(Q30155139)

8 June 2017

title

Modification of a small β-barrel protein, to give pseudo-amyloid structures, inhibits amyloid β-peptide aggregation (English)

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8 June 2017

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Hisakazu Mihara

3

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author name string

Yuko Murakoshi

series ordinal

1

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8 June 2017

Tsuyoshi Takahashi

series ordinal

2

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8 June 2017

language of work or name

English

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publication date

1 February 2013

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Chemistry—A European Journal

8 June 2017

published in

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8 June 2017

volume

19

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8 June 2017

issue

14

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8 June 2017

page(s)

4525-4531

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Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders

8 June 2017

cites work

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Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

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Laser-induced liquid bead ion desorption mass spectrometry: an approach to precisely monitor the oligomerization of the β-amyloid peptide

21 January 2018

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Insight into the kinetic of amyloid beta (1-42) peptide self-aggregation: elucidation of inhibitors' mechanism of action

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Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

21 January 2018

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Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity

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Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity

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Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism.

21 January 2018

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The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

21 January 2018

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Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro

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A hybrid molecule that prohibits amyloid fibrils and alleviates neuronal toxicity induced by beta-amyloid (1-42)

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Inhibition of Alzheimer's amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo

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Synthesis and biological evaluation of clicked curcumin and clicked KLVFFA conjugates as inhibitors of beta-amyloid fibril formation.

21 January 2018

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A peptide hairpin inhibitor of amyloid beta-protein oligomerization and fibrillogenesis

21 January 2018

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Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

21 January 2018

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Novel amyloid-beta specific scFv and VH antibody fragments from human and mouse phage display antibody libraries

21 January 2018

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An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease

21 January 2018

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Rational design of amyloid beta peptide-binding proteins: pseudo-Abeta beta-sheet surface presented in green fluorescent protein binds tightly and preferentially to structured Abeta

21 January 2018

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Embedding the amyloid beta-peptide sequence in green fluorescent protein inhibits Abeta oligomerization.

21 January 2018

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Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 January 2018

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Structure of a functional IGF2R fragment determined from the anomalous scattering of sulfur

21 January 2018

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21 January 2018

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Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11

21 January 2018

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The solubility and stability of recombinant proteins are increased by their fusion to NusA.

21 January 2018

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Analysis of protein-protein interaction surfaces using a combination of efficient lysine acetylation and nanoLC-MALDI-MS/MS applied to the E9:Im9 bacteriotoxin--immunity protein complex.

21 January 2018

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Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?

21 January 2018

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Design of peptides that form amyloid-like fibrils capturing amyloid beta1-42 peptides

21 January 2018

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FRET detection of amyloid β-peptide oligomerization using a fluorescent protein probe presenting a pseudo-amyloid structure

21 January 2018

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Designed Short Peptides that Form Amyloid-Like Fibrils in Coassembly with Amyloid β-Peptide (Aβ) Decrease the Toxicity of Aβ to Neuronal PC12 Cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/CHEM.201202762

1 reference

8 June 2017

1 reference