(Q29617201)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia (English)

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

main subject

acute myeloid leukemia

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Harald Herrmann

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Peter Valent

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Christopher R. Vakoc

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

9

Katharina Blatt

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Junwei Shi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Eric Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Amy R Rappaport

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Edward A Sison

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Daniel Magoon

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Jun Qi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Mark Wunderlich

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Meredith J Taylor

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Christopher Johns

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Agustin Chicas

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

James C Mulloy

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Scott C Kogan

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Patrick Brown

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

James E Bradner

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Scott W Lowe

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

9 February 2020

language of work or name

1 reference

30 April 2017

publication date

3 August 2011

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

478

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

7370

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

524-528

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

Suppression of inflammation by a synthetic histone mimic

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

DNMT3A Mutations in Acute Myeloid Leukemia

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Selective inhibition of BET bromodomains

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

The miR-17-92 microRNA polycistron regulates MLL leukemia stem cell potential by modulating p21 expression

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Mutation in TET2 in myeloid cancers

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Using galaxy to perform large-scale interactive data analyses

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Brd4 recruits P-TEFb to chromosomes at late mitosis to promote G1 gene expression and cell cycle progression

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Proposals for the Classification of the Acute Leukaemias French-American-British (FAB) Co-operative Group

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Leukaemogenesis: more than mutant genes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Mouse models of human AML accurately predict chemotherapy response

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Stem cell concepts renew cancer research

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

H3K79 methylation profiles define murine and human MLL-AF4 leukemias

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Modelling Myc inhibition as a cancer therapy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Menin critically links MLL proteins with LEDGF on cancer-associated target genes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

The molecular basis of leukemia

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

The transcriptional program of a human B cell line in response to Myc

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Regulation of the resident chromosomal copy of c-myc by c-Myb is involved in myeloid leukemogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Reversible tumorigenesis by MYC in hematopoietic lineages

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328300

Model systems for examining effects of leukemia-associated oncogenes in primary human CD34+ cells via retroviral transduction

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE10334

In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE10334

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21814200

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 February 2020

1030076294

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

3 references

30 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21814200%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21814200

9 February 2020

PubMed publication ID

3 references

30 April 2017