(Q28817612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

title

Transgenic rat models for mutagenesis and carcinogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

Kenichi Masumura

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

author name string

Naomi Toyoda-Hokaiwado

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

language of work or name

English

0 references

publication date

1 February 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

published in

Genes and Environment

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

volume

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

issue

1

0 references

page(s)

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1186/s41021-016-0072-6

2 April 2020

exact match

0 references

cites work

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Ochratoxin A induces DNA double-strand breaks and large deletion mutations in the carcinogenic target site of gpt delta rats

16 March 2017

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16 March 2017

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16 March 2017

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Effect of increased intake of dietary animal fat and fat energy on oxidative damage, mutation frequency, DNA adduct level and DNA repair in rat colon and liver

16 March 2017

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Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection

16 March 2017

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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion

16 March 2017

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Signatures of mutational processes in human cancer

16 March 2017

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Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice

7 April 2017

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Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents

20 June 2018

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Characterizing Benzo[a]pyrene-induced lacZ mutation spectrum in transgenic mice using next-generation sequencing.

20 June 2018

1 reference

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Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats

20 June 2018

1 reference

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Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats

20 June 2018

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Role of p53 in the progression from ochratoxin A-induced DNA damage to gene mutations in the kidneys of mice

20 June 2018

1 reference

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Genotoxicity of phenacetin in the kidney and liver of Sprague-Dawley gpt delta transgenic rats in 26-week and 52-week repeated-dose studies.

20 June 2018

1 reference

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Cell cycle progression, but not genotoxic activity, mainly contributes to citrinin-induced renal carcinogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Development of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Effects of p53 knockout on ochratoxin A-induced genotoxicity in p53-deficient gpt delta mice

20 June 2018

1 reference

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In vivo genotoxicity of methyleugenol in gpt delta transgenic rats following medium-term exposure

20 June 2018

1 reference

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Possible involvement of genotoxic mechanisms in estragole-induced hepatocarcinogenesis in rats

20 June 2018

1 reference

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Chromatin replication and epigenome maintenance

20 June 2018

1 reference

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Site-specific in vivo mutagenicity in the kidney of gpt delta rats given a carcinogenic dose of ochratoxin A.

20 June 2018

1 reference

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Production of p53 gene knockout rats by homologous recombination in embryonic stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Induction of kidney and liver cancers by the natural food additive madder color in a two-year rat carcinogenicity study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Toward a molecular equivalent dose: use of the medaka model in comparative risk assessment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Mutagenicity of 3-methylcholanthrene, pcb3, and 4-oh-pcb3 in the lung of transgenic bigblue rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Potassium bromate treatment predominantly causes large deletions, but not GC>TA transversion in human cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Dietary effects of soy isoflavones daidzein and genistein on 7,12-dimethylbenz[a]anthracene-induced mammary mutagenesis and carcinogenesis in ovariectomized Big Blue transgenic rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in experimental models

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by leuprorelin, a luteinizing hormone-releasing hormone agonist.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Mutagenicity of comfrey (Symphytum Officinale) in rat liver

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Susceptibility of rats to mammary gland carcinogenesis by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) varies with age and is associated with the induction of differential gene expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Toxicology and Carcinogenesis Studies of Ochratoxin A (CAS No. 303-47-9) in F344/N Rats (Gavage Studies)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Mutagenicity and carcinogenicity in relation to DNA adduct formation in rats fed leucomalachite green

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Studies on mammary carcinogenesis induced by a heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, in mice and rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

P53+/- hemizygous knockout mouse: overview of available data

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Insulin, insulin-like growth factors and colon cancer: a review of the evidence

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Prostate carcinomas developing in transgenic rats with SV40 T antigen expression under probasin promoter control are strictly androgen dependent

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Recent advances in the protocols of transgenic mouse mutation assays.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Epigenetic mechanisms of nickel carcinogenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Spi(-) selection: An efficient method to detect gamma-ray-induced deletions in transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Nickel subsulfide is genotoxic in vitro but shows no mutagenic potential in respiratory tract tissues of BigBlue rats and Muta Mouse mice in vivo after inhalation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Hepatic lacI and cII mutation in transgenic (lambdaLIZ) rats treated with dimethylnitrosamine.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Does tamoxifen cause cancer in humans?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Species-specific differences in hepatic mutant frequency and mutational spectrum among lambda/lacI transgenic rats and mice following exposure to aflatoxin B1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Transgenic hepatocarcinogenesis in the rat

