(Q28727630)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

H Sobottka

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

C Hempel

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

T Plötz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

W Fischer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

G Schmalzing

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

M Schaefer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

1 September 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

29 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

167

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

48-66

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

29 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3448913/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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17 March 2017

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Evidence for functional P2X4/P2X7 heteromeric receptors

17 March 2017

1 reference

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P2X receptors as cell-surface ATP sensors in health and disease

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Mechanism of ivermectin facilitation of human P2X4 receptor channels

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Molecular physiology of P2X receptors

17 March 2017

1 reference

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Allosteric control of gating and kinetics at P2X(4) receptor channels

17 March 2017

1 reference

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Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

17 March 2017

1 reference

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17 March 2017

1 reference

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Guide to Receptors and Channels (GRAC), 5th edition

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Molecular determinants of ivermectin sensitivity at the glycine receptor chloride channel

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Calcium-dependent block of P2X7 receptor channel function is allosteric

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Activation and regulation of purinergic P2X receptor channels

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

P2X receptors in health and disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Long-term (trophic) purinergic signalling: purinoceptors control cell proliferation, differentiation and death

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Immune cell regulation by autocrine purinergic signalling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Clemastine potentiates the human P2X7 receptor by sensitizing it to lower ATP concentrations.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Experimental characterization and mathematical modeling of P2X7 receptor channel gating.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Electrophysiological classification of P2X7 receptors in rat cultured neocortical astroglia.

3 June 2018

1 reference

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Guidelines for reporting experiments involving animals: the ARRIVE guidelines

3 June 2018

1 reference

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Nicotinic acetylcholine receptor transmembrane mutations convert ivermectin from a positive to a negative allosteric modulator

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Mechanism of action of species-selective P2X(7) receptor antagonists

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Antagonists of the P2X(7) receptor. From lead identification to drug development.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

A P2X receptor from the tardigrade species Hypsibius dujardini with fast kinetics and sensitivity to zinc and copper

3 June 2018

1 reference

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ATP-gated P2X cation-channels

3 June 2018

1 reference

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P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Identification of P2X(4) receptor transmembrane residues contributing to channel gating and interaction with ivermectin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Painful purinergic receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Ivermectin Interaction with transmembrane helices reveals widespread rearrangements during opening of P2X receptor channels

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Modulation of P2X7 receptor functions by polymyxin B: crucial role of the hydrophobic tail of the antibiotic molecule.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

P2X7 receptor expression after ischemia in the cerebral cortex of rats

3 June 2018

1 reference

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Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Modulation of ATP-responses at recombinant rP2X4 receptors by extracellular pH and zinc

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Characterization of ameboid microglia isolated from developing mammalian brain.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

On the distribution of a fluorescent ivermectin probe (4″ 5,7 dimethyl-bodipy proprionylivermectin) in Ascaris membranes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Functional characterization of a P2X receptor from Schistosoma mansoni

3 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Potentiation of native and recombinant P2X7-mediated calcium signaling by arachidonic acid in cultured cortical astrocytes and human embryonic kidney 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Purinergic receptors mediate two distinct glutamate release pathways in hippocampal astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Increase of intracellular Ca2+ by P2X and P2Y receptor-subtypes in cultured cortical astroglia of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Rodent cortical astroglia express in situ functional P2X7 receptors sensing pathologically high ATP concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

P2X7 purinoceptor expression in Xenopus oocytes is not sufficient to produce a pore-forming P2Z-like phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Molecular and functional characterisation of glutamate transporters in rat cortical astrocytes exposed to a defined combination of growth factors during in vitro differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2012.01987.X

Isolation and culture of human macrophages.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

P2X7 receptor-mediated release of excitatory amino acids from astrocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

Anticonvulsant and adverse effects of avermectin analogs in mice are mediated through the gamma-aminobutyric acid(A) receptor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448913

P2X7 receptors in Müller glial cells from the human retina

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22506590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

P2X currents in peritoneal macrophages of wild type and P2X4 -/- mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22506590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2012.01987.X

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22506590%20AND%20SRC:MED&resulttype=core&format=json