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The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent
scientific journal article
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scholarly article
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PubMed
PubMed ID
9488468
retrieved
31 January 2017
title
The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent
(English)
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PubMed
PubMed ID
9488468
retrieved
31 January 2017
main subject
molecular chaperones
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author name string
L. Whitesell
series ordinal
1
1 reference
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PubMed
PubMed ID
9488468
retrieved
31 January 2017
P. D. Sutphin
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
9488468
retrieved
31 January 2017
E. J. Pulcini
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
9488468
retrieved
31 January 2017
J. D. Martinez
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
9488468
retrieved
31 January 2017
P. H. Cook
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5
1 reference
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PubMed
PubMed ID
9488468
retrieved
31 January 2017
language of work or name
English
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publication date
1 March 1998
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PubMed
PubMed ID
9488468
retrieved
31 January 2017
published in
Molecular and Cellular Biology
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stated in
PubMed
PubMed ID
9488468
retrieved
31 January 2017
volume
18
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stated in
PubMed
PubMed ID
9488468
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31 January 2017
page(s)
1517–1524
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stated in
PubMed
PubMed ID
9488468
retrieved
31 January 2017
issue
3
1 reference
stated in
PubMed
PubMed ID
9488468
retrieved
31 January 2017
cites work
The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
A pathway of multi-chaperone interactions common to diverse regulatory proteins: estrogen receptor, Fes tyrosine kinase, heat shock transcription factor Hsf1, and the aryl hydrocarbon receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
Regulation of p53 stability by Mdm2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
Multiple p53 protein isoforms and formation of oligomeric complexes with heat shock proteins Hsp70 and Hsp90 in the human mammary tumor, T47D, cell line
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
17 March 2017
mdm2 expression is induced by wild type p53 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
7 April 2017
Cell cycle control and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
7 April 2017
Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Activation of the cryptic DNA binding function of mutant forms of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Microinjection of monoclonal antibody PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
29 September 2017
Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Induction of WAF1/CIP1 by a p53-independent pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Geldanamycin selectively destabilizes and conformationally alters mutated p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Interaction of heat-shock protein 70 with p53 translated in vitro: evidence for interaction with dimeric p53 and for a role in the regulation of p53 conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
3 June 2018
Reconstitution of the steroid receptor.hsp90 heterocomplex assembly system of rabbit reticulocyte lysate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
27 November 2018
Post-translational modification of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108866
retrieved
27 November 2018
Different tumor-derived p53 mutants exhibit distinct biological activities
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Binding of p23 and hsp90 during assembly with the progesterone receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
In vivo ubiquitination and proteasome-mediated degradation of p53(1)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Interactions of p60, a mediator of progesterone receptor assembly, with heat shock proteins hsp90 and hsp70
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular chaperone machines: chaperone activities of the cyclophilin Cyp-40 and the steroid aporeceptor-associated protein p23
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The p53 activation and apoptosis induced by DNA damage are reversibly inhibited by salicylate
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulation of DNA binding and transactivation in p53 by nuclear localization and phosphorylation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9488468
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.18.3.1517
0 references
PMCID
108866
0 references
PubMed ID
9488468
1 reference
stated in
PubMed
PubMed ID
9488468
retrieved
31 January 2017
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