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Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
title
Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation
(English)
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
main subject
Signal transducer and activator of transcription 4
1 reference
stated in
GOA release 2020-03-11
author
Janice S. Blum
series ordinal
5
object named as
Janice S. Blum
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
author name string
Duy Pham
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
Qing Yu
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
Crystal C. Walline
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
Rajarajeswari Muthukrishnan
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
Mark H. Kaplan
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
language of work or name
English
0 references
publication date
15 July 2013
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
published in
Journal of Immunology
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
volume
191
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
issue
2
1 reference
stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
page(s)
902–911
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stated in
PubMed
PubMed ID
23772023
retrieved
14 February 2017
cites work
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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16 March 2017
Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
16 March 2017
Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
1 reference
stated in
PubMed Central
reference URL
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16 March 2017
SnapShot: Histone-modifying enzymes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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16 March 2017
Synergistic function of DNA methyltransferases Dnmt3a and Dnmt3b in the methylation of Oct4 and Nanog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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16 March 2017
Chromatin modifications and their function
1 reference
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PubMed Central
reference URL
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16 March 2017
STAT4: a critical regulator of inflammation in vivo
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PubMed Central
reference URL
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16 March 2017
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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16 March 2017
New nomenclature for chromatin-modifying enzymes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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7 April 2017
Functions of site-specific histone acetylation and deacetylation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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7 April 2017
Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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7 April 2017
STATs shape the active enhancer landscape of T cell populations
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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3 June 2018
Mechanisms regulating regional localization of inflammation during CNS autoimmunity.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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3 June 2018
The histone H3 Lys 27 demethylase JMJD3 regulates gene expression by impacting transcriptional elongation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
De novo DNA methylation is required to restrict T helper lineage plasticity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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3 June 2018
DNA methyltransferase 3a limits the expression of interleukin-13 in T helper 2 cells and allergic airway inflammation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
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3 June 2018
H3K4 tri-methylation provides an epigenetic signature of active enhancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Discrete roles of STAT4 and STAT6 transcription factors in tuning epigenetic modifications and transcription during T helper cell differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Identification of DNA methyltransferase 3a as a T cell receptor-induced regulator of Th1 and Th2 differentiation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Stat4 isoforms differentially regulate inflammation and demyelination in experimental allergic encephalomyelitis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Autoregulation of Th1-mediated inflammation by twist1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Identification of a distant T-bet enhancer responsive to IL-12/Stat4 and IFNgamma/Stat1 signals.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Regulation of signal transducer and activator of transcription signaling by the tyrosine phosphatase PTP-BL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
T helper type 1-specific Brg1 recruitment and remodeling of nucleosomes positioned at the IFN-gamma promoter are Stat4 dependent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
3 June 2018
Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
26 November 2018
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-gamma and interleukin-12.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
26 November 2018
Dynamic changes in histone-methylation 'marks' across the locus encoding interferon-gamma during the differentiation of T helper type 2 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
26 November 2018
Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
26 November 2018
SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
26 November 2018
PU.1 expression delineates heterogeneity in primary Th2 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
26 November 2018
STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3703830
retrieved
26 November 2018
T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23772023
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Roles of IFN-gamma and IFN-alpha in IL-12-induced T helper cell-1 development
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23772023
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23772023
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4049/JIMMUNOL.1203229
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4376708
OpenCitations bibliographic resource ID
4376708
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4376708
PMCID
3703830
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4376708
PubMed ID
23772023
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4376708
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