(Q28584911)

31 January 2017

title

Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis (English)

1 reference

Protein tyrosine phosphatase, receptor type, D

31 January 2017

main subject

1 reference

Signal transducer and activator of transcription 3

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

5

Cameron W Brennan

Cameron W

Brennan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

6

Nikolaus Schultz

Nikolaus

Schultz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

7

Kenneth L Pitter

Kenneth L

Pitter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

10

Eric C

Holland

Eric C Holland

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Berenice Ortiz

1

Berenice

Ortiz

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Alicia Pedraza

4

Alicia

Pedraza

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Armida W M Fabius

2

Armida W M

Fabius

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Wei H Wu

3

Wei H

Wu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Jacqueline F Bromberg

8

Jacqueline F

Bromberg

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Jason T Huse

9

Jason T

Huse

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Timothy A Chan

11

Timothy A

Chan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

3 June 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 January 2017

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

111

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

22

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

8149-8154

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

Targeting the tumor microenvironment: JAK-STAT3 signaling

4 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Comprehensive molecular portraits of human breast tumours

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

An integrated genomic analysis of human glioblastoma multiforme

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Somatic cell type specific gene transfer reveals a tumor-promoting function for p21(Waf1/Cip1)

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

The 2007 WHO classification of tumours of the central nervous system

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

The INK4a/ARF network in tumour suppression

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

The landscape of somatic copy-number alteration across human cancers

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Protective and pathogenic functions of macrophage subsets

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

"Activated" STAT proteins: a paradoxical consequence of inhibited JAK-STAT signaling in cytomegalovirus-infected cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Breakpoint features of genomic rearrangements in neuroblastoma with unbalanced translocations and chromothripsis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Microglia and macrophages in malignant gliomas: recent discoveries and implications for promising therapies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Reduced microglial CX3CR1 expression delays neurofibromatosis-1 glioma formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Macrophages in tumor microenvironments and the progression of tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

The molecular profile of microglia under the influence of glioma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Neurofibromatosis-1 heterozygosity increases microglia in a spatially and temporally restricted pattern relevant to mouse optic glioma formation and growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

The transcriptional network for mesenchymal transformation of brain tumours.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Mutational inactivation of PTPRD in glioblastoma multiforme and malignant melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Protein-tyrosine phosphatases and cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

An RCAS-TVA-based approach to designer mouse models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Modeling gliomagenesis with somatic cell gene transfer using retroviral vectors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Modeling Adult Gliomas Using RCAS/t-va Technology

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4050622

Polymorphism in protein tyrosine phosphatase receptor delta is associated with the risk of clear cell renal cell carcinoma.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1401952111

The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1401952111

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24843164

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1401952111

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

ADS bibcode

2014PNAS..111.8149O

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24843164%20AND%20SRC:MED&resulttype=core&format=json