MAPK) activity as a determinant of tumor growth and dormancy; regulation by p38(SAPK).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Regulation of Rac1 activation by the low density lipoprotein receptor-related protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

The myofibroblast in pulmonary fibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Plasminogen activator inhibitor 1 protects fibrosarcoma cells from etoposide-induced apoptosis through activation of the PI3K/Akt cell survival pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

The Myofibroblast Is the Predominant Plasminogen Activator Inhibitor-1-Expressing Cell Type in Human Breast Carcinomas

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Urokinase-type plasminogen activator gene therapy in liver cirrhosis is mediated by collagens gene expression down-regulation and up-regulation of MMPs, HGF and VEGF.

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.39

Adenovirus-mediated transfer of siRNA against PAI-1 mRNA ameliorates hepatic fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.39

Plasminogen activator inhibitor-1 inhibits prostate tumor growth through endothelial apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.39

Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.39

Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.39

Inhibition of extracellular signal-regulated kinase 1 by adenovirus mediated small interfering RNA attenuates hepatic fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2012.39

Historical analysis of PAI-1 from its discovery to its potential role in cell motility and disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Urokinase-induced migration of human vascular smooth muscle cells requires coupling of the small GTPases RhoA and Rac1 to the Tyk2/PI3-K signalling pathway

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4011146

Cell-matrix and cell-cell contacts of myofibroblasts: role in connective tissue remodeling

27 November 2018

1 reference

12 December 2020

Depressed bronchoalveolar urokinase activity in patients with adult respiratory distress syndrome

1 reference

12 December 2020

[Idiopathic pulmonary fibrosis]

1 reference

12 December 2020

A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells

1 reference

12 December 2020

uPAR-uPA-PAI-1 interactions and signaling: a vascular biologist's view

1 reference

12 December 2020

Plasminogen activator inhibitor-1: the double-edged sword in apoptosis

1 reference

12 December 2020

Regulation of programmed cell death by plasminogen activator inhibitor type 1 (PAI-1)

1 reference

12 December 2020

Identifiers

DOI

10.1038/APS.2012.39

1 reference

Dimensions Publication ID

1015458136

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