(Q28590393)

English

A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation

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scholarly article

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PubMed publication ID

31 January 2017

A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation (English)

1 reference

PubMed publication ID

31 January 2017

SEC63-like (S. cerevisiae)

1 reference

GOA release 2020-03-11

Polycystin 2, transient receptor potential cation channel

1 reference

GOA release 2020-03-11

Protein kinase C substrate 80K-H

1 reference

GOA release 2020-03-11

Polycystin 1, transient receptor potential channel interacting

1 reference

GOA release 2020-03-11

0 references

author name string

Sorin V. Fedeles

1

1 reference

PubMed publication ID

31 January 2017

Xin Tian

2

1 reference

PubMed publication ID

31 January 2017

Anna-Rachel Gallagher

3

1 reference

PubMed publication ID

31 January 2017

Michihiro Mitobe

4

1 reference

PubMed publication ID

31 January 2017

Saori Nishio

5

1 reference

PubMed publication ID

31 January 2017

Seung Hun Lee

6

1 reference

PubMed publication ID

31 January 2017

Yiqiang Cai

7

1 reference

PubMed publication ID

31 January 2017

Lin Geng

8

1 reference

PubMed publication ID

31 January 2017

Craig M. Crews

9

1 reference

PubMed publication ID

31 January 2017

Stefan Somlo

10

1 reference

PubMed publication ID

31 January 2017

language of work or name

0 references

publication date

19 June 2011

1 reference

PubMed publication ID

31 January 2017

Nature Genetics

1 reference

PubMed publication ID

31 January 2017

43

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PubMed publication ID

31 January 2017

7

1 reference

PubMed publication ID

31 January 2017

639–647

1 reference

PubMed publication ID

31 January 2017

PRKCSH/80K-H, the protein mutated in polycystic liver disease, protects polycystin-2/TRPP2 against HERP-mediated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Structural and molecular basis of the assembly of the TRPP2/PKD1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

One step at a time: endoplasmic reticulum-associated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Mutations in SEC63 cause autosomal dominant polycystic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Mutations in PRKCSH cause isolated autosomal dominant polycystic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Bilineal disease and trans-heterozygotes in autosomal dominant polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Identification of a locus for autosomal dominant polycystic liver disease, on chromosome 19p13.2-13.1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

17 March 2017

Roles of N-linked glycans in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

7 April 2017

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

7 April 2017

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

7 April 2017

Polycystic kidney disease, cilia, and planar polarity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Loss of oriented cell division does not initiate cyst formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Glucosidase II beta subunit modulates N-glycan trimming in fission yeasts and mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Ciliary dysfunction in developmental abnormalities and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Polyductin undergoes notch-like processing and regulated release from primary cilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

The transmembrane protein meckelin (MKS3) is mutated in Meckel-Gruber syndrome and the wpk rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Identification and characterization of polycystin-2, the PKD2 gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Interaction of BiP with the J-domain of the Sec63p component of the endoplasmic reticulum protein translocation complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

29 September 2017

Clinical profile of autosomal dominant polycystic liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

3 June 2018

A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

3 June 2018

Somatic mutation in individual liver cysts supports a two-hit model of cystogenesis in autosomal dominant polycystic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

20 June 2018

Patients with isolated polycystic liver disease referred to liver centres: clinical characterization of 137 cases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation in polycystic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3547075

27 November 2018

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/21685914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21685914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lowering of Pkd1 expression is sufficient to cause polycystic kidney disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21685914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quaternary and domain structure of glycoprotein processing glucosidase II

1 reference

https://pubmed.ncbi.nlm.nih.gov/21685914

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of hypolipidemic and antiplatelet treatment in the diabetic patient with renal disease

1 reference

https://api.crossref.org/works/10.1038%2FNG.860

7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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