(Q28728022)

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Epstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activation

scientific article (publication date: 2012)

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scholarly article

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7 February 2020

Epstein-Barr virus-encoded latent membrane protein 1 impairs G2 checkpoint in human nasopharyngeal epithelial cells through defective Chk1 activation (English)

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7 February 2020

Epstein–Barr virus

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membrane protein

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based on heuristic

inferred from title

6

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7 February 2020

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Chi Man Tsang

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7 February 2020

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Sai Wah Tsao

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7 February 2020

author name string

Wen Deng

1

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7 February 2020

Pei Shin Pang

2

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Pok Man Hau

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7 February 2020

Yim Ling Yip

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language of work or name

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publication date

25 June 2012

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7 February 2020

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7 February 2020

7

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7 February 2020

e39095

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7 February 2020

copyright license

Creative Commons Attribution 4.0 International

25 June 2012

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April 2022 Public Data File from Crossref

copyright status

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Genomic instability--an evolving hallmark of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

17 March 2017

The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

17 March 2017

Chromosome breakage after G2 checkpoint release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

17 March 2017

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

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17 March 2017

CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis

1 reference

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17 March 2017

Epstein-Barr virus: 40 years on

1 reference

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7 April 2017

Down-regulation of EBV-LMP1 radio-sensitizes nasal pharyngeal carcinoma cells via NF-κB regulated ATM expression

1 reference

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3 June 2018

Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpoints

1 reference

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3 June 2018

The G(2) DNA damage checkpoint: could this ancient regulator be the Achilles heel of cancer?

1 reference

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3 June 2018

The ATM tumour suppressor gene is down-regulated in EBV-associated nasopharyngeal carcinoma.

1 reference

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3 June 2018

Regulation of p63 expression in primary and immortalized nasopharyngeal epithelial cells.

1 reference

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3 June 2018

An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells

1 reference

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3 June 2018

Nasopharyngeal carcinoma: molecular biomarker discovery and progress

1 reference

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3 June 2018

Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Extracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Molecular and cytogenetic changes involved in the immortalization of nasopharyngeal epithelial cells by telomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

EBV-associated nasopharyngeal carcinomas: from epidemiology to virus-targeting strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Focus on nasopharyngeal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

A new method for improving metaphase chromosome spreading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

The significance of LMP1 expression in nasopharyngeal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Combined FISH with pan-telomeric PNA and whole chromosome-specific DNA probes to detect complete and incomplete chromosomal exchanges in human lymphocytes

1 reference

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3 June 2018

Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells

1 reference

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3 June 2018

Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice

1 reference

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3 June 2018

Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382577

3 June 2018

Clonal proliferations of cells infected with Epstein-Barr virus in preinvasive lesions related to nasopharyngeal carcinoma

1 reference

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An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

1 reference

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3 June 2018

Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas

1 reference

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3 June 2018

Frequent chromosome 9p losses in histologically normal nasopharyngeal epithelia from southern Chinese

1 reference

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Expression of Epstein-Barr virus-encoded LMP1 and hTERT extends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells

1 reference

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21 January 2018

The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.

1 reference

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21 January 2018

Prevalence of LMP1 deletion variant of Epstein-Barr virus in nasopharyngeal carcinoma and gastric tumors in Hong Kong

1 reference

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21 January 2018

Effects of caffeine and cycloheximide during G2 prophase in control and X-ray-irradiated human lymphocytes

1 reference

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21 January 2018

Pericentromeric instability and spontaneous emergence of human neoacrocentric and minute chromosomes in the alternative pathway of telomere lengthening.

1 reference

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21 January 2018

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10.1371/JOURNAL.PONE.0039095

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7 February 2020

2012PLoSO...739095D

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7 February 2020

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7 February 2020

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