(Q29544441)

English

The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis

scientific article (publication date: 14 April 2016)

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scholarly article

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Europe PubMed Central

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1 April 2020

The epigenetic modifier JMJD6 is amplified in mammary tumors and cooperates with c-Myc to enhance cellular transformation, tumor progression, and metastasis (English)

2 references

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https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

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1 April 2020

tumor progression

1 reference

based on heuristic

inferred from title

2

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1 April 2020

author name string

Olga Aprelikova

1

2 references

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https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

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1 April 2020

Constance Brignatz-Guittard

4

2 references

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22 April 2017

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1 April 2020

Justin Han

5

2 references

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https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

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1 April 2020

Tinghu Qiu

6

2 references

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22 April 2017

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1 April 2020

Min Zhu

9

2 references

DOI.org query endpoint

https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

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1 April 2020

Lara H El Touny

3

1 reference

Europe PubMed Central

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1 April 2020

Howard H Yang

7

1 reference

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1 April 2020

Maxwell P Lee

8

1 reference

Europe PubMed Central

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1 April 2020

Jeffrey E Green

10

1 reference

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1 April 2020

publication date

14 April 2016

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22 April 2017

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1 April 2020

Clinical Epigenetics

2 references

DOI.org query endpoint

https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

Europe PubMed Central

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1 April 2020

8

2 references

DOI.org query endpoint

https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27081402%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1

1 reference

DOI.org query endpoint

https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

38

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27081402%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4831179/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1186/s13148-016-0205-6

0 references

The mechanisms behind the therapeutic activity of BET bromodomain inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

BRD4 short isoform interacts with RRP1B, SIPA1 and components of the LINC complex at the inner face of the nuclear membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

TDRD3 is an effector molecule for arginine-methylated histone marks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

c-Myc regulates transcriptional pause release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Regulation of estrogen rapid signaling through arginine methylation by PRMT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

JMJD6 is a histone arginine demethylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Quantitative proteomic analysis of myc-induced apoptosis: a direct role for Myc induction of the mitochondrial chloride ion channel, mtCLIC/CLIC4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Myc pathways provoking cell suicide and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Repeated observation of breast tumor subtypes in independent gene expression data sets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Induction of apoptosis in fibroblasts by c-myc protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

22 April 2017

Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Role of JMJD6 in Breast Tumourigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Identification by array comparative genomic hybridization of a new amplicon on chromosome 17q highly recurrent in BRCA1 mutated triple negative breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Systems consequences of amplicon formation in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Jumonji domain containing protein 6 (Jmjd6) modulates splicing and specifically interacts with arginine-serine-rich (RS) domains of SR- and SR-like proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

JMJD6 promotes colon carcinogenesis through negative regulation of p53 by hydroxylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

JMJD6 regulates ERα methylation on arginine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

TNFSF15 inhibits vasculogenesis by regulating relative levels of membrane-bound and soluble isoforms of VEGF receptor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Transcriptional amplification in tumor cells with elevated c-Myc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

H4R3 methylation facilitates beta-globin transcription by regulating histone acetyltransferase binding and H3 acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Apoptotic signaling by c-MYC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Histone arginine methylation and its dynamic regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

The Septin 9 (MSF) gene is amplified and overexpressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

c-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

c-Myc in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

The C3(1)/SV40 T-antigen transgenic mouse model of mammary cancer: ductal epithelial cell targeting with multistage progression to carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Chromosomal alterations in ductal carcinomas in situ and their in situ recurrences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

MYC oncogenes and human neoplastic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

c-myc oncogene expression in estrogen-dependent and -independent breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Mediation of c-Myc-induced apoptosis by p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Apoptosis induced by c-myc overexpression is dependent on growth conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

Oncogene amplification in tumor cells.

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

3 June 2018

https://api.crossref.org/works/10.1186%2FS13148-016-0205-6

21 January 2018

Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling

1 reference

https://api.crossref.org/works/10.1186%2FS13148-016-0205-6

21 January 2018

Haploid loss of Ki-ras delays mammary tumor progression in C3 (1)/SV40 Tag transgenic mice.

1 reference

https://api.crossref.org/works/10.1186%2FS13148-016-0205-6

21 January 2018

High expression of JMJD6 predicts unfavorable survival in lung adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1186%2FS13148-016-0205-6

21 January 2018

Global search for chromosomal abnormalities in infiltrating ductal carcinoma of the breast using array-comparative genomic hybridization

1 reference

https://api.crossref.org/works/10.1186%2FS13148-016-0205-6

21 January 2018

A recurring pattern of chromosomal aberrations in mammary gland tumors of MMTV-cmyc transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4831179

26 November 2018

Mouse models for breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27081402

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27081402

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/27081402

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of Ki-ras and elevation of MAP kinase activity during mammary tumor progression in C3(1)/SV40 Tag transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27081402

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13148-016-0205-6

3 references

DOI.org query endpoint

https://doi.org/10.1186%2FS13148-016-0205-6

22 April 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27081402%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Dimensions Publication ID

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27081402%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27081402%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

ResearchGate publication ID

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