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Site-specific cell proliferation in renal tubular cells by the renal tubular carcinogen tris(2,3-dibromopropyl)phosphate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Development of a rat cell line containing stably integrated copies of a lambda/lacI shuttle vector

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Comparative carcinogenic effects of nickel subsulfide, nickel oxide, or nickel sulfate hexahydrate chronic exposures in the lung

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Comparisons between carcinogenic potency and mutagenic potency to Salmonella in a series of derivatives of 4-dimethylaminoazobenzene (DAB).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Carcinogenic activity of analogs of p-dimethylaminoazobenzene. VI. Activity of the benzimidazole and benzthiazole analogs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats--an approach for a new medium-term bioassay system.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Carcinogenicity in rats of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

The genetic toxicity of human carcinogens and its implications

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Metabolism, disposition, and mutagenicity of 2,6-diaminotoluene, a mutagenic noncarcinogen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Efficient rescue of integrated shuttle vectors from transgenic mice: a model for studying mutations in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Health effects of exposure to diesel exhaust particles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Oval cell proliferation and the origin of small hepatocytes in liver injury induced by D-galactosamine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Overview from the International Conference on Long-Term Tamoxifen Therapy for Breast Cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Tumors of Sprague-Dawley rats induced by long-term feeding of phenacetin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Liver Tumors and Steroid Hormones in Rats and Mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

A mammalian spot test: Induction of genetic alterations in pigment cells of mouse embryos with X-rays and chemical mutagens

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Threshold effects in genetic toxicity: perspective of chemicals regulation in Germany.

20 June 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

The use of shuttle vectors for mutation analysis in transgenic mice and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Novel transgenic rat for in vivo genotoxicity assays using 6-thioguanine and Spi- selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Interpretation of mutational spectra from different genes: analyses of PhIP-induced mutational specificity in the lacI and cII transgenes from colon of Big Blue rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Extent of CpG methylation is not proportional to the in vivo spontaneous mutation frequency at transgenic loci in Big Blue rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutation induction by mechanical irritation caused by uracil-induced urolithiasis in Big Blue rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutant frequency and molecular analysis of in vivo lacI mutations in the bone marrow of Big Blue rats treated with 7, 12-dimethylbenz[a]anthracene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue(R) rats treated with 7, 12-dimethylbenz[a]anthracene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Comparison of hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene-treated Big Blue rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Organ differences in the enhancing potential of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine on carcinogenicity in the prostate, colon and pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Preferential induction of guanine deletion at 5'-GGGA-3' in rat mammary glands by 2-amino- 1-methyl-6-phenylimidazo[4,5-b]pyridine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutations induced by 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) in cecum and proximal and distal colon of lacI transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Tris(2,3-dibromopropyl)phosphate causes a gradient of mutations in the cortex and outer and inner medullas of the kidney of lacI transgenic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Relationship of carcinogenicity and cellular proliferation induced by mutagenic noncarcinogens vs carcinogens. III. Organophosphate pesticides vs tris(2,3-dibromopropyl)phosphate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Evaluation of the genotoxicity of tamoxifen in the liver and kidney of F344 gpt delta transgenic rat in 3-week and 13-week repeated dose studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Absence of in vivo genotoxicity of 3-monochloropropane-1,2-diol and associated fatty acid esters in a 4-week comprehensive toxicity study using F344 gpt delta rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Tumorigenicity of citrinin in male F344 rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

A 13-week repeated dose study of three 3-monochloropropane-1,2-diol fatty acid esters in F344 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Relative oral bioavailability of 3-MCPD from 3-MCPD fatty acid esters in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Combined application of comprehensive analysis for DNA modification and reporter gene mutation assay to evaluate kidneys of gpt delta rats given madder color or its constituents

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Carcinogenicity of malachite green chloride and leucomalachite green in B6C3F1 mice and F344 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Analysis of mutations and bone marrow micronuclei in Big Blue rats fed leucomalachite green

