(Q28592705)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

cytochrome P450, family 1, subfamily a, polypeptide 1

20 December 2019

main subject

1 reference

GOA release 2020-03-11

author

Jeff Idle

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

David J. Waxman

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

author name string

Xiaochao Ma

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Chong-Sheng Chen

6

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Michael A Malfatti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Kristopher W Krausz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Daniel W Nebert

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

James S Felton

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Frank J Gonzalez

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

language of work or name

English

0 references

publication date

19 October 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

28

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

732-737

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

3

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts

20 December 2019

cites work

2 references

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17 March 2017

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Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes

6 April 2017

1 reference

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Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism

17 March 2017

1 reference

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17 March 2017

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Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung

29 September 2017

1 reference

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The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis

29 September 2017

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DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

29 September 2017

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Lung cancer in nonsmoking Chinese women: a case-control study

29 September 2017

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Repair of DNA lesions induced by ultraviolet irradiation and aromatic amines in normal and repair-deficient human lymphoblastoid cell lines

29 September 2017

1 reference

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Passive smoking: the medical and economic issues

29 September 2017

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Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery

29 September 2017

1 reference

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Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.

3 June 2018

1 reference

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Women and lung cancer: waiting to exhale

3 June 2018

1 reference

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Human hepatic CYP1A1 and CYP1A2 content, determined with specific anti-peptide antibodies, correlates with the mutagenic activation of PhIP.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Enzymatic activities of human lung tissue: relationship with smoking habits

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): formation of 2-hydroxamino-PhIP, a directly acting genotoxic metabolite

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Differential enzyme induction of mouse liver and lung following a single low or high dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Detection of a carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in cigarette smoke condensate.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Fate and distribution of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in mice at a human dietary equivalent dose

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Inhibitory effects of beer on mutation in the Ames test and DNA adduct formation in mouse organs induced by 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Sexually dimorphic P450 gene expression in liver-specific hepatocyte nuclear factor 4alpha-deficient mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Excretion of the N(2)-glucuronide conjugate of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in urine and its relationship to CYP1A2 and NAT2 activity levels in humans

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Lung cancer and indoor air pollution arising from Chinese-style cooking among nonsmoking women living in Shanghai, China

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Localization of CYP1A1 mRNA in human lung by in situ hybridization: comparison with immunohistochemical findings.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Airborne mutagens produced by frying beef, pork and a soy-based food.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1829392

Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human

27 November 2018

1 reference

12 December 2020

CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans

1 reference

12 December 2020

Detection of a carcinogen, 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine, in airborne particles and diesel-exhaust particles

1 reference

12 December 2020

Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450

1 reference

12 December 2020

Epidemiology and prevention of lung cancer in nonsmokers

1 reference

12 December 2020

Lung cancer among Chinese women

1 reference

12 December 2020

Inhibitory monoclonal antibodies to human cytochrome P450 1A2: analysis of phenacetin O-deethylation in human liver

1 reference

12 December 2020

Expression of cytochromes P450 1A1 and 1B1 in human lung from smokers, non-smokers, and ex-smokers

1 reference

12 December 2020

Cooking oil fumes and risk of lung cancer in women in rural Gansu, China

1 reference

12 December 2020

Chinese food cooking and lung cancer in women nonsmokers

1 reference

12 December 2020

DNA adduct levels of 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) in tissues of cynomolgus monkeys after single or multiple dosing

1 reference

12 December 2020

Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by human cytochrome P4501B1

1 reference

12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGL184

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17052995%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

2 references

31 January 2017