(Q34611868)

3 August 2017

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title

Getting under the skin of epidermal morphogenesis (English)

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3 August 2017

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1

Elaine Fuchs

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3 August 2017

Srikala Raghavan

2

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PubMed ID

11972157

3 August 2017

language of work or name

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1 March 2002

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3 August 2017

Nature Reviews Genetics

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3 August 2017

3

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3 August 2017

199-209

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3 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrg758

3 August 2017

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p63 is a p53 homologue required for limb and epidermal morphogenesis

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IKKalpha controls formation of the epidermis independently of NF-kappaB.

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Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.

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Inhibition of skin development by targeted expression of a dominant-negative retinoic acid receptor

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Molecular basis for the rhino (hrrh-8J) phenotype: a nonsense mutation in the mouse hairless gene

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Regulation of a human epidermal keratin gene: sequences and nuclear factors involved in keratinocyte-specific transcription

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Transcription factor AP2 and its role in epidermal-specific gene expression

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The proximal promoter of the mouse loricrin gene contains a functional AP-1 element and directs keratinocyte-specific but not differentiation-specific expression

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The transglutaminase 1 enzyme is variably acylated by myristate and palmitate during differentiation in epidermal keratinocytes

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Identification of a functional determinant of differentiation-dependent expression in the involucrin gene

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Regulation of gene expression in developing epidermal epithelia

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Defining the regulatory factors required for epidermal gene expression

31 March 2020

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Identification and dissection of an enhancer controlling epithelial gene expression in skin

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Epidermal signal transduction and transcription factor activation in activated keratinocytes.

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Regulation of human involucrin promoter activity by a protein kinase C, Ras, MEKK1, MEK3, p38/RK, AP1 signal transduction pathway

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AP-1 in mouse development and tumorigenesis

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c-Jun is essential for normal mouse development and hepatogenesis

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Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

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Functions of c-Jun in liver and heart development

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JunB can substitute for Jun in mouse development and cell proliferation

31 March 2020

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Are desmosomes more than tethers for intermediate filaments?

31 March 2020

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Directed actin polymerization is the driving force for epithelial cell-cell adhesion

31 March 2020

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Desmosomal adhesion regulates epithelial morphogenesis and cell positioning

31 March 2020

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

31 March 2020

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APC mutations occur early during colorectal tumorigenesis

31 March 2020

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A common human skin tumour is caused by activating mutations in beta-catenin

31 March 2020

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Expression of E-cadherin in skin carcinomas

31 March 2020

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Cytomechanics of cadherin-mediated cell-cell adhesion

31 March 2020

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The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn

31 March 2020

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Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin

31 March 2020

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Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome

31 March 2020

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Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma

31 March 2020

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α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane

31 March 2020

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Skin and hair follicle integrity is crucially dependent on beta 1 integrin expression on keratinocytes

31 March 2020

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Conditional ablation of beta1 integrin in skin. Severe defects in epidermal proliferation, basement membrane formation, and hair follicle invagination

31 March 2020

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Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival

31 March 2020

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Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice.

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31 March 2020

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Structure and function of hemidesmosomes: more than simple adhesion complexes

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Molecular complexity of the cutaneous basement membrane zone. Revelations from the paradigms of epidermolysis bullosa

31 March 2020

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Keratinocyte growth factor is required for hair development but not for wound healing

31 March 2020

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Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

31 March 2020

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c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin

31 March 2020

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Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice

31 March 2020

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The biological consequences of excess GM-CSF levels in transgenic mice also lacking high-affinity receptors for GM-CSF

31 March 2020

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Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene

31 March 2020

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The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase.

31 March 2020

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Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

31 March 2020

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Strain-dependent epithelial defects in mice lacking the EGF receptor

31 March 2020

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Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype

31 March 2020

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Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter

31 March 2020

1 reference

Epidermal expression of transforming growth factor-alpha in transgenic mice: induction of spontaneous and 12-O-tetradecanoylphorbol-13-acetate-induced papillomas via a mechanism independent of Ha-ras activation or overexpression

31 March 2020

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The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

31 March 2020

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Interleukin 20: discovery, receptor identification, and role in epidermal function

31 March 2020

1 reference

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

31 March 2020

1 reference

Actin dynamics and cell-cell adhesion in epithelia

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG758

1 reference

PubMed ID

11972157

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

11972157