Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q28594387)
Watch
English
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node
scientific journal article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
title
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node
(English)
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
main subject
Smoothened, frizzled class receptor
1 reference
stated in
GOA release 2020-03-11
Indian hedgehog
1 reference
stated in
GOA release 2020-03-11
Patched 1
1 reference
stated in
GOA release 2020-03-11
Sonic hedgehog
1 reference
stated in
GOA release 2020-03-11
author name string
X. M. Zhang
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
M. Ramalho-Santos
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
A. P. McMahon
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
language of work or name
English
0 references
publication date
27 July 2001
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
published in
Cell
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
volume
106
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
page(s)
781–792
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
issue
2
1 reference
stated in
PubMed
PubMed ID
11517919
retrieved
31 January 2017
cites work
Cloning of a mouse smoothened cDNA and expression patterns of hedgehog signalling molecules during chondrogenesis and cartilage differentiation in clonal mouse EC cells, ATDC5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sertoli cell signaling by Desert hedgehog regulates the male germline
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple tissue interactions and signal transduction pathways control somite myogenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of left-right determination in vertebrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of two patched receptors for the vertebrate hedgehog protein family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual roles for patched in sequestering and transducing Hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role for Sonic hedgehog during hair follicle morphogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between asymmetric nodal expression and the direction of embryonic turning
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt signaling and the activation of myogenesis in mammals.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sclerotome induction and differentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog promotes neuronal differentiation of murine spinal cord precursors and collaborates with neurotrophin 3 to induce Islet-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role of the cryptic gene in the correct establishment of the left-right axis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered neural cell fates and medulloblastoma in mouse patched mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The world according to hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of positive and negative signals in somite patterning
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A molecular pathway determining left-right asymmetry in chick embryogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog is essential to foregut development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of limb and brain patterning in early mouse embryos by ultrasound-guided injection of Shh-expressing cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vertebrate heart development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo regulation of somite differentiation and proliferation by Sonic Hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemical evidence that patched is the Hedgehog receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A duplicated zone of polarizing activity in polydactylous mouse mutants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positional specification of ventricular myosin light chain 2 expression in the primitive murine heart tube
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog regulates branching morphogenesis in the mammalian lung
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pitx2 participates in the late phase of the pathway controlling left-right asymmetry.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog signal transduction in the posterior compartment of the Drosophila wing imaginal disc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of left-right patterning in mice by growth/differentiation factor-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pitx2 determines left-right asymmetry of internal organs in vertebrates.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The EGF-CFC gene family in vertebrate development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sonic hedgehog signaling is essential for hair development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activating Smoothened mutations in sporadic basal-cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900385-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(01)00385-3
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
826464
OpenCitations bibliographic resource ID
826464
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
826464
PubMed ID
11517919
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
826464
11440720
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
826464
ResearchGate publication ID
11899987
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit