(Q83162820)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

Plasminogen activator inhibitor-1: the double-edged sword in apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

2

Victoria A Ploplis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Rashna D Balsara

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

1 December 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

Thrombosis and Haemostasis

19 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

1029-1036

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

Plasminogen activator inhibitor-1 aids nerve growth factor-induced differentiation and survival of pheochromocytoma cells by activating both the extracellular signal-regulated kinase and c-Jun pathways

19 January 2020

cites work

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12 December 2020

Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1.

1 reference

12 December 2020

A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells

1 reference

12 December 2020

Plasminogen activator inhibitor-1 impairs plasminogen activation-mediated vascular smooth muscle cell apoptosis

1 reference

12 December 2020

The contributions of integrin affinity and integrin-cytoskeletal engagement in endothelial and smooth muscle cell adhesion to vitronectin.

1 reference

12 December 2020

Breast cancer and metabolic syndrome linked through the plasminogen activator inhibitor-1 cycle

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12 December 2020

Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis

1 reference

12 December 2020

High serum level of plasminogen activator inhibitor-1 predicts histological grade of intracerebral gliomas

1 reference

12 December 2020

Plasminogen activator inhibitor-1 inhibits prostate tumor growth through endothelial apoptosis.

1 reference

12 December 2020

Intraperitoneal infusion of recombinant plasminogen activator inhibitor type 2 induced apoptosis in implanted human colon cancer and inhibited its growth and liver metastasis

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12 December 2020

Metabolic syndrome, haemostasis and thrombosis

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12 December 2020

HtrA1-dependent proteolysis of TGF-beta controls both neuronal maturation and developmental survival.

1 reference

12 December 2020

Plasminogen activator inhibitor 1, the primary regulator of fibrinolysis, in normal human cerebrospinal fluid.

1 reference

12 December 2020

Prevention of metastasis by inhibition of the urokinase receptor

1 reference

12 December 2020

Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy

1 reference

12 December 2020

Urokinase and plasminogen activator inhibitor type 1 in pulmonary adenocarcinoma.

1 reference

12 December 2020

Elevated levels of urokinase-type plasminogen activator and plasminogen activator inhibitor type-1 in malignant human brain tumors

1 reference

12 December 2020

Plasminogen activators and plasminogen activator inhibitor 1 in urinary tract cancer

1 reference

12 December 2020

Increased levels of plasminogen activator inhibitor-1 (PAI-1) in human brain tumors

1 reference

12 December 2020

Inhibition of interleukin-1 beta converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition.

1 reference

12 December 2020

Plasminogen activator inhibitor-1 and prognosis in primary breast cancer

1 reference

12 December 2020

Plasminogen activator inhibitor-1 in the cerebrospinal fluid as an index of neurological disease.

1 reference

12 December 2020

Inactive urokinase and increased levels of its inhibitor type 1 in colorectal cancer liver metastasis

1 reference

12 December 2020

Plasminogen activators and plasminogen activator inhibitors in blood and tumour fluids of patients with ovarian cancer

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12 December 2020

Co-expression of urokinase, urokinase receptor and PAI-1 is necessary for optimum invasiveness of cultured lung cancer cells

1 reference

12 December 2020

Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapy

1 reference

12 December 2020

Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.

1 reference

12 December 2020

Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells

1 reference

12 December 2020

Clinical relevance of the urokinase-type and tissue-type plasminogen activators and of their type 1 inhibitor in breast cancer

1 reference

12 December 2020

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

1 reference

12 December 2020

Structural requirements for the growth factor activity of the amino-terminal domain of urokinase

1 reference

12 December 2020

Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques

1 reference

12 December 2020

Apoptosis in human atherosclerosis and restenosis

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12 December 2020

Evidence for apoptosis in human atherogenesis and in a rat vascular injury model

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12 December 2020

Tissue-type plasminogen activator-induced invasion and metastasis of murine melanomas

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12 December 2020

Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

1 reference

12 December 2020

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

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12 December 2020

Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro

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12 December 2020

The urokinase system of plasminogen activation and prognosis in 2780 breast cancer patients

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12 December 2020

Apoptosis and regulation of Bax and Bcl-X proteins during human neonatal vascular remodeling

1 reference

12 December 2020

Plasminogen activator inhibitor 1 may promote tumour growth through inhibition of apoptosis

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12 December 2020

Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1.

1 reference

12 December 2020

The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies

1 reference

12 December 2020

Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization

1 reference

12 December 2020

Recombinant PAI-1 inhibits angiogenesis and reduces size of LNCaP prostate cancer xenografts in SCID mice

1 reference

12 December 2020

Dedifferentiation of serous ovarian cancer from cystic to solid tumors is associated with increased expression of mRNA for urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1)

1 reference

12 December 2020

Urokinase/urokinase receptor and vitronectin/alpha(v)beta(3) integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways

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12 December 2020

Inhibition of angiogenesis in vivo by plasminogen activator inhibitor-1

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12 December 2020

Plasminogen activator inhibitor-1 promotes angiogenesis by stimulating endothelial cell migration toward fibronectin

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12 December 2020

Deficient release of plasminogen activator inhibitor-1 from astrocytes triggers apoptosis in neuronal cells

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12 December 2020

Attenuation of neointima formation following arterial injury in PAI-1 deficient mice.

