(Q28591078)

31 January 2017

title

Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human (English)

1 reference

Free fatty acid receptor 4

31 January 2017

0 references

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GOA release 2020-03-11

author

Anneli Pouta

23

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Marjo-Riitta Järvelin

24

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Johannes Hebebrand

36

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Anke Hinney

37

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Philippe Froguel

44

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François Pattou

39

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Beverley Balkau

32

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Loic Yengo

6

Loïc Yengo

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Konstantinos Rouskas

Konstantinos Rouskas

34

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Odile Poulain-Godefroy

Odile Poulain-Godefroy

3

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Atsuhiko Ichimura

Atsuhiko Ichimura

1

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Isabelle Wolowczuk

Isabelle Wolowczuk

42

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Hélène Choquet

Hélène Choquet

11

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Taka-aki Koshimizu

Taka-aki Koshimizu

41

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Amélie Bonnefond

Amélie Bonnefond

4

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Raffaella Buzzetti

Raffaella Buzzetti

21

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Antje Körner

Antje Körner

25

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Wim Van Hul

Wim Van Hul

29

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Paul Elliott

Paul Elliott

22

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Wieland Kiess

26

Wieland Kiess

1 reference

31 January 2017

30

Luc Van Gaal

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31 January 2017

40

David Meyre

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31 January 2017

31

Fritz Horber

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31 January 2017

38

Andre Scherag

1 reference

31 January 2017

18

Maithé Tauber

1 reference

31 January 2017

Akira Hirasawa

2

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31 January 2017

Takafumi Hara

5

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31 January 2017

Ikuo Kimura

7

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31 January 2017

Audrey Leloire

8

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31 January 2017

Ning Liu

9

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31 January 2017

Keiko Iida

10

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31 January 2017

Philippe Besnard

12

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31 January 2017

Cécile Lecoeur

13

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31 January 2017

Sidonie Vivequin

14

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31 January 2017

Kumiko Ayukawa

15

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31 January 2017

Masato Takeuchi

16

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31 January 2017

Kentaro Ozawa

17

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31 January 2017

Claudio Maffeis

19

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31 January 2017

Anita Morandi

20

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31 January 2017

Marie Pigeyre

27

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31 January 2017

Roberto Caiazzo

28

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31 January 2017

Claire Lévy-Marchal

33

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31 January 2017

Anastasia Kouvatsi

35

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31 January 2017

Gozoh Tsujimoto

43

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31 January 2017

language of work or name

English

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publication date

19 February 2012

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31 January 2017

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31 January 2017

volume

483

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31 January 2017

issue

7389

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31 January 2017

page(s)

350–354

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Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

31 January 2017

cites work

1 reference

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Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance

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Structure-activity relationships of GPR120 agonists based on a docking simulation.

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Free fatty acid receptors FFAR1 and GPR120 as novel therapeutic targets for metabolic disorders.

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Adult height distribution in subjects born small for gestational age.

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Biological complexity is under the 'strange attraction' of non-esterified fatty acids

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Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84

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12 December 2020

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

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12 December 2020

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

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12 December 2020

Pleiotropic effects of fatty acids on pancreatic beta-cells

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Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

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12 December 2020

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R125W coding variant in TBC1D1 confers risk for familial obesity and contributes to linkage on chromosome 4p14 in the French population

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12 December 2020

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Combined therapy of dietary fish oil and stearoyl-CoA desaturase 1 inhibition prevents the metabolic syndrome and atherosclerosis

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Successful multi-intervention treatment of severe obesity: a 7-year prospective study with 96% follow-up

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The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population

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MicroRNA-34a inhibits cell proliferation by repressing mitogen-activated protein kinase kinase 1 during megakaryocytic differentiation of K562 cells

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12 December 2020

Variants in the FTO gene are associated with common obesity in the Belgian population

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12 December 2020

Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis

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12 December 2020

Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism

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12 December 2020

Association between BBS6/MKKS gene polymorphisms, obesity and metabolic syndrome in the Greek population

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12 December 2020

The regulation of adipogenesis through GPR120.

1 reference

12 December 2020

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse

1 reference

12 December 2020

Free fatty acids induce cholecystokinin secretion through GPR120.

1 reference

12 December 2020

Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis

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12 December 2020

Prediction of deleterious human alleles

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12 December 2020

Fatty acid desaturation index correlates with body mass and adiposity indices of obesity in Wistar NIN obese mutant rat strains WNIN/Ob and WNIN/GR-Ob

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12 December 2020

Distribution and regulation of protein expression of the free fatty acid receptor GPR120.

1 reference

12 December 2020

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

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12 December 2020

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

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12 December 2020

PANTHER: a library of protein families and subfamilies indexed by function

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12 December 2020

Novel selective ligands for free fatty acid receptors GPR120 and GPR40.

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12 December 2020

Inflammation is associated with a decrease of lipogenic factors in omental fat in women

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12 December 2020

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

12 December 2020

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

1 reference

12 December 2020

An autocrine lactate loop mediates insulin-dependent inhibition of lipolysis through GPR81.

1 reference

12 December 2020

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

1 reference

12 December 2020