(Q34232382)

31 July 2017

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title

The use of gene knockout mice to unravel the mechanisms of toxicity and chemical carcinogenesis (English)

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31 July 2017

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F J Gonzalez

1

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31 July 2017

publication date

1 March 2001

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31 July 2017

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31 July 2017

volume

120

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31 July 2017

issue

1-3

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31 July 2017

page(s)

199-208

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Kinetics of cytochrome P450 2E1-catalyzed oxidation of ethanol to acetic acid via acetaldehyde.

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Acetaminophen hepatoxicity

1 reference

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7 January 2021

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Molecular basis of polymorphic drug metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

1 reference

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7 January 2021

Pharmacogenetic phenotyping and genotyping. Present status and future potential.

1 reference

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7 January 2021

Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases

1 reference

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7 January 2021

Genetic polymorphism of CYP2A6 in relation to cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Role of CYP2E1 in the hepatotoxicity of acetaminophen

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Genetic instabilities in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Ethanol metabolism, cirrhosis and alcoholism

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Potentiation of occupational carbon tetrachloride toxicity by ethanol abuse

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

CYP2A6 gene deletion reduces susceptibility to lung cancer

1 reference

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7 January 2021

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Ethanol induction of acetaminophen toxicity and metabolism

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https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2

1 reference

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7 January 2021

Purification and immunological characterization of a novel cytochrome P450 from C3H/10T1/2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Characterization of a novel cytochrome P450 from the transformable cell line, C3H/10T1/2

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Disruption of the DT diaphorase (NQO1) gene in mice leads to increased menadione toxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Recent advances in molecular genetics of glaucomas

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Cancer risk and low-penetrance susceptibility genes in gene-environment interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Overview of carcinogenic heterocyclic amines

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2801%2900296-X

7 January 2021

10.1016/S0378-4274(01)00296-X

Identifiers

DOI

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31 July 2017

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