(Q30276619)

17 August 2017

Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer (English)

1 reference

17 August 2017

David MacPherson

16

0 references

author name string

Dong-Wook Kim

1

1 reference

17 August 2017

Nan Wu

2

1 reference

17 August 2017

Young-Chul Kim

3

1 reference

17 August 2017

Pei Feng Cheng

4

1 reference

17 August 2017

Ryan Basom

5

1 reference

17 August 2017

Dongkyoon Kim

6

1 reference

17 August 2017

Colin T Dunn

7

1 reference

17 August 2017

Anastasia Y Lee

8

1 reference

17 August 2017

Keebeom Kim

9

1 reference

17 August 2017

Chang Sup Lee

10

1 reference

17 August 2017

Andrew Singh

11

1 reference

17 August 2017

Adi F Gazdar

12

1 reference

17 August 2017

Chris R Harris

13

1 reference

17 August 2017

Robert N Eisenman

14

1 reference

17 August 2017

Kwon-Sik Park

15

1 reference

17 August 2017

1 June 2016

1 reference

17 August 2017

1 reference

17 August 2017

30

1 reference

17 August 2017

11

1 reference

17 August 2017

1289-1299

1 reference

describes a project that uses

17 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4911928/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Comprehensive genomic profiles of small cell lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Targeting the translation machinery in cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Genetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

L-Myc expression by dendritic cells is required for optimal T-cell priming

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

PTEN is a potent suppressor of small cell lung cancer.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

MYC on the path to cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Phase II study of everolimus (RAD001) in previously treated small cell lung cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Promotion of direct reprogramming by transformation-deficient Myc.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

MYC as a regulator of ribosome biogenesis and protein synthesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Expression and activity of L-Myc in normal mouse development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

L-myc cooperates with ras to transform primary rat embryo fibroblasts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

dMyc transforms cells into super-competitors

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

Drosophila myc regulates organ size by inducing cell competition

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4911928

L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27298335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27298335

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.279307.116

1 reference

17 August 2017

1 reference

17 August 2017

PubMed publication ID

27298335

1 reference