(Q28612038)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

review article

1 reference

title

Proteolysis and antigen presentation by MHC class II molecules (English)

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

Cécile Lagaudriere-Gesbert

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

5

Hidde L Ploegh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

Paula Wolf Bryant

1

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Ana-Maria Lennon-Duménil

2

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Edda Fiebiger

3

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

publication date

1 January 2002

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

published in

Advances in Immunology

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

80

2 references

3 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

71-114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

Nonclassical MHC class II molecules

10 November 2019

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HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

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7 January 2021

H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection

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7 January 2021

The use of benzyloxycarbonyl[125I]iodotyrosylalanyldiazomethane as a probe for active cysteine proteinases in human tissues

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7 January 2021

The identification of active forms of cysteine proteinases in Kirsten-virus-transformed mouse fibroblasts by use of a specific radiolabelled inhibitor

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7 January 2021

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7 January 2021

The lysosomal cysteine proteases

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7 January 2021

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Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

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7 January 2021

Both cathepsin B and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class II MHC invariant chain

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7 January 2021

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7 January 2021

12 December 2020

The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation

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7 January 2021

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7 January 2021

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7 January 2021

Full-length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen

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7 January 2021

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Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice

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The role of lysosomal proteinases in MHC class II-mediated antigen processing and presentation

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The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

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7 January 2021

Dominant-interfering Hsc70 mutants disrupt multiple stages of the clathrin-coated vesicle cycle in vivo

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7 January 2021

Two-step mechanism of inhibition of cathepsin B by cystatin C due to displacement of the proteinase occluding loop

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7 January 2021

Sorting signals in the MHC class II invariant chain cytoplasmic tail and transmembrane region determine trafficking to an endocytic processing compartment

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7 January 2021

Purification of the complex of cathepsin L and the MHC class II-associated invariant chain fragment from human kidney

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7 January 2021

Presentation of antigens derived from microorganisms residing in host-cell vacuoles

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7 January 2021

Four Ia invariant chain forms derive from a single gene by alternate splicing and alternate initiation of transcription/translation

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7 January 2021

Vinyl sulfones as mechanism-based cysteine protease inhibitors

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7 January 2021

Cystatin inhibition of cathepsin B requires dislocation of the proteinase occluding loop. Demonstration By release of loop anchoring through mutation of his110.

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7 January 2021

Antigen presentation enhanced by the alternatively spliced invariant chain gene product p41.

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7 January 2021

Gamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action

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7 January 2021

Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells.

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7 January 2021

Peptide loading onto recycling HLA-DR molecules occurs in early endosomes

1 reference

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7 January 2021

Comparative behaviour of calpain and cathepsin B toward peptidyl acyloxymethyl ketones, sulphonium methyl ketones and other potential inhibitors of cysteine proteinases

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7 January 2021

Crystal structure of the wild-type human procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen

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7 January 2021

The Two Mannose 6-Phosphate Receptors Transport Distinct Complements of Lysosomal Proteins

1 reference

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7 January 2021

Characterization by spectroscopic, kinetic and equilibrium methods of the interaction between recombinant human cystatin A (stefin A) and cysteine proteinases

1 reference

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7 January 2021

Functional early endosomes are required for maturation of major histocompatibility complex class II molecules in human B lymphoblastoid cells.

1 reference

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7 January 2021

The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules

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7 January 2021

Regulation of elastinolytic cysteine proteinase activity in normal and cathepsin K-deficient human macrophages

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7 January 2021

Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain

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7 January 2021

The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Synthesis and processing of cathepsin L, an elastase, by human alveolar macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Cathepsins and compartmentalization in antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Destructive proteolysis by cysteine proteases in antigen presentation of ovalbumin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

A role for peptide in determining MHC class II structure

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

An enzyme that removes clathrin coats: purification of an uncoating ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Regulation of cathepsin E expression during human B cell differentiation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Peptidyl diazomethanes as inhibitors of cysteine and serine proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Cathepsin S required for normal MHC class II peptide loading and germinal center development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

The control and facilitation of MHC class II antigen processing by the BCR.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Inhibition of cruzipain, the major cysteine proteinase of the protozoan parasite, Trypanosoma cruzi, by proteinase inhibitors of the cystatin superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Two forms of the Ia antigen-associated invariant chain result from alternative initiations at two in-phase AUGs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Major histocompatibility class II peptide occupancy, antigen presentation, and CD4+ T cell function in mice lacking the p41 isoform of invariant chain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

The proregion of cathepsin L is required for proper folding, stability, and ER exit

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Perturbation of vesicular traffic with the carboxylic ionophore monensin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

The cell biology of antigen presentation in dendritic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Chloroquine and ammonium chloride prevent terminal glycosylation of immunoglobulins in plasma cells without affecting secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Inhibition mechanism of cathepsin L-specific inhibitors based on the crystal structure of papain-CLIK148 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Human cathepsin B is a metastable enzyme stabilized by specific ionic interactions associated with the active site

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

High-affinity binding of two molecules of cysteine proteinases to low-molecular-weight kininogen.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

High-molecular-weight kininogen binds two molecules of cysteine proteinases with different rate constants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Lysosomal cysteine proteases: more than scavengers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Revised definition of substrate binding sites of papain-like cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

The p41 fragment story

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Crystal structures of human procathepsin B at 3.2 and 3.3 Angstroms resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

