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Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
title
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression
(English)
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
main subject
Gremlin 1, DAN family BMP antagonist
1 reference
stated in
GOA release 2020-03-11
author
Denis Duboule
series ordinal
11
0 references
François Spitz
series ordinal
3
object named as
François Spitz
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
Odyssé Michos
object named as
Odyssé Michos
series ordinal
2
0 references
Aimée Zuniga
object named as
Aimée Zuniga
series ordinal
1
0 references
Rolf Zeller
object named as
Rolf Zeller
series ordinal
13
0 references
Kristina Vintersten
series ordinal
7
object named as
Kristina Vintersten
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
author name string
Anna-Pavlina G. Haramis
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
Lia Panman
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
Antonella Galli
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
Christian Klasen
series ordinal
8
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
William Mansfield
series ordinal
9
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
Sylwia Kuc
series ordinal
10
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
Rosanna Dono
series ordinal
12
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
publication date
1 July 2004
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
published in
Genes & Development
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
volume
18
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
page(s)
1553–1564
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stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
issue
13
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
cites work
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis
1 reference
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PubMed Central
reference URL
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Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables
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17 March 2017
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
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PubMed Central
reference URL
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17 March 2017
A locus for asphyxiating thoracic dystrophy, ATD, maps to chromosome 15q13
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PubMed Central
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17 March 2017
Formins: signaling effectors for assembly and polarization of actin filaments
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17 March 2017
A global control region defines a chromosomal regulatory landscape containing the HoxD cluster
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17 March 2017
Initial sequencing and comparative analysis of the mouse genome
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17 March 2017
Functions of FGF signalling from the apical ectodermal ridge in limb development
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17 March 2017
Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly
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PubMed Central
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17 March 2017
The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb
1 reference
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PubMed Central
reference URL
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17 March 2017
The role of a single formin isoform in the limb and renal phenotypes of limb deformity
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PubMed Central
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17 March 2017
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors
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Synpolydactyly in mice with a targeted deficiency in the HoxD complex
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17 March 2017
Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation
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PubMed Central
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17 March 2017
An inherited limb deformity created by insertional mutagenesis in a transgenic mouse
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17 March 2017
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells
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7 April 2017
VISTA : visualizing global DNA sequence alignments of arbitrary length
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7 April 2017
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
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7 April 2017
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7 April 2017
Comparative Genomic Analysis of the Eight-Membered Ring Cystine Knot-Containing Bone Morphogenetic Protein Antagonists
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PubMed Central
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29 September 2017
Patterning the limb before and after SHH signalling
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PubMed Central
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29 September 2017
Limb anomalies: Developmental and evolutionary aspects
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PubMed Central
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29 September 2017
Functional genomics in the mouse
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PubMed Central
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29 September 2017
Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations
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29 September 2017
Capitalizing on large-scale mouse mutagenesis screens
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PubMed Central
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29 September 2017
Synexpression groups in eukaryotes
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PubMed Central
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29 September 2017
Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.
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PubMed Central
reference URL
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29 September 2017
Formin defines a large family of morphoregulatory genes and functions in establishment of the polarising region
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PubMed Central
reference URL
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29 September 2017
The mouse formin (Fmn) gene: abundant circular RNA transcripts and gene-targeted deletion analysis.
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29 September 2017
Sequence and expression of a novel mouse gene PRDC (protein related to DAN and cerberus) identified by a gene trap approach
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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29 September 2017
Reverse genetics by chemical mutagenesis in Caenorhabditis elegans
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PubMed Central
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29 September 2017
Transposon tools for recombinant DNA manipulation: characterization of transcriptional regulators from yeast, Xenopus, and mouse.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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29 September 2017
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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29 September 2017
Disruption of formin-encoding transcripts in two mutant limb deformity alleles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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29 September 2017
Molecular and genetic characterization of a radiation-induced structural rearrangement in mouse chromosome 2 causing mutations at the limb deformity and agouti loci
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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29 September 2017
A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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29 September 2017
Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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3 June 2018
The same genomic region is disrupted in two transgene-induced limb deformity alleles
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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3 June 2018
Developmental biology: first come, first served.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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27 November 2018
Cenani-Lenz syndrome with renal hypoplasia is not linked to FORMIN or GREMLIN.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
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27 November 2018
Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
retrieved
27 November 2018
The mouse formin (Fmn) gene: genomic structure, novel exons, and genetic mapping.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
retrieved
27 November 2018
The limb deformity mutation disrupts the SHH/FGF-4 feedback loop and regulation of 5' HoxD genes during limb pattern formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
retrieved
27 November 2018
A conserved enhancer of the human and murine Hoxa-7 gene specifies the anterior boundary of expression during embryonal development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443518
retrieved
27 November 2018
Identifiers
DOI
10.1101/GAD.299904
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
PMCID
443518
0 references
PubMed ID
15198975
1 reference
stated in
PubMed
PubMed ID
15198975
retrieved
31 January 2017
ResearchGate publication ID
8508605
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