(Q30249258)

13 June 2017

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title

Cardiovascular complications and risk of death in sickle-cell disease (English)

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13 June 2017

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1

Mark T Gladwin

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PubMed ID

27353687

13 June 2017

language of work or name

English

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publication date

1 June 2016

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13 June 2017

1 reference

13 June 2017

387

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13 June 2017

10037

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13 June 2017

2565-2574

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https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

13 June 2017

1 reference

7 January 2021

Pathogenesis and treatment of sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary complications of sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Chronic hyper-hemolysis in sickle cell anemia: association of vascular complications and mortality with less frequent vasoocclusive pain

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension as a risk factor for death in patients with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension and nitric oxide depletion in sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Transgenic sickle mice have vascular inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Haemolysis and abnormal haemorheology in sickle cell anaemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Global burden of sickle cell anaemia in children under five, 2010-2050: modelling based on demographics, excess mortality, and interventions

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Sickle cell disease in Africa: a neglected cause of early childhood mortality

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension in patients with sickle cell disease: a longitudinal study.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Erythrocyte density in sickle cell syndromes is associated with specific clinical manifestations and hemolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Association between hemolysis and albuminuria in adults with sickle cell anemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Cardiovascular abnormalities in sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Hemodynamic predictors of mortality in adults with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Elevated pulse pressure is associated with hemolysis, proteinuria and chronic kidney disease in sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Mortality in sickle cell disease. Life expectancy and risk factors for early death.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Chronic renal failure in sickle cell disease: risk factors, clinical course, and mortality

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Acute myocardial infarction in sickle cell disease: a systematic review

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Myocardial infarction in sickle-cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Myocardial infarction with normal coronary arteries in double heterozygous sickle-cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

NT-pro brain natriuretic peptide levels and the risk of death in the cooperative study of sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Mortality in adults with sickle cell disease and pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Left ventricular systolic function in sickle cell anemia: a meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

HEMODYNAMIC EFFECTS OF CHRONIC SEVERE ANEMIA

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Silent cerebral infarcts: a review on a prevalent and progressive cause of neurologic injury in sickle cell anemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Deconstructing endothelial dysfunction: soluble guanylyl cyclase oxidation and the NO resistance syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Impaired nitric oxide-mediated vasodilation in transgenic sickle mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Revisiting the hyperhemolysis paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Autologous transfusion of stored red blood cells increases pulmonary artery pressure.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Acute hemolytic vascular inflammatory processes are prevented by nitric oxide replacement or a single dose of hydroxyurea.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Genetic determinants of haemolysis in sickle cell anaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Extracellular hemin crisis triggers acute chest syndrome in sickle mice

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Erythroid DAMPs drive inflammation in SCD.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Mechanisms of hemolysis-associated platelet activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Hypercoagulability and thrombotic complications in hemolytic anemias.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary arterial hypertension: the clinical syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Definitions and diagnosis of pulmonary hypertension.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Updated Clinical Classification of Pulmonary Hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension in sickle cell disease: cardiac catheterization results and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

A hemodynamic study of pulmonary hypertension in sickle cell disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension diagnosed by right heart catheterisation in sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension associated with sickle cell disease: Clinical and laboratory endpoints and disease outcomes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

An elevated estimated pulmonary arterial systolic pressure, whenever measured, is associated with excess mortality in adults with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Estimated pulmonary artery systolic pressure and sickle cell disease: a meta-analysis and systematic review

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Prevalence of pulmonary hypertension in sickle cell anaemia patients of a tertiary hospital in Nigeria

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Prevalence and risk factors for pulmonary artery systolic hypertension among sickle cell disease patients in Nigeria

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Transthoracic echocardiography and 6-minute walk test in Kuwaiti sickle cell disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Venous thromboembolism incidence in the Cooperative Study of Sickle Cell Disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Successful pulmonary thromboendarterectomy in two patients with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Riociguat for the treatment of chronic thromboembolic pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Evaluation of 107 patients with sickle cell anemia through tissue Doppler and myocardial performance index

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Ventricular diastolic dysfunction in sickle cell anemia is common but not associated with myocardial iron deposition.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Left ventricular hypertrophy and diastolic dysfunction in children with sickle cell disease are related to asleep and waking oxygen desaturation.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Myocardial ischaemia in sickle cell anaemia: evaluation using a new scoring system.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Myocardial infarction and transient ventricular dysfunction in an adolescent with sickle cell disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Myocardial injury or infarction associated with fat embolism in sickle cell disease: a report of three cases with survival.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Evolution of novel small-molecule therapeutics targeting sickle cell vasculopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Proteomic identification of altered apolipoprotein patterns in pulmonary hypertension and vasculopathy of sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Myocardial ischaemia in children with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Myocardial infarction following sickle cell chest syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Transient left ventricular dysfunction in childhood sickle cell disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Causes of death in sickle cell disease: an autopsy study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Patterns of mortality in sickle cell disease in the United Kingdom

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension in sickle cell hemoglobinopathy: a clinicopathologic study of 20 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Pulmonary hypertension and cor pulmonale during severe acute chest syndrome in sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Continuous electrocardiographic monitoring in patients with sickle-cell anemia during pain crisis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Increased QT dispersion in sickle cell disease: effect of pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

Prolongation of QTc intervals and risk of death among patients with sickle cell disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2816%2900647-4

7 January 2021

10.1016/S0140-6736(16)00647-4

Identifiers

DOI

1 reference

13 June 2017

1 reference

PubMed ID

27353687