1 reference

12 December 2020

Plasminogen activator inhibitor type 1 is increased in the arterial wall of type II diabetic subjects

1 reference

12 December 2020

213Bi-PAI2 conjugate selectively induces apoptosis in PC3 metastatic prostate cancer cell line and shows anti-cancer activity in a xenograft animal model

1 reference

12 December 2020

Myofibroblasts and mechano-regulation of connective tissue remodelling

1 reference

12 December 2020

Endogenous vitronectin and plasminogen activator inhibitor-1 promote neointima formation in murine carotid arteries

1 reference

12 December 2020

Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-beta 1 against NMDA-induced necrosis

1 reference

12 December 2020

Transforming growth factor alpha-induced expression of type 1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity.

1 reference

12 December 2020

Induction of Apoptosis in Vascular Cells by Plasminogen Activator Inhibitor-1 and High Molecular Weight Kininogen Correlates with Their Anti-Adhesive Properties

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12 December 2020

Amyloid β-Protein Stimulates the Expression of Urokinase-type Plasminogen Activator (uPA) and Its Receptor (uPAR) in Human Cerebrovascular Smooth Muscle Cells

1 reference

12 December 2020

Dose-dependent modulation of choroidal neovascularization by plasminogen activator inhibitor type I: implications for clinical trials

1 reference

12 December 2020

Pericellular plasmin induces smooth muscle cell anoikis.

1 reference

12 December 2020

The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration.

1 reference

12 December 2020

Enhanced in vitro proliferation of aortic endothelial cells from plasminogen activator inhibitor-1-deficient mice.

1 reference

12 December 2020

Inhibition of apoptosis and caspase-3 in vascular smooth muscle cells by plasminogen activator inhibitor type-1.

1 reference

12 December 2020

The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.

1 reference

12 December 2020

Host-derived plasminogen activator inhibitor-1 (PAI-1) concentration is critical for in vivo tumoral angiogenesis and growth

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12 December 2020

Proliferation of a human epidermal tumor cell line stimulated by urokinase

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12 December 2020

Increased plasminogen activator inhibitor activity in non insulin dependent diabetic patients--relationship with plasma insulin

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12 December 2020

Time course of smooth muscle cell proliferation in the intima and media of arteries following experimental angioplasty

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12 December 2020

Urokinase-type plasminogen activation in three human breast cancer cell lines correlates with their in vitro invasiveness

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12 December 2020

Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and liver in an athymic mouse model

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12 December 2020

Clinical relevance of urokinase plasminogen activator, its receptor, and its inhibitor in patients with renal cell carcinoma

1 reference

12 December 2020

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

1 reference

12 December 2020

The pro- or antiangiogenic effect of plasminogen activator inhibitor 1 is dose dependent

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12 December 2020

Neuronal cell death and tPA.

1 reference

12 December 2020

Cerebrospinal fluid plasminogen activator inhibitor-1 in patients with neurological disease

1 reference

12 December 2020

Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin

1 reference

12 December 2020

Elevated plasma levels of urokinase plasminogen activator receptor in non-small cell lung cancer patients

1 reference

12 December 2020

uPA, uPAR, PAI-1: key intersection of proteolytic, adhesive and chemotactic highways?

1 reference

12 December 2020

The level of urokinase-type plasminogen activator receptor is increased in serum of ovarian cancer patients

1 reference

12 December 2020

Increased plasminogen activator inhibitor type 1 in coronary artery atherectomy specimens from type 2 diabetic compared with nondiabetic patients: a potential factor predisposing to thrombosis and its persistence

1 reference

12 December 2020

Production of urokinase-type plasminogen activator (u-PA) and plasminogen activator inhibitor-1 (PAI-1) in human brain tumours

1 reference

12 December 2020

Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.

1 reference

12 December 2020

Augmentation of arterial endothelial cell expression of the plasminogen activator inhibitor type-1 (PAI-1) gene by proinsulin and insulin in vivo

1 reference

12 December 2020

Apoptosis and cell proliferation after porcine coronary angioplasty

1 reference

12 December 2020

Tissue plasminogen activator contributes to the late phase of LTP and to synaptic growth in the hippocampal mossy fiber pathway

1 reference

12 December 2020

Prognostic significance of the receptor for urokinase plasminogen activator in breast cancer

1 reference

12 December 2020

Plasminogen activator inhibitor type 1 in cytosolic tumor extracts predicts prognosis in low-risk breast cancer patients

1 reference

12 December 2020

The plasminogen-plasminogen activator (PA) system in neuroblastoma: role of PA inhibitor-1 in metastasis

1 reference

12 December 2020

BDNF stimulates expression, activity and release of tissue-type plasminogen activator in mouse cortical neurons

1 reference

12 December 2020

Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice

1 reference

12 December 2020

Plasma Urokinase Receptor Levels in Patients With Colorectal Cancer: Relationship to Prognosis

1 reference

12 December 2020

Role of smooth muscle cell death in advanced coronary primary lesions: implications for plaque instability

1 reference

12 December 2020

Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9

1 reference

12 December 2020

Malignant transformation of wild-type but not plasminogen activator inhibitor-1 gene-deficient fibroblasts decreases cellular sensitivity to chemotherapy-mediated apoptosis

1 reference

12 December 2020

RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo

1 reference

12 December 2020

Indication of a role of plasminogen activator inhibitor type I in protecting murine fibrosarcoma cells against apoptosis

1 reference

12 December 2020

Plasminogen activation: a mediator of vascular smooth muscle cell apoptosis in atherosclerotic plaques

1 reference

12 December 2020

siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells.

1 reference

12 December 2020

Plasminogen inhibits TNFalpha-induced apoptosis in monocytes

1 reference

12 December 2020

Urokinase signaling through its receptor protects against anoikis by increasing BCL-xL expression levels

1 reference

12 December 2020

Identifiers

DOI

10.1160/TH08-07-0427

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19132226%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

19132226

1 reference