The cystatins: Protein inhibitors of cysteine proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Get into the groove! Targeting antigens to MHC class II.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Cathepsin D, but not cathepsin B, releases T cell stimulatory fragments from lysozyme that are functional in the context of multiple murine class II MHC molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Processing of the papain precursor. The ionization state of a conserved amino acid motif within the Pro region participates in the regulation of intramolecular processing.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Proteases involved in MHC class II antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Proteolysis in MHC class II antigen presentation: who's in charge?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

MHC Class II Expression Is Regulated in Dendritic Cells Independently of Invariant Chain Degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Interferon gamma induction of pulmonary emphysema in the adult murine lung

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Capture and processing of exogenous antigens for presentation on MHC molecules.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Antigen processing in the endocytic compartment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Human cathepsins W and F form a new subgroup of cathepsins that is evolutionary separated from the cathepsin B- and L-like cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Inhibition of the acidification of endosomes and lysosomes by the antibiotic concanamycin B in macrophage J774.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Quantification of cathepsins B and L in cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Lysosomal cathepsin B plays an important role in antigen processing, while cathepsin D is involved in degradation of the invariant chain inovalbumin-immunized mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Crystal structure of human osteoclast cathepsin K complex with E-64

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease

1 reference

12 December 2020

The refined 2.15 A X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity

2 references

12 December 2020

https://api.crossref.org/works/10.1016%2FS0065-2776%2802%2980013-X

7 January 2021

Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization

1 reference

12 December 2020

Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules

1 reference

12 December 2020

Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT)

1 reference

12 December 2020

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

1 reference

12 December 2020

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation

1 reference

12 December 2020

Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors

1 reference

12 December 2020

Kinetic analysis of peptide loading onto HLA-DR molecules mediated by HLA-DM.

1 reference

12 December 2020

Cathepsin B cleavage of Ii from class II MHC alpha- and beta-chains

1 reference

12 December 2020

Proteolysis of major histocompatibility complex class II-associated invariant chain is regulated by the alternatively spliced gene product, p41.

1 reference

12 December 2020

Class II major histocompatibility complex molecules of murine dendritic cells: synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture

1 reference

12 December 2020

The HSC73 molecular chaperone: involvement in MHC class II antigen presentation

1 reference

12 December 2020

How MHC class II molecules reach the endocytic pathway

1 reference

12 December 2020

In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen.

1 reference

12 December 2020

Fc epsilon receptor I on dendritic cells delivers IgE-bound multivalent antigens into a cathepsin S-dependent pathway of MHC class II presentation.

1 reference

12 December 2020

Role for intracellular proteases in the processing and transport of class II HLA antigens

1 reference

12 December 2020

Extracellular antigen processing and presentation by immature dendritic cells

1 reference

12 December 2020

Peptidyl fluoromethyl ketones as thiol protease inhibitors

1 reference

12 December 2020

An LI and ML motif in the cytoplasmic tail of the MHC-associated invariant chain mediate rapid internalization

1 reference

12 December 2020

Diversity in MHC class II ovalbumin T cell epitopes generated by distinct proteases

1 reference

12 December 2020

Novel glycosylation of HLA-DRalpha disrupts antigen presentation without altering endosomal localization

1 reference

12 December 2020

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells

1 reference

12 December 2020

In vivo functions mediated by the p41 isoform of the MHC class II-associated invariant chain

1 reference

12 December 2020

Inflammatory mediators regulate cathepsin S in macrophages and microglia: A role in attenuating heparan sulfate interactions

1 reference

12 December 2020

A possible role for Na+,K+-ATPase in regulating ATP-dependent endosome acidification

1 reference

12 December 2020

Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes

1 reference

12 December 2020

Differential expression of the invariant chain in mouse tumor cells: relationship to B lymphoid development

1 reference

12 December 2020

Abundant empty class II MHC molecules on the surface of immature dendritic cells

1 reference

12 December 2020

Delivery of nascent MHC class II-invariant chain complexes to lysosomal compartments and proteolysis of invariant chain by cysteine proteases precedes peptide binding in B-lymphoblastoid cells

1 reference

12 December 2020

Class II antigen processing: analysis of compartments and functions

1 reference

12 December 2020

Endosomal aspartic proteinases are required for invariant-chain processing

1 reference

12 December 2020

Reduction of disulfide bonds within lysosomes is a key step in antigen processing

1 reference

12 December 2020

The proteolytic environment involved in MHC class II-restricted antigen presentation can be modulated by the p41 form of invariant chain

1 reference

12 December 2020

Acidification and disulfide reduction can be sufficient to allow intact proteins to bind class II MHC.

1 reference

12 December 2020

Gene regulation and extracellular functions of procathepsin L.

1 reference

12 December 2020

Role of cathepsin D in antigen presentation of ovalbumin

1 reference

12 December 2020

The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction

1 reference

12 December 2020

The MHC class II-associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail

1 reference

12 December 2020

The high affinity IgE receptor (Fc epsilon RI) mediates IgE-dependent allergen presentation

1 reference

12 December 2020

The vacuolar H(+)-ATPase--one of the most fundamental ion pumps in nature

1 reference

12 December 2020

Cathepsin S regulates the expression of cathepsin L and the turnover of gamma-interferon-inducible lysosomal thiol reductase in B lymphocytes

1 reference

12 December 2020

pH-induced conformational transitions of the propeptide of human cathepsin L. A role for a molten globule state in zymogen activation

1 reference

12 December 2020

10.1016/S0065-2776(02)80013-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12078484%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

2 references

3 February 2017