(Q28587095)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

2 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

C H O'Flanagan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

V A Morais

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

W Wurst

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

B De Strooper

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

31 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

34

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

11

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

1363-1374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

12 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Phylogenetic and in silico structural analysis of the Parkinson disease-related kinase PINK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1 protein in normal human brain and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Parallel high-throughput RNA interference screens identify PINK1 as a potential therapeutic target for the treatment of DNA mismatch repair-deficient cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PINK1- and Parkin-mediated mitophagy at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Involvement and interplay of Parkin, PINK1, and DJ1 in neurodegenerative and neuroinflammatory disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Parkin as a tumor suppressor gene for hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The quest for the 1p36 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The c-Rel transcription factor can both induce and inhibit apoptosis in the same cells via the upregulation of MnSOD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial fission in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial fission, fusion, and stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial DNA mutations in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial dynamics and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The PINK1/Parkin pathway regulates mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

RALA and RALBP1 regulate mitochondrial fission at mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Morphological adjustment of senescent cells by modulating caveolin-1 status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Coupling mitochondrial and cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Increased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Cyclin D1: polymorphism, aberrant splicing and cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The spindle checkpoint, aneuploidy, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Aneuploidy stokes the fire

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Review: cell cycle aberrations and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

The involvement of cell cycle events in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Tumorigenesis and neurodegeneration: two sides of the same coin?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.81

Mitochondrial remodeling in cancer metabolism and survival: potential for new therapies

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24681957

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.81

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 March 2020

1000604531

0 references

Fatcat ID

release_wuredwlnsjdlljzmsf3ou5r63y

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wuredwlnsjdlljzmsf3ou5r63y

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24681957%20AND%20SRC:MED&resulttype=core&format=json