(Q30010014)

English

Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1.

scientific article published on 9 August 2012

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Europe PubMed Central

PubMed publication ID

21 May 2017

Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

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author name string

Hong Chang

1

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Laurent Balenci

2

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Nadia Okolowsky

3

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

William J Muller

4

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Paul A Hamel

5

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Europe PubMed Central

PubMed publication ID

21 May 2017

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publication date

9 August 2012

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Europe PubMed Central

PubMed publication ID

21 May 2017

Developmental Biology

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Europe PubMed Central

PubMed publication ID

21 May 2017

370

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Europe PubMed Central

PubMed publication ID

21 May 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

187-197

1 reference

Europe PubMed Central

PubMed publication ID

21 May 2017

Patched1 functions as a gatekeeper by promoting cell cycle progression

1 reference

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The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

1 reference

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The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development

1 reference

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Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling

1 reference

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Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor

1 reference

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Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors

1 reference

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7 January 2021

Patched1 interacts with cyclin B1 to regulate cell cycle progression

1 reference

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7 January 2021

Identification of an unexpected link between the Shh pathway and a G2/M regulator, the phosphatase CDC25B

1 reference

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Mammary gland development and tumorigenesis in estrogen receptor knockout mice

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Noncanonical Hedgehog signaling

1 reference

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Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling

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Disruption of the mouse oestrogen receptor gene: resulting phenotypes and experimental findings.

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Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

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Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands

1 reference

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Dishevelled: The hub of Wnt signaling

1 reference

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Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

1 reference

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Altered neural cell fates and medulloblastoma in mouse patched mutants

1 reference

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Protecting the hedgerow: p53 and hedgehog pathway interactions

1 reference

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Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation

1 reference

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Structure-function-folding relationship in a WW domain

1 reference

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Hedgehog signalling: emerging evidence for non-canonical pathways

1 reference

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c-Src-null mice exhibit defects in normal mammary gland development and ERalpha signaling

1 reference

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Wnt signal transduction pathways

1 reference

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Insights from the study of animals lacking functional estrogen receptor

1 reference

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7 January 2021

Reduced white fat mass in adult mice bearing a truncated Patched 1

1 reference

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Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

1 reference

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Early and multifocal tumors in breast, salivary, Harderian and epididymal tissues developed in MMTY-Neu transgenic mice

1 reference

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Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide.

1 reference

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A spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc)

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.07.027

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Biochemical evidence that patched is the Hedgehog receptor

1 reference

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Regulation of patched by sonic hedgehog in the developing neural tube

1 reference

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Hedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active Site

1 reference

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Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

1 reference

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Ptch1 is required locally for mammary gland morphogenesis and systemically for ductal elongation

1 reference

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Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia

1 reference

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Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

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Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1

1 reference

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7 January 2021

Boc is a receptor for sonic hedgehog in the guidance of commissural axons

1 reference

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Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate

1 reference

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Phage display selection of ligand residues important for Src homology 3 domain binding specificity

1 reference

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Hedgehog signal transduction: signal integration and cross talk in development and cancer

1 reference

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Pathways of signal transduction employed by vertebrate Hedgehogs

1 reference

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The GLI-Kruppel family of human genes

1 reference

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GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity

1 reference

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Sonic hedgehog signaling is essential for hair development

1 reference

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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

1 reference

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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

1 reference

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Characterization of a novel protein-binding module--the WW domain

1 reference

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Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse

1 reference

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smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

1 reference

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Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened

1 reference

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Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice

1 reference

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Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/-) mice

1 reference

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Induction of mammary epithelial hyperplasias and mammary tumors in transgenic mice expressing a murine mammary tumor virus/activated c-src fusion gene

1 reference

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Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway

1 reference

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Structural basis for the binding of proline-rich peptides to SH3 domains

1 reference

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Cyclopamine inhibition of human breast cancer cell growth independent of Smoothened (Smo).

1 reference

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Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node

1 reference

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7 January 2021

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10.1016/J.YDBIO.2012.07.027

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https://api.fatcat.wiki/v0/release/umjurmqujve3bli2fe47lbrioi

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