(Q28749276)

4

0 references

author name string

Emidio E Pistilli

2

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Anthony Balduzzi

3

0 references

Jennifer Lachey

5

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Tejvir S Khurana

6

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Rexford S Ahima

Creative Commons Attribution 4.0 International

7

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language of work or name

English

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publication date

15 September 2010

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published in

PLOS One

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volume

5

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page(s)

e12707

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issue

9

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copyright license

start time

15 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways

16 March 2017

1 reference

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Regulation of muscle growth by multiple ligands signaling through activin type II receptors

16 March 2017

1 reference

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Role for Akt3/protein kinase Bgamma in attainment of normal brain size

16 March 2017

1 reference

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

16 March 2017

1 reference

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Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

16 March 2017

1 reference

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Regulation of myostatin activity and muscle growth

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

16 March 2017

1 reference

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy

7 April 2017

1 reference

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Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type

7 April 2017

1 reference

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Pretreatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt.

3 June 2018

1 reference

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The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity

3 June 2018

1 reference

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Smad2 and 3 transcription factors control muscle mass in adulthood.

3 June 2018

1 reference

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Inhibition of ADRP prevents diet-induced insulin resistance

3 June 2018

1 reference

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Myostatin induces p300 degradation to silence cyclin D1 expression through the PI3K/PTEN/Akt pathway

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice

3 June 2018

1 reference

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mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k)

3 June 2018

1 reference

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Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Emerging role of Akt kinase/protein kinase B signaling in pathophysiology of diabetes and its complications

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Unravelling the activation mechanisms of protein kinase B/Akt

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Inhibition of myostatin in adult mice increases skeletal muscle mass and strength

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Induction of cachexia in mice by systemically administered myostatin.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

A Metachromatic Dye-Atpase Method for The Simultaneous Identification of Skeletal Muscle Fiber Types I, IIA, IIB and IIC

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2939888

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

3 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012707

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012707

Down-regulation of Akt/mammalian target of rapamycin signaling pathway in response to myostatin overexpression in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012707

Contractile properties, fiber types, and myosin isoforms in fast and slow muscles of hyperactive Japanese waltzing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012707

Loss of myostatin expression alters fiber-type distribution and expression of myosin heavy chain isoforms in slow- and fast-type skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012707

Myostatin induces cachexia by activating the ubiquitin proteolytic system through an NF-kappaB-independent, FoxO1-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012707

Functional improvement of dystrophic muscle by myostatin blockade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012707

Succinate dehydrogenase activity in fibres classified by myosin ATPase in three hind limb muscles of rat

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20856813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Myostatin gene deletion prevents glucocorticoid-induced muscle atrophy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20856813

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Functional studies of Akt isoform specificity in skeletal muscle in vivo; maintained insulin sensitivity despite reduced insulin receptor substrate-1 expression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20856813