(Q28504970)

24 January 2017

title

Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1 (English)

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Myelocytomatosis oncogene

24 January 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Erica Nieuwenhuis

1

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24 January 2017

Paul C. Barnfield

2

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24 January 2017

Shigeru Makino

3

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24 January 2017

Chi-Chung Hui

4

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24 January 2017

language of work or name

English

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publication date

15 August 2007

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24 January 2017

published in

Developmental Biology

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24 January 2017

volume

308

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24 January 2017

issue

2

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24 January 2017

page(s)

547–560

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Pathways to improving skin regeneration

24 January 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis

7 January 2021

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Patched1 functions as a gatekeeper by promoting cell cycle progression

7 January 2021

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c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny

7 January 2021

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Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome

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Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice

7 January 2021

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Several PATCHED1 missense mutations display activity in patched1-deficient fibroblasts

7 January 2021

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Patched1 interacts with cyclin B1 to regulate cell cycle progression

7 January 2021

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Constitutive activation of the shh-ptc1 pathway by a patched1 mutation identified in BCC.

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Inhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migration

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Essential role for Sonic hedgehog during hair follicle morphogenesis

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Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein

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Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1

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Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis

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Location of gene for Gorlin syndrome

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7 January 2021

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7 January 2021

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Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9

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7 January 2021

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7 January 2021

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Basal cell carcinomas in mice overexpressing Gli2 in skin

7 January 2021

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The magnitude of hedgehog signaling activity defines skin tumor phenotype

7 January 2021

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Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome

7 January 2021

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The secret life of the hair follicle

7 January 2021

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Identification of c-MYC as a target of the APC pathway

7 January 2021

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Insight into the pathogenesis of sporadic basal cell carcinoma

7 January 2021

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Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease

7 January 2021

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The Drosophila patched gene encodes a putative membrane protein required for segmental patterning

7 January 2021

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Interfollicular epidermal stem cells: identification, challenges, potential.

7 January 2021

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The role of p63 in development and differentiation of the epidermis

7 January 2021

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The C-terminal tail of the Hedgehog receptor Patched regulates both localization and turnover

7 January 2021

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A spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc)

7 January 2021

1 reference

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Basal cell carcinoma and its development: insights from radiation-induced tumors in Ptch1-deficient mice

7 January 2021

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Biochemical evidence that patched is the Hedgehog receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog

7 January 2021

1 reference

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Hedgehog signaling and congenital malformations

7 January 2021

1 reference

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Mice with a targeted mutation of patched2 are viable but develop alopecia and epidermal hyperplasia

7 January 2021

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Boc is a receptor for sonic hedgehog in the guidance of commissural axons

7 January 2021

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Hair cycle regulation of Hedgehog signal reception

7 January 2021

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Basal cell carcinomas in mice overexpressing sonic hedgehog

7 January 2021

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Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background

7 January 2021

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Keratinocyte stem cells, label-retaining cells and possible genome protection mechanisms

7 January 2021

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Sonic hedgehog signaling is essential for hair development

7 January 2021

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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

Deregulated expression of c-Myc depletes epidermal stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

Endogenous Myc controls mammalian epidermal cell size, hyperproliferation, endoreplication and stem cell amplification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2007.06.016

10.1016/J.YDBIO.2007.06.016

7 January 2021

Identifiers

DOI

0 references

1 reference