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

No-observed effect levels for carcinogenicity and for in vivo mutagenicity of a genotoxic carcinogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Lack of mutagenic and toxic effects of low dose potassium bromate on kidneys in the Big Blue rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Quantitative dose-response analysis of ethyl methanesulfonate genotoxicity in adult gpt-delta transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Quantitative approaches for assessing dose-response relationships in genetic toxicology studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Chemoprotection against N-nitrosomethylbenzylamine-induced mutation in the rat esophagus

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Endogenous estrogen status, but not genistein supplementation, modulates 7,12-dimethylbenz[a]anthracene-induced mutation in the liver cII gene of transgenic big blue rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Effects of daidzein, genistein, and 17beta-estradiol on 7,12-dimethylbenz[a]anthracene-induced mutagenicity and uterine dysplasia in ovariectomized rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Sex-specific induction of mutations by PhIP in the kidney of male and female rats and its modulation by conjugated linoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Sucrose and IQ induced mutations in rat colon by independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Sucrose, glucose and fructose have similar genotoxicity in the rat colon and affect the metabolome

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

The effect of dietary restriction on PhIP-induced mutation in the distal colon and B[a]P- and ENU-induced mutation in the liver of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Benzo[a]pyrene-enhanced mutagenesis by asbestos in the lung of lambda-lacI transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

The dioxin TCDD protects against aflatoxin-induced mutation in female rats, but not in male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutational spectra of tamoxifen-induced mutations in the livers of lacI transgenic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Tamoxifen induces G:C-->T:A mutations in the cII gene in the liver of lambda/lacI transgenic rats but not at 5'-CpG-3' dinucleotide sequences as found in the lacI transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Tamoxifen mutagenesis and carcinogenesis in livers of lambda/lacI transgenic rats: selective influence of phenobarbital promotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutations induced by carcinogenic doses of aristolochic acid in kidney of Big Blue transgenic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutations induced by the carcinogenic pyrrolizidine alkaloid riddelliine in the liver cII gene of transgenic big blue rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Differential mutagenicity of riddelliine in liver endothelial and parenchymal cells of transgenic big blue rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Bromate induces loss of heterozygosity in the Thymidine kinase gene of L5178Y/Tk+/−-3.7.2C mouse lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Possible participation of oxidative stress in causation of cell proliferation and in vivo mutagenicity in kidneys of gpt delta rats treated with potassium bromate

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutagenesis by asbestos in the lung of lambda-lacI transgenic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutagenesis by man-made mineral fibres in the lung of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutagenicity of TCDD in Big Blue transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Increase in mutation frequency in lung of Big Blue rat by exposure to diesel exhaust.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

DNA damage in lung after oral exposure to diesel exhaust particles in Big Blue rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Genotoxic effects of bitumen fumes in Big Blue transgenic rat lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

4-monochlorobiphenyl (PCB3) induces mutations in the livers of transgenic Fisher 344 rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mammary carcinomas induced in human c-Ha-ras proto-oncogene transgenic rats are estrogen-independent, but responsive to d-limonene treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Transgenic rats carrying copies of the human c-Ha-ras proto-oncogene exhibit enhanced susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine bladder carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Transgenic rats carrying human c-Ha-ras proto-oncogene are highly susceptible to N-nitrosomethylbenzylamine induction of esophageal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Age-dependent histopathological findings in the prostate of probasin/SV40 T antigen transgenic rats: lack of influence of carcinogen or testosterone treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Connexin 32 dominant-negative mutant transgenic rats are resistant to hepatic damage by chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Transgenic disruption of gap junctional intercellular communication enhances early but not late stage hepatocarcinogenesis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Both early and late stages of hepatocarcinogenesis are enhanced in Cx32 dominant negative mutant transgenic rats with disrupted gap junctional intercellular communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Ductal origin of pancreatic adenocarcinomas induced by conditional activation of a human Ha-ras oncogene in rat pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Generation of site-specific mutations in the rat genome via CRISPR/Cas9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2-ethylhexyl)phthalate

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

The genotoxicity of acrylamide and glycidamide in big blue rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutational analysis of the liver, colon and kidney of Big Blue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in colon and liver of Big Blue rats: role of DNA adducts, strand breaks, DNA repair and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Modulation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mutation in the cecum and colon of big blue rats by conjugated linoleic acid and 1,2-dithiole-3-thione

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Effect of conjugated linoleic acid on the formation of spontaneous and PhIP-induced mutation in the colon and cecum of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Tissue-specific microRNA responses in rats treated with mutagenic and carcinogenic doses of aristolochic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue® rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

No-effect level in the mutagenic activity of the drug cyproterone acetate in rat liver. Part II. Multiple dose treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mutagenicity of the potent rat hepatocarcinogen 6BT to the liver of transgenic (lacI) rats: consideration of a reduced mutation assay protocol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

DNA adduct formation and molecular analysis of in vivo lacI mutations in the mammary tissue of Big Blue rats treated with 7, 12-dimethylbenz[a]anthracene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

17 Beta-estradiol and not genistein modulates lacI mutant frequency and types of mutation induced in the heart of ovariectomized big blue rats treated with 7, 12-dimethylbenz[a]anthracene

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Genotoxicity of furan in Big Blue rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Benzo[a]pyrene-enhanced mutagenesis by man-made mineral fibres in the lung of lamda-lacI transgenic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Gene- and tissue-specificity of mutation in Big Blue rats treated with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Induction of lacI mutations in Big Blue rats treated with tamoxifen and alpha-hydroxytamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Short-term dosing of alpha-hydroxytamoxifen results in DNA damage but does not lead to liver tumours in female Wistar/Han rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

High dietary intake of sodium selenite does not affect gene mutation frequency in rat colon and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS41021-016-0072-6

The mutagenic potential of duodenoesophageal reflux.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Bioassay of 2,6-Toluenediamine Dihydrochloride for Possible Carcinogenicity (CAS No. 15481-70-6).

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Some traditional herbal medicines, some mycotoxins, naphthalene and styrene.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

NTP Toxicology and Carcinogenesis Studies of Methyleugenol (CAS NO. 93-15-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

A sucrose-rich diet induces mutations in the rat colon.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Distinct spectrum of mutations induced by crocidolite asbestos: clue for 8-hydroxydeoxyguanosine-dependent mutagenesis in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Dose dependent induction of DNA adducts, gene mutations, and cell proliferation by the antiandrogenic drug cyproterone acetate in rat liver

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Hepatic gene mutations induced in Big Blue rats by both the potent rat liver azo-carcinogen 6BT and its reported noncarcinogenic analogue 5BT.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

Effects of chronic administration of tamoxifen and toremifene on DNA adducts in rat liver, kidney, and uterus.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

A new transgenic mouse mutagenesis test system using Spi- and 6-thioguanine selections

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289047

26 November 2018

1 reference

12 December 2020

Effects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 rats

1 reference

12 December 2020

Induction of renal cell tumors in F-344 rats by oral administration of potassium bromate, a food additive

1 reference

12 December 2020

Identification of catechol and hydroquinone metabolites of 4-monochlorobiphenyl

1 reference

12 December 2020

An animal model of preclinical diagnosis of pancreatic ductal adenocarcinomas

1 reference

12 December 2020

Effect of gamma radiation at high- and low-dose rate on a novel in vivo mutation assay in mouse intestine

1 reference

12 December 2020

Acrylamide genotoxicity in young versus adult gpt delta male rats

1 reference

12 December 2020

Prostate mutations in rats induced by the suspected human carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

1 reference

12 December 2020

Tamoxifen causes gene mutations in the livers of lambda/lacI transgenic rats

1 reference

12 December 2020

A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

1 reference

12 December 2020

Transgenic rats carrying human c-Ha-ras proto-oncogenes are highly susceptible to N-methyl-N-nitrosourea mammary carcinogenesis

1 reference

12 December 2020

Bioassay of 2,4-diaminotoluene for possible carcinogenicity

1 reference

12 December 2020

1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity

1 reference

12 December 2020

10.1186/S41021-016-0072-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28174618%20AND%20SRC:MED&resulttype=core&format=json

2 April 2020

1 reference