(Q29617473)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

1 reference

Fingar DC

1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

Blenis J

series ordinal

2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

language of work or name

1 reference

30 April 2017

publication date

19 April 2004

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

volume

23

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

page(s)

3151-71

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

issue

18

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

Immunopharmacology of rapamycin

30 April 2017

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p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

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FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse

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The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites

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Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

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Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

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Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

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Identification and characterization of a mitogen-activated S6 kinase

21 January 2018

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Coordination of growth with cell division in the yeast Saccharomyces cerevisiae

21 January 2018

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Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

21 January 2018

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Cytoplasmic-nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation

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Coordinate regulation of translation by the PI 3-kinase and mTOR pathways

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Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs

21 January 2018

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A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization

21 January 2018

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Sirolimus-Eluting Stents versus Standard Stents in Patients with Stenosis in a Native Coronary Artery

21 January 2018

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B cell receptor-associated protein alpha4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A

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Regulation of protein phosphatase 2A catalytic activity by alpha4 protein and its yeast homolog Tap42

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Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

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The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif

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Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background

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FKBP12-Rapamycin-associated Protein (FRAP) Autophosphorylates at Serine 2481 under Translationally Repressive Conditions

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An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

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The TOR kinases link nutrient sensing to cell growth

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The Rapamycin and FKBP12 Target (RAFT) Displays Phosphatidylinositol 4-Kinase Activity

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21 January 2018

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The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

21 January 2018

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Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells

21 January 2018

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Akt signaling mediates postnatal heart growth in response to insulin and nutritional status

21 January 2018

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The mRNA 5' cap-binding protein eIF4E and control of cell growth

21 January 2018

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Genetic control of cell size

21 January 2018

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Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1)

21 January 2018

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Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

21 January 2018

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The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake

21 January 2018

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Genetics: influence of TOR kinase on lifespan in C. elegans

21 January 2018

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The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression

21 January 2018

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

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4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

21 January 2018

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The genetic control of organ growth: insights from Drosophila.

21 January 2018

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Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies.

21 January 2018

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Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A.

21 January 2018

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FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins

21 January 2018

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Cdc42 stimulates RNA splicing via the S6 kinase and a novel S6 kinase target, the nuclear cap-binding complex

21 January 2018

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Identification of TOR signaling complexes: more TORC for the cell growth engine

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7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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7 January 2021

The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors

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7 January 2021

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

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7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

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7 January 2021

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

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7 January 2021

Control of p70 s6 kinase by kinase activity of FRAP in vivo

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7 January 2021

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

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7 January 2021

The phosphoinositide 3-kinase pathway

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7 January 2021

Phospholipase D confers rapamycin resistance in human breast cancer cells

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7 January 2021

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

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7 January 2021

Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP

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7 January 2021

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

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7 January 2021

A nutrient sensor mechanism controls Drosophila growth.

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7 January 2021

Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression

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7 January 2021

Mammalian TOR: a homeostatic ATP sensor

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7 January 2021

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

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7 January 2021

Inhibition of intimal thickening after balloon angioplasty in porcine coronary arteries by targeting regulators of the cell cycle

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7 January 2021

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

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7 January 2021

Regulation of translation initiation by FRAP/mTOR

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

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7 January 2021

AMP-activated protein kinase: the energy charge hypothesis revisited

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7 January 2021

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

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7 January 2021

Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

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7 January 2021

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

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7 January 2021

The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

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7 January 2021

Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation

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7 January 2021

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

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7 January 2021

TSC2 mediates cellular energy response to control cell growth and survival

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7 January 2021

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7 January 2021

A C. elegans mutant that lives twice as long as wild type

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7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

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7 January 2021

A possible linkage between AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) signalling pathway

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7 January 2021

A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice

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7 January 2021

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

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7 January 2021

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

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7 January 2021

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

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7 January 2021

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

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7 January 2021

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

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7 January 2021

Rheb fills a GAP between TSC and TOR.

1 reference

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7 January 2021

United at last: the tuberous sclerosis complex gene products connect the phosphoinositide 3-kinase/Akt pathway to mammalian target of rapamycin (mTOR) signalling

1 reference

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7 January 2021

Drosophila S6 kinase: a regulator of cell size.

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7 January 2021

Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies

1 reference

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7 January 2021

Coordination of growth and cell division in the Drosophila wing.

1 reference

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7 January 2021

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.

1 reference

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7 January 2021

The ATRs, ATMs, and TORs are giant HEAT repeat proteins.

1 reference

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7 January 2021

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size.

1 reference

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7 January 2021

Phosphorylation and activation of p70s6k by PDK1

1 reference

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7 January 2021

Modulation of apoptosis, proliferation, and p27 expression in a porcine coronary angioplasty model

1 reference

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7 January 2021

Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38

1 reference

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7 January 2021

Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling

1 reference

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7 January 2021

Insulin signalling and the regulation of glucose and lipid metabolism

1 reference

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7 January 2021

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1 reference

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7 January 2021

A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin

1 reference

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7 January 2021

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.

1 reference

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7 January 2021

The coupling of cell growth to the cell cycle.

1 reference

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7 January 2021

Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin

1 reference

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7 January 2021

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

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7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207542

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

262722

1016470855

0 references

262722

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15094765

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017