(Q28674964)

1

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Jian-Jie Zhou

2

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Chao Yu

3

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Ying Xu

4

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Lian-Jun Guo

5

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Hai-Yi Zhang

6

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Fang-Zhou Song

8

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Heng-Yu Fan

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

11 October 2013

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published in

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volume

288

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issue

41

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page(s)

29680-91

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cites work

Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis

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Genetic abolishment of hepatocyte proliferation activates hepatic stem cells

17 March 2017

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CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis

17 March 2017

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Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase

17 March 2017

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VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation

17 March 2017

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Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

17 March 2017

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Tumor-prone phenotype of the DDB2-deficient mice

17 March 2017

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

17 March 2017

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Cullin-RING Ligases as attractive anti-cancer targets

7 April 2017

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Radiosensitization of Cancer Cells by Inactivation of Cullin-RING E3 Ubiquitin Ligases

20 June 2018

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Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells

20 June 2018

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The p21-dependent radiosensitization of human breast cancer cells by MLN4924, an investigational inhibitor of NEDD8 activating enzyme

20 June 2018

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Wild-type tumor repressor protein 53 (Trp53) promotes ovarian cancer cell survival

20 June 2018

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Minireview: animal models and mechanisms of ovarian cancer development

20 June 2018

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The oncogenic phosphatase PPM1D confers cisplatin resistance in ovarian carcinoma cells by attenuating checkpoint kinase 1 and p53 activation.

20 June 2018

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Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

The NEDD8 Conjugation Pathway and Its Relevance in Cancer Biology and Therapy

20 June 2018

1 reference

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Induction of p21-dependent senescence by an NAE inhibitor, MLN4924, as a mechanism of growth suppression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis

20 June 2018

1 reference

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Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

Cul4A is essential for spermatogenesis and male fertility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

SCF E3 ubiquitin ligases as anticancer targets

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

Hepatocyte-specific deletion of DDB1 induces liver regeneration and tumorigenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

DCAF26, an adaptor protein of Cul4-based E3, is essential for DNA methylation in Neurospora crassa

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

CRL4s: the CUL4-RING E3 ubiquitin ligases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

DDB1 is essential for genomic stability in developing epidermis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

Possible role of FLICE-like inhibitory protein (FLIP) in chemoresistant ovarian cancer cells in vitro.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3795265

The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth.

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.495069

Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.495069